Ebook: The Resolution of Inflammation
- Tags: Immunology, Cell Biology, Biochemistry general, Biomedicine general, Pharmacology/Toxicology
- Series: Progress in Inflammation Research
- Year: 2008
- Publisher: Birkhäuser Basel
- Edition: 1
- Language: English
- pdf
Much progress has been made in elucidating the mechanisms regulating the induction and progression of inflammatory diseases. More recently, however, it has become apparent that the manipulation of mechanisms governing the resolution of inflammation is an important way to develop novel strategies for the therapy of such diseases. This book provides an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area (e.g. pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments). The chapters are written by leading scientists in the field.
This topical volume is of interest to medical and scientific researchers in academia and industry working on inflammatory and cardiovascular diseases such as arthritis, asthma, bronchitis, atherosclerosis, and more.
Much progress has been made in elucidating the mechanisms regulating the induction and progression of inflammatory diseases. More recently, however, it has become apparent that the manipulation of mechanisms governing the resolution of inflammation is an important way to develop novel strategies for the therapy of such diseases. This book provides an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area (e.g. pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments). The chapters are written by leading scientists in the field.
This topical volume is of interest to medical and scientific researchers in academia and industry working on inflammatory and cardiovascular diseases such as arthritis, asthma, bronchitis, atherosclerosis, and more.
Much progress has been made in elucidating the mechanisms regulating the induction and progression of inflammatory diseases. More recently, however, it has become apparent that the manipulation of mechanisms governing the resolution of inflammation is an important way to develop novel strategies for the therapy of such diseases. This book provides an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area (e.g. pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments). The chapters are written by leading scientists in the field.
This topical volume is of interest to medical and scientific researchers in academia and industry working on inflammatory and cardiovascular diseases such as arthritis, asthma, bronchitis, atherosclerosis, and more.
Content:
Front Matter....Pages i-xii
The resolution of acute inflammation: A ‘tipping point’ in the development of chronic inflammatory diseases....Pages 1-18
Granulocyte apoptosis....Pages 19-37
Innate immune mechanisms in the resolution of inflammation....Pages 39-56
Cell surface molecular changes associated with apoptosis....Pages 57-73
Fate of macrophages once having ingested apoptotic cells: Lymphatic clearance or in situ apoptosis?....Pages 75-91
Novel lipid mediators in resolution and their aspirin triggered epimers: Lipoxins, resolvins, and protectins....Pages 93-117
Beyond inflammation: Lipoxins; resolution of inflammation and regulation of fibrosis....Pages 119-139
Anti-inflammatory glucocorticoids and annexin 1....Pages 141-158
The resolution of airway inflammation in asthma and chronic obstructive pulmonary disease....Pages 159-191
Resolution of glomerular inflammation....Pages 193-222
Resolution of mucosal inflammation....Pages 223-234
Back Matter....Pages 235-240
Much progress has been made in elucidating the mechanisms regulating the induction and progression of inflammatory diseases. More recently, however, it has become apparent that the manipulation of mechanisms governing the resolution of inflammation is an important way to develop novel strategies for the therapy of such diseases. This book provides an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area (e.g. pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments). The chapters are written by leading scientists in the field.
This topical volume is of interest to medical and scientific researchers in academia and industry working on inflammatory and cardiovascular diseases such as arthritis, asthma, bronchitis, atherosclerosis, and more.
Content:
Front Matter....Pages i-xii
The resolution of acute inflammation: A ‘tipping point’ in the development of chronic inflammatory diseases....Pages 1-18
Granulocyte apoptosis....Pages 19-37
Innate immune mechanisms in the resolution of inflammation....Pages 39-56
Cell surface molecular changes associated with apoptosis....Pages 57-73
Fate of macrophages once having ingested apoptotic cells: Lymphatic clearance or in situ apoptosis?....Pages 75-91
Novel lipid mediators in resolution and their aspirin triggered epimers: Lipoxins, resolvins, and protectins....Pages 93-117
Beyond inflammation: Lipoxins; resolution of inflammation and regulation of fibrosis....Pages 119-139
Anti-inflammatory glucocorticoids and annexin 1....Pages 141-158
The resolution of airway inflammation in asthma and chronic obstructive pulmonary disease....Pages 159-191
Resolution of glomerular inflammation....Pages 193-222
Resolution of mucosal inflammation....Pages 223-234
Back Matter....Pages 235-240
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