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This volume serves as a succinct and well-organized reference volume focused on inflammatory CNS disease to a wide audience. The text is comprised of four sections revolving around current areas of interest in the fields of neuroimmunology, virology, pharmacology and disease. Sections of this text focus on a specific category of diseases as well as the pharmacological, virological, and immunological effects of and on the disease.

Although many have covered this topic, few have provided a volume as concise and efficient. Each disease is broken down on a variety of scientific levels without getting into the history of the disease. This approach provides a succinct overview of a specific subject encompassing interrelated topics pertaining to neurology, immunology and disease. The information provided in Central Nervous System Diseases and Inflammation will be useful for researchers, clinicians, as well as a valuable resource for students interested in the fascinating arena of neuroinflammation.




This volume serves as a succinct and well-organized reference volume focused on inflammatory CNS disease to a wide audience. The text is comprised of four sections revolving around current areas of interest in the fields of neuroimmunology, virology, pharmacology and disease. Sections of this text focus on a specific category of diseases as well as the pharmacological, virological, and immunological effects of and on the disease.

Although many have covered this topic, few have provided a volume as concise and efficient. Each disease is broken down on a variety of scientific levels without getting into the history of the disease. This approach provides a succinct overview of a specific subject encompassing interrelated topics pertaining to neurology, immunology and disease. The information provided in Central Nervous System Diseases and Inflammation will be useful for researchers, clinicians, as well as a valuable resource for students interested in the fascinating arena of neuroinflammation.




This volume serves as a succinct and well-organized reference volume focused on inflammatory CNS disease to a wide audience. The text is comprised of four sections revolving around current areas of interest in the fields of neuroimmunology, virology, pharmacology and disease. Sections of this text focus on a specific category of diseases as well as the pharmacological, virological, and immunological effects of and on the disease.

Although many have covered this topic, few have provided a volume as concise and efficient. Each disease is broken down on a variety of scientific levels without getting into the history of the disease. This approach provides a succinct overview of a specific subject encompassing interrelated topics pertaining to neurology, immunology and disease. The information provided in Central Nervous System Diseases and Inflammation will be useful for researchers, clinicians, as well as a valuable resource for students interested in the fascinating arena of neuroinflammation.


Content:
Front Matter....Pages i-viii
Microglia: A CNS-Specific Tissue Macrophage....Pages 1-12
Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments....Pages 13-32
Pericytes....Pages 33-43
Imaging Microglia in the Central Nervous System: Past, Present and Future....Pages 45-57
Cytokines in CNS Inflammation and Disease....Pages 59-106
Arachidonic Acid Metabolites: Function in Neurotoxicity and Inflammation in the Central Nervous System....Pages 107-129
Pattern Recognition Receptors in CNS Disease....Pages 131-152
Central Nervous System Diseases and Inflammation....Pages 153-174
Chemokines and Autoimmune Demyelination....Pages 175-201
Chemokine Actions in the CNS: Insights from Transgenic Mice....Pages 203-219
Chemokines and Spinal Cord Injury....Pages 221-233
The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System....Pages 235-261
CNS Dendritic Cells in Inflammation and Disease....Pages 263-275
MHC Class I Expression and CD8 T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain....Pages 277-306
Back Matter....Pages 307-313


This volume serves as a succinct and well-organized reference volume focused on inflammatory CNS disease to a wide audience. The text is comprised of four sections revolving around current areas of interest in the fields of neuroimmunology, virology, pharmacology and disease. Sections of this text focus on a specific category of diseases as well as the pharmacological, virological, and immunological effects of and on the disease.

Although many have covered this topic, few have provided a volume as concise and efficient. Each disease is broken down on a variety of scientific levels without getting into the history of the disease. This approach provides a succinct overview of a specific subject encompassing interrelated topics pertaining to neurology, immunology and disease. The information provided in Central Nervous System Diseases and Inflammation will be useful for researchers, clinicians, as well as a valuable resource for students interested in the fascinating arena of neuroinflammation.


Content:
Front Matter....Pages i-viii
Microglia: A CNS-Specific Tissue Macrophage....Pages 1-12
Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments....Pages 13-32
Pericytes....Pages 33-43
Imaging Microglia in the Central Nervous System: Past, Present and Future....Pages 45-57
Cytokines in CNS Inflammation and Disease....Pages 59-106
Arachidonic Acid Metabolites: Function in Neurotoxicity and Inflammation in the Central Nervous System....Pages 107-129
Pattern Recognition Receptors in CNS Disease....Pages 131-152
Central Nervous System Diseases and Inflammation....Pages 153-174
Chemokines and Autoimmune Demyelination....Pages 175-201
Chemokine Actions in the CNS: Insights from Transgenic Mice....Pages 203-219
Chemokines and Spinal Cord Injury....Pages 221-233
The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System....Pages 235-261
CNS Dendritic Cells in Inflammation and Disease....Pages 263-275
MHC Class I Expression and CD8 T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain....Pages 277-306
Back Matter....Pages 307-313
....
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