Ebook: Coronary Microvascular Dysfunction
- Tags: Cardiology, Angiology, Minimally Invasive Surgery
- Year: 2014
- Publisher: Springer-Verlag Mailand
- Edition: 1
- Language: English
- pdf
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
Content:
Front Matter....Pages i-xii
Front Matter....Pages 1-1
Physiology of Coronary Microcirculation....Pages 3-30
Mechanisms of Coronary Microvascular Dysfunction....Pages 31-47
Methods to Assess Coronary Microvascular Function....Pages 49-72
Front Matter....Pages 73-73
CMD in the Absence of Myocardial Diseases and Obstructive CAD....Pages 75-114
CMD in Myocardial Diseases....Pages 115-143
CMD in Obstructive CAD....Pages 145-180
Iatrogenic Coronary Microvascular Dysfunction....Pages 181-192
Front Matter....Pages 193-193
Treatment of Primary CMD....Pages 195-218
Treatment of CMD in Myocardial Diseases....Pages 219-224
Treatment of CMD in Obstructive CAD....Pages 225-240
Prevention of Iatrogenic CMD....Pages 241-251
Back Matter....Pages 253-257