Ebook: Crossroads Between Innate and Adaptive Immunity IV

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions. ​

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This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions.

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This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions.

Content:
Front Matter....Pages i-xii
Vita-PAMPs: Signatures of Microbial Viability....Pages 1-8
Innate Lymphoid Cells in Immunity and Disease....Pages 9-26
Tuning Cross-Presentation of Apoptotic T Cells in Immunopathology....Pages 27-35
Regulation of Type 2 Immunity by Basophils....Pages 37-41
Crosstalk Between Adaptive and Innate Immune Cells Leads to High Quality Immune Protection at the Mucosal Borders....Pages 43-47
The Interaction Between Filarial Parasites and Human Monocyte/Macrophage Populations....Pages 49-56
Innate-Like B Cells and Their Rules of Engagement....Pages 57-66
The CD28/B7 Pathway: A Novel Regulator of Plasma Cell Function....Pages 67-75
Memory CD8+ T Cell Protection....Pages 77-86
Human T Follicular Helper Cells: Development and Subsets....Pages 87-94
Differentiation and Activation of ?? T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors....Pages 95-105
Decisions on the Road to Memory....Pages 107-120
Targeting the Skin for Microneedle Delivery of Influenza Vaccine....Pages 121-132
Back Matter....Pages 133-136

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This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions.

Content:
Front Matter....Pages i-xii
Vita-PAMPs: Signatures of Microbial Viability....Pages 1-8
Innate Lymphoid Cells in Immunity and Disease....Pages 9-26
Tuning Cross-Presentation of Apoptotic T Cells in Immunopathology....Pages 27-35
Regulation of Type 2 Immunity by Basophils....Pages 37-41
Crosstalk Between Adaptive and Innate Immune Cells Leads to High Quality Immune Protection at the Mucosal Borders....Pages 43-47
The Interaction Between Filarial Parasites and Human Monocyte/Macrophage Populations....Pages 49-56
Innate-Like B Cells and Their Rules of Engagement....Pages 57-66
The CD28/B7 Pathway: A Novel Regulator of Plasma Cell Function....Pages 67-75
Memory CD8+ T Cell Protection....Pages 77-86
Human T Follicular Helper Cells: Development and Subsets....Pages 87-94
Differentiation and Activation of ?? T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors....Pages 95-105
Decisions on the Road to Memory....Pages 107-120
Targeting the Skin for Microneedle Delivery of Influenza Vaccine....Pages 121-132
Back Matter....Pages 133-136
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