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This valuable new title addresses the role of heat shock proteins and cellular stress responses in the brain, with a major focus on nerve cells and glia, namely oligodendrocytes and astrocytes. Heat shock proteins are involved in many physiological processes, including development and differentiation, organisation of the cytoarchitecture by binding to cytoskeletal elements, and regulation of the balance between cell death and survival.


This valuable new title addresses the role of heat shock proteins and cellular stress responses in the brain, with a major focus on nerve cells and glia, namely oligodendrocytes and astrocytes. Heat shock proteins are involved in many physiological processes, including development and differentiation, organisation of the cytoarchitecture by binding to cytoskeletal elements, and regulation of the balance between cell death and survival.
Content:
Front Matter....Pages i-xi
Heat Shock Proteins....Pages 1-12
Small Heat Shock Proteins and the Cytoskeleton....Pages 13-24
The Role of Hsps in Neuronal Differentiation and Development....Pages 25-37
Heme Oxygenase as a Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress Response....Pages 39-52
Heat Shock Proteins and the Regulation of Apoptosis....Pages 53-66
Assembly of Protein Aggregates in Neurodegeneration....Pages 67-79
The Role of Heat Shock Proteins during Neurodegeneration in Alzheimer’s, Parkinson’s and Huntington’s Disease....Pages 81-99
Heat Shock Proteins in Multiple Sclerosis....Pages 101-111
Back Matter....Pages 113-115


This valuable new title addresses the role of heat shock proteins and cellular stress responses in the brain, with a major focus on nerve cells and glia, namely oligodendrocytes and astrocytes. Heat shock proteins are involved in many physiological processes, including development and differentiation, organisation of the cytoarchitecture by binding to cytoskeletal elements, and regulation of the balance between cell death and survival.
Content:
Front Matter....Pages i-xi
Heat Shock Proteins....Pages 1-12
Small Heat Shock Proteins and the Cytoskeleton....Pages 13-24
The Role of Hsps in Neuronal Differentiation and Development....Pages 25-37
Heme Oxygenase as a Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress Response....Pages 39-52
Heat Shock Proteins and the Regulation of Apoptosis....Pages 53-66
Assembly of Protein Aggregates in Neurodegeneration....Pages 67-79
The Role of Heat Shock Proteins during Neurodegeneration in Alzheimer’s, Parkinson’s and Huntington’s Disease....Pages 81-99
Heat Shock Proteins in Multiple Sclerosis....Pages 101-111
Back Matter....Pages 113-115
....
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