Ebook: The Rise of Fetal and Neonatal Physiology: Basic Science to Clinical Care

During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal “breathing” movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance.

Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.

This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.

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During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal “breathing” movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance.

Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.

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During the mid- to late-twentieth century, study of the physiology of the developing fetus and newborn infant evolved rapidly to become a major discipline in the biomedical sciences. Initially of interest from a standpoint of function of the placenta and oxygenation of the fetus, the field advanced to explore both normal functional mechanisms as well as pathophysiologic aspects of their regulation. Examples include studying the role and regulation of circulatory vascular anatomic shunts in oxygenation, cardiac function, certain aspects of asphyxia in the fetus and newborn infant, the role of fetal “breathing” movements, cyclic electroencephalographic activity, and analysis of electronic monitoring of fetal heart rate variability and its significance.

Included in this book are reminisces of several dozen individuals who played a vital role in these developments. Overall, this survey considers a number of aspects of the development of the science of fetal and neonatal physiology, and its role in the greatly improved care of pregnant women and their newborn infants.

Content:
Front Matter....Pages i-xxvii
Introduction....Pages 1-6
A Scientific Genealogy: Early Development of Fetal–Neonatal Research....Pages 7-41
Oxford and the Development of Physiology, with Notes on the Nuffield Institute for Medical Research....Pages 43-62
Geoffrey S. Dawes: A Life in Science....Pages 63-77
Fetal Asphyxia and the Primate Colony in Puerto Rico....Pages 79-95
Embryology and Early Developmental Physiology....Pages 97-111
Some Aspects of the Physiology of the Placenta....Pages 113-135
Governmental Support of Research in Fetal and Newborn Physiology....Pages 137-165
Fetal–Neonatal Growth and Metabolism....Pages 167-182
Epigenetics and the Fetal Origins of Adult Health and Disease....Pages 183-206
Some Aspects of the Developing Brain and Nervous System....Pages 207-234
Related Developments in Fetal and Neonatal Endocrinology....Pages 235-255
Further Developments in Fetal and Neonatal Physiology....Pages 257-279
Additional Clinical Aspects of Developmental Physiology....Pages 281-325
Bioethical Issues in Research on the Fetus and Newborn Infant....Pages 327-365
Textbooks, Monographs, and Other Volumes on Fetal and Newborn Physiology....Pages 367-377
Fetal “Breathing” in the 1970s, and Fetal Heart Rate Analysis in the 1980s and Early 1990s....Pages 379-390
Dawes’ Contributions to Symposia and a Summing Up....Pages 391-419
Dawes as a Mentor: Reminisces of Former Graduate Students, Postdoctoral Fellows, and Associates....Pages 421-432
Early Years of the Society for Gynecologic Investigation, the Fetal and Neonatal Physiological Society, and Several Other Groups....Pages 433-461
Epilogue....Pages 463-476
Bibliography of Geoffrey S. Dawes....Pages 477-497
Back Matter....Pages 499-511
....Pages 513-533