Ebook: Molecular Mechanisms Controlling Transmembrane Transport
- Tags: Cell Biology, Biochemistry general
- Series: Topics in Current Genetics 9
- Year: 2004
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.
Content:
Transcriptional regulation of intestinal nutrient transporters....Pages 1-22
Generation of transporter isoforms by alternative splicing....Pages 23-45
Transport-dependent gene regulation by sequestration of transcriptional regulators....Pages 47-66
Regulation and function of ammonium carriers in bacteria, fungi, and plants....Pages 95-120
Osmoregulation and osmosensing by uptake carriers for compatible solutes in bacteria....Pages 121-153
Role of transporter-like sensors in glucose and amino acid signalling in yeast....Pages 155-178
The bacterial phosphotransferase system: a perfect link of sugar transport and signal transduction....Pages 179-205
Ancillary proteins in membrane targeting of transporters....Pages 207-234
Membrane trafficking of yeast transporters: mechanisms and physiological control of downregulation....Pages 273-323
Aquaporin-2 trafficking....Pages 353-377