Ebook: Neurobiology of Respiration

Respiration is an area of the medical study that undergoes fast developments. A better understanding of the neural and cellular mechanisms underlying respiratory disorders and lung function is essential for the evidence-based pharmacotherapy and for optimizing the patient care and prophylactic measures to improve the health and quality of life. This comprehensive book is a blend of basic and clinical research. The book is thought to promote the translation of science into clinical practice. The book presents an update on the areas of current research and clinical interest in the neurobiology of the respiratory system. Recent innovations in detection and management of respiratory diseases are described. The book will be a base of reference in the field of respiration for years to come and a source of future research ideas. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for ‘bench to bedside’ treatments of lung diseases.

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Respiration is a field of the scientific study that undergoes fast developments. A better understanding of the cellular and neural mechanisms underlying respiratory disorders and lung function is essential for the use of the evidence-based therapy and for optimizing the patient care and prophylactic measures. This book provides a comprehensive update on the basic and clinical respiratory research, and on the detection and management of respiratory pathologies. The molecular signaling lies at the base of the pathophysiology of the respiratory system and therapeutic interventions. The neurobiological studies have just started to unravel the complexities of how the molecular signals are translated into respiratory regulation in health and disease. This book helps translate non-clinical findings into clinical applications. It provides diagnostic tips that help the clinician in qualified decision making and describes novel biomarkers that facilitate diagnosis. The book also tackles the importance of the knowledge of the psychosomatic background of disease in getting the optimal patient outcome. The interventional epidemiological studies included in the book correspond to translational medicine that encompasses the basic and social sciences with the goal to improve the health and quality of life. The chapters presented in the book describe the findings of original studies, which were thoughtfully planned and executed in a controlled manner. The book satisfies a requirement for staying abreast of the latest developments in both scientific and clinical sides of respiratory neurobiology. The book will be an enduring base of reference in the field of respiration for years to come. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for ‘bench-to-bedside’ treatments of respiratory disorders.

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Respiration is a field of the scientific study that undergoes fast developments. A better understanding of the cellular and neural mechanisms underlying respiratory disorders and lung function is essential for the use of the evidence-based therapy and for optimizing the patient care and prophylactic measures. This book provides a comprehensive update on the basic and clinical respiratory research, and on the detection and management of respiratory pathologies. The molecular signaling lies at the base of the pathophysiology of the respiratory system and therapeutic interventions. The neurobiological studies have just started to unravel the complexities of how the molecular signals are translated into respiratory regulation in health and disease. This book helps translate non-clinical findings into clinical applications. It provides diagnostic tips that help the clinician in qualified decision making and describes novel biomarkers that facilitate diagnosis. The book also tackles the importance of the knowledge of the psychosomatic background of disease in getting the optimal patient outcome. The interventional epidemiological studies included in the book correspond to translational medicine that encompasses the basic and social sciences with the goal to improve the health and quality of life. The chapters presented in the book describe the findings of original studies, which were thoughtfully planned and executed in a controlled manner. The book satisfies a requirement for staying abreast of the latest developments in both scientific and clinical sides of respiratory neurobiology. The book will be an enduring base of reference in the field of respiration for years to come. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for ‘bench-to-bedside’ treatments of respiratory disorders.

Content:
Front Matter....Pages i-xii
Altered Histone Deacetylase Activity and iNOS Expression in Cells Isolated from Induced Sputum of COPD Patients Treated with Tiotropium....Pages 1-6
Involvement of NF-?B and Muscle Specific E3 Ubiquitin Ligase MuRF1 in Cigarette Smoke-Induced Catabolism in C2 Myotubes....Pages 7-17
Siglec-8 in Induced Sputum of COPD Patients....Pages 19-23
Essential Amino Acid Leucine and Proteasome Inhibitor MG132 Attenuate Cigarette Smoke Induced Catabolism in C2 Myotubes....Pages 25-33
Smoking Denial in Cardiovascular Disease Studies....Pages 35-38
Differential Effects of Kainic Acid Lesions in Medullary Raphe on Cough and Sneeze in Anesthetized Rabbits....Pages 39-45
Detection of Chlamydophila Pneumoniae Antigens in Patients with Chronic Cough....Pages 47-50
Antioxidant Activity of Herbal Polysaccharides and Cough Reflex....Pages 51-57
Cytoglobin and Neuroglobin in the Human Brainstem and Carotid Body....Pages 59-64
Flow Cytometry in the Diagnosis of Influenza....Pages 65-70
Accuracy of Rapid Influenza Detection Test in Diagnosis of Influenza A and B Viruses in Children Less Than 59 Months Old....Pages 71-76
Virological Monitoring of Influenza Activity and Influenza-Like Illness in the Epidemic Season 2011–2012 in Poland....Pages 77-82
Incidence of Chlamydophila Pneumoniae Infection in Children During 2007–2010....Pages 83-87
Clinical Features and Outcomes of Influenza A and B Infections in Children....Pages 89-96
Hyponatremia in Children Hospitalized due to Pneumonia....Pages 97-102
Prevalence of Acute Respiratory Tract Diseases Among Soldiers Deployed for Military Operations in Iraq and Afghanistan....Pages 103-108
Sinusitis in People Living in the Medieval Ages....Pages 109-116
Immunization Coverage Against Capsular Bacteria in Splenectomized Patients....Pages 117-124
Umbilical Cord Blood Gas Content, Postnatal State of Neonates, and Lactation After Caesarean and Natural Childbirth....Pages 125-132
Respiratory Function in Pregnant Women....Pages 133-138
Lung Function in Patients with Gastro-Esophageal Reflux Disease and Respiratory Symptoms....Pages 139-145
Efficacy of Noninvasive Mechanical Ventilation in Obese Patients with Chronic Respiratory Failure....Pages 147-151
Near-Infrared Hemoencephalography for Monitoring Blood Oxygenation in Prefrontal Cortical Areas in Diagnosis and Therapy of Developmental Dyslexia....Pages 153-160
Occlusal Stabilization Splint Therapy in Orofacial Pain and Tension-Type Headache....Pages 161-166
Dynamics of Upper Airways During the Muller Maneuver in Healthy Subjects: A Cine MRI Study....Pages 167-173
EMG Analysis of Human Inspiratory Muscle Resistance to Fatigue During Exercise....Pages 175-180
Assessment of Temporomandibular Joint Disease....Pages 181-188
Spirometry Day: A Means to Enhance Social Knowledge on Respiratory Diseases....Pages 189-195
Lung Function in Divers....Pages 197-205
Influence of Traffic-Related Air Pollutants on Lung Function....Pages 207-211
Fractional Exhaled Nitric Oxide in Clinical Trials: An Overview....Pages 213-219
Real-Time Breath Analysis in Type 2 Diabetes Patients During Cognitive Effort....Pages 221-227
Exhaled Nitric Oxide in Specific Inhalation Challenge....Pages 229-235
Integration of Simulated Multipotential Signals: The Role of Integration Window Width and of the Number of Spikes....Pages 237-245
Functional and Topographic Concordance of Right Atrial Neural Structures Inducing Sinus Tachycardia....Pages 247-253
Occurrence of Disseminated Intravascular Coagulation in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Induced Pneumonia in the Rat....Pages 255-264
Implementation of Non-invasive Methods in the Diagnosis of Diisocyanate-Induced Asthma....Pages 265-272
Evaluation of a 4-Steps-1-Day Whole Body Challenge Protocol for the Diagnosis of Occupational Asthma due to Diisocyanates....Pages 273-282
Occupational Allergic Respiratory Diseases in Garbage Workers: Relevance of Molds and Actinomycetes....Pages 283-292
Th1, Th2, Th17, and Regulatory Cytokines in Children with Different Clinical Forms of Allergy....Pages 293-300
Soluble Receptor for Urokinase Plasminogen Activator in Community-Acquired Pneumonia in Children....Pages 301-311
Hypersensitivity Pneumonitis due to Metalworking Fluids: How to Find the Antigens....Pages 313-320
Angiogenic Axis Angiopoietin-1 and Angiopoietin-2/Tie-2 in Non-Small Cell Lung Cancer: A Bronchoalveolar Lavage and Serum Study....Pages 321-328
Cancer Incidence in Pulmonary Vasculitis....Pages 329-334
Influence of Delays in Diagnosis and Treatment on Survival in Small Cell Lung Cancer Patients....Pages 335-340
Familial Idiopathic Pulmonary Fibrosis....Pages 341-348
High Resolution Computed Tomography in 2-Year Follow-Up of Stage I Sarcoidosis....Pages 349-353
Altruistic Aptitude: Age-Dependent Influence of Temperament and Emotional Intelligence....Pages 355-362
Effect of Socio-Economic Status on Quality of Life in People Affected with Respiratory Allergy....Pages 363-367
Exposure to Paracetamol and Antibiotics in Early Life and Elevated Risk of Asthma in Childhood....Pages 369-374
Health Behaviors and Quality of Life Among Patients with Chronic Respiratory Disease....Pages 375-383
Attitudes Toward Euthanasia Among Polish Physicians, Nurses and People Who Have No Professional Experience with the Terminally Ill....Pages 385-392
Death as a Result of Violent Asphyxia in Autopsy Reports....Pages 393-400
Respiratory and Systemic Infections in Children with Severe Aplastic Anemia on Immunosuppressive Therapy....Pages 401-406
Back Matter....Pages 407-412
....Pages 413-416