Ebook: Metagenomics of the Human Body

Metagenomics of the Human Body introduces readers to the major findings from the human genome project and at the same time presents the crossover to the human metagenome/microbiome, which we are only starting to understand through the advent of newly emerging technologies and other developments. The book brings a new perspective by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. As the field of metagenomics continues to evolve, Metagenomics of the Human Body brings together leaders in the field and their unique perspectives on this topic. The authors focus on the human genome and recent developments in the fields of microbial ecology and metagenomics of the microbial species that are associated with the human body. They also discuss the enormous implications for health and disease. Metagenomics of the Human Body is ideal for scientists, clinicians, community activists, undergraduate and graduate level students, as well as ethical and legal groups associated with or interested in the issues surrounding the human genome. About the Editor Dr. Karen E. Nelson is the Director of the Rockville Campus of the J. Craig Venter Institute (JCVI) where she has been for the past 14 years. She was formerly the Director of Human Microbiology and Metagenomics in the Department of Human Genomic Medicine at the JCVI. She has authored or co-authored over 100 publications, and is currently Editor-in-Chief of the Springer journal Microbial Ecology. She is also a standing member of the NRC Committee on Biodefense, a member of the American Society for Microbiology (ASM) Communications Committee and a Fellow of the ASM.

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Metagenomics of the Human Body introduces readers to the major findings from the human genome project and at the same time presents the crossover to the human metagenome/microbiome, which we are only starting to understand through the advent of newly emerging technologies and other developments. The book brings a new perspective by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. As the field of metagenomics continues to evolve, Metagenomics of the Human Body brings together leaders in the field and their unique perspectives on this topic. The authors focus on the human genome and recent developments in the fields of microbial ecology and metagenomics of the microbial species that are associated with the human body. They also discuss the enormous implications for health and disease. Metagenomics of the Human Body is ideal for scientists, clinicians, community activists, undergraduate and graduate level students, as well as ethical and legal groups associated with or interested in the issues surrounding the human genome. About the Editor Dr. Karen E. Nelson is the Director of the Rockville Campus of the J. Craig Venter Institute (JCVI) where she has been for the past 14 years. She was formerly the Director of Human Microbiology and Metagenomics in the Department of Human Genomic Medicine at the JCVI. She has authored or co-authored over 100 publications, and is currently Editor-in-Chief of the Springer journal Microbial Ecology. She is also a standing member of the NRC Committee on Biodefense, a member of the American Society for Microbiology (ASM) Communications Committee and a Fellow of the ASM.

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Metagenomics of the Human Body introduces readers to the major findings from the human genome project and at the same time presents the crossover to the human metagenome/microbiome, which we are only starting to understand through the advent of newly emerging technologies and other developments. The book brings a new perspective by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. As the field of metagenomics continues to evolve, Metagenomics of the Human Body brings together leaders in the field and their unique perspectives on this topic. The authors focus on the human genome and recent developments in the fields of microbial ecology and metagenomics of the microbial species that are associated with the human body. They also discuss the enormous implications for health and disease. Metagenomics of the Human Body is ideal for scientists, clinicians, community activists, undergraduate and graduate level students, as well as ethical and legal groups associated with or interested in the issues surrounding the human genome. About the Editor Dr. Karen E. Nelson is the Director of the Rockville Campus of the J. Craig Venter Institute (JCVI) where she has been for the past 14 years. She was formerly the Director of Human Microbiology and Metagenomics in the Department of Human Genomic Medicine at the JCVI. She has authored or co-authored over 100 publications, and is currently Editor-in-Chief of the Springer journal Microbial Ecology. She is also a standing member of the NRC Committee on Biodefense, a member of the American Society for Microbiology (ASM) Communications Committee and a Fellow of the ASM.
Content:
Front Matter....Pages i-xvii
The Human Genome, Microbiomes, and Disease....Pages 1-14
Host Genotype and the Effect on Microbial Communities....Pages 15-41
The Human Microbiome and Host–Pathogen Interactions....Pages 43-61
The Human Virome....Pages 63-77
Selection and Sequencing of Strains as References for Human Microbiome Studies....Pages 79-90
The Human Vaginal Microbiome....Pages 91-115
The Human Lung Microbiome....Pages 117-143
The Human Skin Microbiome in Health and Skin Diseases....Pages 145-163
The Human Oral Metagenome....Pages 165-173
The Human and His Microbiome Risk Factors for Infections....Pages 175-216
Infectogenomics: Aspect of Host Responses to Microbes in Digestive Tract....Pages 217-230
Autoimmune Disease and the Human Metagenome....Pages 231-275
Metagenomic Applications and the Potential for Understanding Chronic Liver Disease....Pages 277-295
Symbiotic Gut Microbiota and the Modulation of Human Metabolic Phenotypes....Pages 297-306
MetaHIT: The European Union Project on Metagenomics of the Human Intestinal Tract....Pages 307-316
Implications of Human Microbiome Research for the Developing World....Pages 317-336
Back Matter....Pages 337-351

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Metagenomics of the Human Body introduces readers to the major findings from the human genome project and at the same time presents the crossover to the human metagenome/microbiome, which we are only starting to understand through the advent of newly emerging technologies and other developments. The book brings a new perspective by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. As the field of metagenomics continues to evolve, Metagenomics of the Human Body brings together leaders in the field and their unique perspectives on this topic. The authors focus on the human genome and recent developments in the fields of microbial ecology and metagenomics of the microbial species that are associated with the human body. They also discuss the enormous implications for health and disease. Metagenomics of the Human Body is ideal for scientists, clinicians, community activists, undergraduate and graduate level students, as well as ethical and legal groups associated with or interested in the issues surrounding the human genome. About the Editor Dr. Karen E. Nelson is the Director of the Rockville Campus of the J. Craig Venter Institute (JCVI) where she has been for the past 14 years. She was formerly the Director of Human Microbiology and Metagenomics in the Department of Human Genomic Medicine at the JCVI. She has authored or co-authored over 100 publications, and is currently Editor-in-Chief of the Springer journal Microbial Ecology. She is also a standing member of the NRC Committee on Biodefense, a member of the American Society for Microbiology (ASM) Communications Committee and a Fellow of the ASM.
Content:
Front Matter....Pages i-xvii
The Human Genome, Microbiomes, and Disease....Pages 1-14
Host Genotype and the Effect on Microbial Communities....Pages 15-41
The Human Microbiome and Host–Pathogen Interactions....Pages 43-61
The Human Virome....Pages 63-77
Selection and Sequencing of Strains as References for Human Microbiome Studies....Pages 79-90
The Human Vaginal Microbiome....Pages 91-115
The Human Lung Microbiome....Pages 117-143
The Human Skin Microbiome in Health and Skin Diseases....Pages 145-163
The Human Oral Metagenome....Pages 165-173
The Human and His Microbiome Risk Factors for Infections....Pages 175-216
Infectogenomics: Aspect of Host Responses to Microbes in Digestive Tract....Pages 217-230
Autoimmune Disease and the Human Metagenome....Pages 231-275
Metagenomic Applications and the Potential for Understanding Chronic Liver Disease....Pages 277-295
Symbiotic Gut Microbiota and the Modulation of Human Metabolic Phenotypes....Pages 297-306
MetaHIT: The European Union Project on Metagenomics of the Human Intestinal Tract....Pages 307-316
Implications of Human Microbiome Research for the Developing World....Pages 317-336
Back Matter....Pages 337-351
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