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Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.




Stem cells, whose impact will be revolutionary, provide enormous opportunities for both biological and future clinical applications. This book addresses state-of-the art concepts on stem cell nano-engineering, pluripotent stem cells, and cellular reprogramming as well as regenerative medicine.

Advances in Stem Cell Research is an important volume, as it is comprehensive and covers all new aspects of stem cell biology, from basic research to clinical applications. There are 18 chapters written by internationally renowned stem cell scientists. This up-to-date text will give the reader a complete understanding of the exciting stem cell science and its applications. It will serve as a valuable reference for researchers and students.

A valuable books for postgraduate students and advanced undergraduate students in cell biology, genetics, developmental biology, and biotechnology; stem cell researchers and clinicians; engineers in the field of regenerative medicine.


Stem cells, whose impact will be revolutionary, provide enormous opportunities for both biological and future clinical applications. This book addresses state-of-the art concepts on stem cell nano-engineering, pluripotent stem cells, and cellular reprogramming as well as regenerative medicine.

Advances in Stem Cell Research is an important volume, as it is comprehensive and covers all new aspects of stem cell biology, from basic research to clinical applications. There are 18 chapters written by internationally renowned stem cell scientists. This up-to-date text will give the reader a complete understanding of the exciting stem cell science and its applications. It will serve as a valuable reference for researchers and students.

A valuable books for postgraduate students and advanced undergraduate students in cell biology, genetics, developmental biology, and biotechnology; stem cell researchers and clinicians; engineers in the field of regenerative medicine.
Content:
Front Matter....Pages i-xiv
ES Cell Lines from Tetraploid Mouse Blastocysts....Pages 1-16
The Significance of Culture Adaptation of Embryonic Stem Cells for Regenerative Medicine....Pages 17-27
Biomanufacturing Human Pluripotent Stem Cells for Therapeutic Applications....Pages 29-48
hESC-Derived Hepatocytes....Pages 49-66
Advances in Induced Pluripotent Stem Cell Biology....Pages 67-84
iPS Cells: New Applications for Metabolic Liver Diseases....Pages 85-95
Vascular Differentiation of Human Pluripotent Stem Cells....Pages 97-115
Mechanism of MicroRNA-Mediated Global DNA Demethylation in Human iPS Cells....Pages 117-134
Microtechnological Approaches in Stem Cell Science....Pages 135-165
Application of Micro/Nanotechnology to Stem Cell Research and Technology....Pages 167-190
Spermatogonial Stem Cells....Pages 191-210
Cellular Reprogramming and Fate Conversion....Pages 211-225
Omics in Stem Cell Therapy: The Road Ahead....Pages 227-243
Microglia: The Bodyguard and the Hunter of the Adult Neurogenic Niche....Pages 245-279
Immunosuppressive Properties of Mesenchymal Stromal Cells....Pages 281-301
Cellular Therapy for Hematology Malignancies: Allogeneic Hematopoietic Stem Transplantation, Graft-Versus-Host Disease, and Graft Versus Leukemia Effects....Pages 303-366
Cardiac Versus Non-Cardiac Stem Cells to Repair the Heart: The Role of Autocrine/Paracrine Signals....Pages 367-382
Adult Neurogenesis in Alzheimer’s Disease and Therapies....Pages 383-393
Back Matter....Pages 395-398


Stem cells, whose impact will be revolutionary, provide enormous opportunities for both biological and future clinical applications. This book addresses state-of-the art concepts on stem cell nano-engineering, pluripotent stem cells, and cellular reprogramming as well as regenerative medicine.

Advances in Stem Cell Research is an important volume, as it is comprehensive and covers all new aspects of stem cell biology, from basic research to clinical applications. There are 18 chapters written by internationally renowned stem cell scientists. This up-to-date text will give the reader a complete understanding of the exciting stem cell science and its applications. It will serve as a valuable reference for researchers and students.

A valuable books for postgraduate students and advanced undergraduate students in cell biology, genetics, developmental biology, and biotechnology; stem cell researchers and clinicians; engineers in the field of regenerative medicine.
Content:
Front Matter....Pages i-xiv
ES Cell Lines from Tetraploid Mouse Blastocysts....Pages 1-16
The Significance of Culture Adaptation of Embryonic Stem Cells for Regenerative Medicine....Pages 17-27
Biomanufacturing Human Pluripotent Stem Cells for Therapeutic Applications....Pages 29-48
hESC-Derived Hepatocytes....Pages 49-66
Advances in Induced Pluripotent Stem Cell Biology....Pages 67-84
iPS Cells: New Applications for Metabolic Liver Diseases....Pages 85-95
Vascular Differentiation of Human Pluripotent Stem Cells....Pages 97-115
Mechanism of MicroRNA-Mediated Global DNA Demethylation in Human iPS Cells....Pages 117-134
Microtechnological Approaches in Stem Cell Science....Pages 135-165
Application of Micro/Nanotechnology to Stem Cell Research and Technology....Pages 167-190
Spermatogonial Stem Cells....Pages 191-210
Cellular Reprogramming and Fate Conversion....Pages 211-225
Omics in Stem Cell Therapy: The Road Ahead....Pages 227-243
Microglia: The Bodyguard and the Hunter of the Adult Neurogenic Niche....Pages 245-279
Immunosuppressive Properties of Mesenchymal Stromal Cells....Pages 281-301
Cellular Therapy for Hematology Malignancies: Allogeneic Hematopoietic Stem Transplantation, Graft-Versus-Host Disease, and Graft Versus Leukemia Effects....Pages 303-366
Cardiac Versus Non-Cardiac Stem Cells to Repair the Heart: The Role of Autocrine/Paracrine Signals....Pages 367-382
Adult Neurogenesis in Alzheimer’s Disease and Therapies....Pages 383-393
Back Matter....Pages 395-398
....
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