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The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.




The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.




The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.


Content:
Front Matter....Pages i-xi
Editing Reactions from the Perspective of RNA Structure....Pages 1-32
Editing of tRNA for Structure and Function....Pages 33-50
RNA Editing by Adenosine Deaminases that Act on RNA (ADARs)....Pages 51-84
Insertion/Deletion Editing in Physarum polycephalum ....Pages 85-104
RNA Editing in Plant Mitochondria....Pages 105-122
RNA Editing in Chloroplasts....Pages 123-142
Working Together: the RNA Editing Machinery in Trypanosoma brucei ....Pages 143-164
RNA Editing Accessory Factors — the Example of mHel61p....Pages 165-179
The Function of RNA Editing in Trypanosomes....Pages 181-197
Evolutionary Aspects of RNA Editing....Pages 199-227
Back Matter....Pages 229-231


The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.


Content:
Front Matter....Pages i-xi
Editing Reactions from the Perspective of RNA Structure....Pages 1-32
Editing of tRNA for Structure and Function....Pages 33-50
RNA Editing by Adenosine Deaminases that Act on RNA (ADARs)....Pages 51-84
Insertion/Deletion Editing in Physarum polycephalum ....Pages 85-104
RNA Editing in Plant Mitochondria....Pages 105-122
RNA Editing in Chloroplasts....Pages 123-142
Working Together: the RNA Editing Machinery in Trypanosoma brucei ....Pages 143-164
RNA Editing Accessory Factors — the Example of mHel61p....Pages 165-179
The Function of RNA Editing in Trypanosomes....Pages 181-197
Evolutionary Aspects of RNA Editing....Pages 199-227
Back Matter....Pages 229-231
....
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