Ebook: Regulatory RNAs in Prokaryotes

This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.

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This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.

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This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.
Content:
Front Matter....Pages i-xiv
Small RNAs with a Role in the Oxidative Stress Response of Bacteria....Pages 1-14
Hfq-associated Regulatory Small RNAs....Pages 15-50
A Current Overview of Regulatory RNAs in Staphylococcus Aureus....Pages 51-75
Pseudomonas Aeruginosa Small Regulatory RNAs....Pages 77-94
Natural Antisense Transcripts in Bacteria....Pages 95-108
6S RNA: A Regulator of Transcription....Pages 109-129
Archaea Employ Small RNAs as Regulators....Pages 131-145
Structure, Function and RNA Binding Mechanisms of the Prokaryotic Sm-like Protein Hfq....Pages 147-162
CRISPR/Cas and CRISPR/Cmr Immune Systems of Archaea....Pages 163-181
Control of Bacterial Heat Shock and Virulence Genes by RNA Thermometers....Pages 183-193
RNA Sensors of Intracellular Metabolites....Pages 195-219
Bioinformatics of Bacterial sRNAs and Their Targets....Pages 221-239
Computational Tools for Predicting sRNA Targets....Pages 241-253
Back Matter....Pages 255-258

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This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.
Content:
Front Matter....Pages i-xiv
Small RNAs with a Role in the Oxidative Stress Response of Bacteria....Pages 1-14
Hfq-associated Regulatory Small RNAs....Pages 15-50
A Current Overview of Regulatory RNAs in Staphylococcus Aureus....Pages 51-75
Pseudomonas Aeruginosa Small Regulatory RNAs....Pages 77-94
Natural Antisense Transcripts in Bacteria....Pages 95-108
6S RNA: A Regulator of Transcription....Pages 109-129
Archaea Employ Small RNAs as Regulators....Pages 131-145
Structure, Function and RNA Binding Mechanisms of the Prokaryotic Sm-like Protein Hfq....Pages 147-162
CRISPR/Cas and CRISPR/Cmr Immune Systems of Archaea....Pages 163-181
Control of Bacterial Heat Shock and Virulence Genes by RNA Thermometers....Pages 183-193
RNA Sensors of Intracellular Metabolites....Pages 195-219
Bioinformatics of Bacterial sRNAs and Their Targets....Pages 221-239
Computational Tools for Predicting sRNA Targets....Pages 241-253
Back Matter....Pages 255-258
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