Ebook: Fertility Preservation: Emerging Technologies and Clinical Applications
- Tags: Endocrinology, Urology/Andrology, Developmental Biology, Cell Biology, Obstetrics/Perinatology
- Year: 2012
- Publisher: Springer-Verlag New York
- Edition: 1
- Language: English
- pdf
A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more women in their late 30s to early 40s are attempting to get pregnant for the first time than ever before. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation.
In this book, the editors provide strategies for fertility preservation in women and men who require gonadotoxic treatment. In addition, epidemiologic, ethical, medico-legal, psychologic, and social aspects of fertility preservation are discussed. Using a format that combines concise scientific background with practical methodological information and easy-to-grasp algorithms, the chapters all conform to a uniform structure, including a brief abstract, keyword glossary, step by step protocol of laboratory procedures, key issues in commentary and a list of references. The result is a unique, practical reference guide for reproductive endocrinologists, urologists, embryologists, reproductive scientists, and oncologists.
A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more women in their late 30s to early 40s are attempting to get pregnant for the first time than ever before. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation.
In this book, the editors provide strategies for fertility preservation in women and men who require gonadotoxic treatment. In addition, epidemiologic, ethical, medico-legal, psychologic, and social aspects of fertility preservation are discussed. Using a format that combines concise scientific background with practical methodological information and easy-to-grasp algorithms, the chapters all conform to a uniform structure, including a brief abstract, keyword glossary, step by step protocol of laboratory procedures, key issues in commentary and a list of references. The result is a unique, practical reference guide for reproductive endocrinologists, urologists, embryologists, reproductive scientists, and oncologists.
A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more women in their late 30s to early 40s are attempting to get pregnant for the first time than ever before. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation.
In this book, the editors provide strategies for fertility preservation in women and men who require gonadotoxic treatment. In addition, epidemiologic, ethical, medico-legal, psychologic, and social aspects of fertility preservation are discussed. Using a format that combines concise scientific background with practical methodological information and easy-to-grasp algorithms, the chapters all conform to a uniform structure, including a brief abstract, keyword glossary, step by step protocol of laboratory procedures, key issues in commentary and a list of references. The result is a unique, practical reference guide for reproductive endocrinologists, urologists, embryologists, reproductive scientists, and oncologists.
Content:
Front Matter....Pages i-xvii
Front Matter....Pages 1-1
The Epidemiology of Fertility Preservation....Pages 3-18
Ethical Discussions in Approaching Fertility Preservation....Pages 19-25
Front Matter....Pages 27-27
Ovarian Follicle Development and Fertility Preservation....Pages 29-43
Impact of Chemotherapy and Radiotherapy on the Ovary....Pages 45-56
Impact of Chemotherapy and Radiotherapy on the Uterus....Pages 57-70
Ovarian Transposition....Pages 71-75
Embryo Cryopreservation and Alternative Controlled Ovarian Hyperstimulation Strategies for Fertility Preservation....Pages 77-88
Oocyte Cryopreservation....Pages 89-105
Ovarian Tissue Cryopreservation and Autotransplantation....Pages 107-119
Oocyte In Vitro Maturation: Formidable Obstacles on the Road to Fertility Preservation....Pages 121-128
Whole Ovary Cryopreservation....Pages 129-134
Risk of Transplanting Cryopreserved Ovarian Tissue in Women with Malignancies....Pages 135-144
Gonadotropin-Releasing Hormone Agonists in Fertility Preservation....Pages 145-157
Fertility Preservation in Gynecologic Malignancies....Pages 159-198
Third-Party Reproduction and Adoption After Cancer: Practical and Emotional Considerations....Pages 199-208
Pregnancy and Cancer Treatment....Pages 209-224
Fertility Preservation Strategies in Healthy Women....Pages 225-232
Approach to Fertility Preservation in Adult and Prepubertal Females....Pages 233-241
Front Matter....Pages 243-243
Spermatogenesis and Testicular Function....Pages 245-260
Impact of Radiotherapy and Chemotherapy on the Testis....Pages 261-270
Front Matter....Pages 243-243
Impact of Paternal Exposure to Gonadotoxins on Embryo and Offspring and the Male Evaluation....Pages 271-288
Update on Sperm Banking....Pages 289-301
Preservation of Sperm Isolates or Testicular Biopsy Samples....Pages 303-313
Germ Cell Transplantation and Neospermatogenesis....Pages 315-330
Testicular Tissue Transplantation for Fertility Preservation....Pages 331-343
Stem Cells and Fertility Preservation in Males....Pages 345-352
Approach to Fertility Preservation in Adult and Pre-pubertal Males....Pages 353-364
Front Matter....Pages 365-365
Embryo Cryopreservation and Alternative Strategies for Controlled Ovarian Hyperstimulation....Pages 367-370
Oocyte Cryopreservation....Pages 371-374
Ovarian Tissue Cryopreservation....Pages 375-379
Sperm Preparation and Freezing for Banking....Pages 381-386
Preservation of Sperm Isolates and Testicular Biopsy Samples for Banking....Pages 387-388
Testis Tissue Xenografting....Pages 389-393
Back Matter....Pages 395-407
A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more women in their late 30s to early 40s are attempting to get pregnant for the first time than ever before. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation.
In this book, the editors provide strategies for fertility preservation in women and men who require gonadotoxic treatment. In addition, epidemiologic, ethical, medico-legal, psychologic, and social aspects of fertility preservation are discussed. Using a format that combines concise scientific background with practical methodological information and easy-to-grasp algorithms, the chapters all conform to a uniform structure, including a brief abstract, keyword glossary, step by step protocol of laboratory procedures, key issues in commentary and a list of references. The result is a unique, practical reference guide for reproductive endocrinologists, urologists, embryologists, reproductive scientists, and oncologists.
Content:
Front Matter....Pages i-xvii
Front Matter....Pages 1-1
The Epidemiology of Fertility Preservation....Pages 3-18
Ethical Discussions in Approaching Fertility Preservation....Pages 19-25
Front Matter....Pages 27-27
Ovarian Follicle Development and Fertility Preservation....Pages 29-43
Impact of Chemotherapy and Radiotherapy on the Ovary....Pages 45-56
Impact of Chemotherapy and Radiotherapy on the Uterus....Pages 57-70
Ovarian Transposition....Pages 71-75
Embryo Cryopreservation and Alternative Controlled Ovarian Hyperstimulation Strategies for Fertility Preservation....Pages 77-88
Oocyte Cryopreservation....Pages 89-105
Ovarian Tissue Cryopreservation and Autotransplantation....Pages 107-119
Oocyte In Vitro Maturation: Formidable Obstacles on the Road to Fertility Preservation....Pages 121-128
Whole Ovary Cryopreservation....Pages 129-134
Risk of Transplanting Cryopreserved Ovarian Tissue in Women with Malignancies....Pages 135-144
Gonadotropin-Releasing Hormone Agonists in Fertility Preservation....Pages 145-157
Fertility Preservation in Gynecologic Malignancies....Pages 159-198
Third-Party Reproduction and Adoption After Cancer: Practical and Emotional Considerations....Pages 199-208
Pregnancy and Cancer Treatment....Pages 209-224
Fertility Preservation Strategies in Healthy Women....Pages 225-232
Approach to Fertility Preservation in Adult and Prepubertal Females....Pages 233-241
Front Matter....Pages 243-243
Spermatogenesis and Testicular Function....Pages 245-260
Impact of Radiotherapy and Chemotherapy on the Testis....Pages 261-270
Front Matter....Pages 243-243
Impact of Paternal Exposure to Gonadotoxins on Embryo and Offspring and the Male Evaluation....Pages 271-288
Update on Sperm Banking....Pages 289-301
Preservation of Sperm Isolates or Testicular Biopsy Samples....Pages 303-313
Germ Cell Transplantation and Neospermatogenesis....Pages 315-330
Testicular Tissue Transplantation for Fertility Preservation....Pages 331-343
Stem Cells and Fertility Preservation in Males....Pages 345-352
Approach to Fertility Preservation in Adult and Pre-pubertal Males....Pages 353-364
Front Matter....Pages 365-365
Embryo Cryopreservation and Alternative Strategies for Controlled Ovarian Hyperstimulation....Pages 367-370
Oocyte Cryopreservation....Pages 371-374
Ovarian Tissue Cryopreservation....Pages 375-379
Sperm Preparation and Freezing for Banking....Pages 381-386
Preservation of Sperm Isolates and Testicular Biopsy Samples for Banking....Pages 387-388
Testis Tissue Xenografting....Pages 389-393
Back Matter....Pages 395-407
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