Ebook: Cell Fusion in Health and Disease
- Tags: Biomedicine general, Cell Biology, Membrane Biology
- Series: Advances in Experimental Medicine and Biology 713
- Year: 2011
- Publisher: Springer Netherlands
- Edition: 1
- Language: English
- pdf
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Volume 1 international leading experts will present up-to-date overviews about the current knowledge about cell fusion-mediating molecules in C. elegans and mammalian cells. Further topics of the book will focus on cell fusion in physiological processes including fertilization, placentation, skeletal muscle development, and tissue repair and will sum up the use of artificial cell fusion for cellular reprogramming and cancer vaccine development. Thus, Cell Fusion in Health and Disease Volume 1 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion in physiological processes and beyond.
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Volume 1 international leading experts will present up-to-date overviews about the current knowledge about cell fusion-mediating molecules in C. elegans and mammalian cells. Further topics of the book will focus on cell fusion in physiological processes including fertilization, placentation, skeletal muscle development, and tissue repair and will sum up the use of artificial cell fusion for cellular reprogramming and cancer vaccine development. Thus, Cell Fusion in Health and Disease Volume 1 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion in physiological processes and beyond.
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Volume 1 international leading experts will present up-to-date overviews about the current knowledge about cell fusion-mediating molecules in C. elegans and mammalian cells. Further topics of the book will focus on cell fusion in physiological processes including fertilization, placentation, skeletal muscle development, and tissue repair and will sum up the use of artificial cell fusion for cellular reprogramming and cancer vaccine development. Thus, Cell Fusion in Health and Disease Volume 1 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion in physiological processes and beyond.
Content:
Front Matter....Pages I-XII
Introduction....Pages 1-3
Heterochronic Control of AFF-1-Mediated Cell-to-Cell Fusion in C. elegans ....Pages 5-11
Role of SNAREs in Membrane Fusion....Pages 13-32
Molecular and Cellular Mechanisms of Mammalian Cell Fusion....Pages 33-64
Membrane Fusions During Mammalian Fertilization....Pages 65-80
Trophoblast Fusion....Pages 81-95
Macrophage Fusion and Multinucleated Giant Cells of Inflammation....Pages 97-111
Molecular Mechanisms of Myoblast Fusion Across Species....Pages 113-135
Cell-Fusion-Mediated Reprogramming: Pluripotency or Transdifferentiation? Implications for Regenerative Medicine....Pages 137-159
Cell Fusion and Tissue Regeneration....Pages 161-175
Dendritic Cell-Tumor Cell Fusion Vaccines....Pages 177-186
Back Matter....Pages 187-189
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Volume 1 international leading experts will present up-to-date overviews about the current knowledge about cell fusion-mediating molecules in C. elegans and mammalian cells. Further topics of the book will focus on cell fusion in physiological processes including fertilization, placentation, skeletal muscle development, and tissue repair and will sum up the use of artificial cell fusion for cellular reprogramming and cancer vaccine development. Thus, Cell Fusion in Health and Disease Volume 1 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion in physiological processes and beyond.
Content:
Front Matter....Pages I-XII
Introduction....Pages 1-3
Heterochronic Control of AFF-1-Mediated Cell-to-Cell Fusion in C. elegans ....Pages 5-11
Role of SNAREs in Membrane Fusion....Pages 13-32
Molecular and Cellular Mechanisms of Mammalian Cell Fusion....Pages 33-64
Membrane Fusions During Mammalian Fertilization....Pages 65-80
Trophoblast Fusion....Pages 81-95
Macrophage Fusion and Multinucleated Giant Cells of Inflammation....Pages 97-111
Molecular Mechanisms of Myoblast Fusion Across Species....Pages 113-135
Cell-Fusion-Mediated Reprogramming: Pluripotency or Transdifferentiation? Implications for Regenerative Medicine....Pages 137-159
Cell Fusion and Tissue Regeneration....Pages 161-175
Dendritic Cell-Tumor Cell Fusion Vaccines....Pages 177-186
Back Matter....Pages 187-189
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