Ebook: Biological Calcification: Normal and Pathological Processes in the Early Stages
- Tags: Animal Physiology, Animal Anatomy / Morphology / Histology, Evolutionary Biology, Animal Biochemistry, Human Physiology, Orthopedics
- Year: 2007
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
This book follows a precursor volume devoted to biological calci?cation, - sued by the CRC Press, Boca Raton (Florida) in 1992. Several basic aspects of the calci?cation process were analyzed in it by outstanding authors who had unquestioned competence in their respective research areas. Its main aim was that of giving readers access to a series of papers which, even though they discussed divergent aspects of biological calci?cations drawn from the study of systems as different as vertebrate skeletons and mollusks, in vitro cultures and unicellular organisms, ectopic calci?cation and urinary stones, provided elements permitting a coherent approach to a comprehensive view of the calci?cation process in biological tissues. Now, almost 15 years after the publication of that book, a great variety of new data from a wide spectrum of biological organisms and systems has enriched our knowledge of the normal and pathological mechanisms which can lead to calci?cation. Even so, this whole process is still problematic: the new knowledge, concepts and ideas have often suggested that a de?nitive solution was close at hand, but the local mechanism through which the inorganic substance is laid down in organic matrices continues to be an elusive, largely enigmatic topic.
The topics falling under the heading biological calcification are exceedingly numerous and varied. They include systems as different as vertebrate skeletons and molluscs, in vitro cultures and unicellular organisms, ectopic calcification and urinary stones. Furthermore, the results are scattered through a huge number of scientific publications.
Although calcification is probably one of the most widespread biological processes, the mechanisms which lead to calcification of biological systems are still unexplained
For the first time, this book offers a critical review of the calcification process, of the organic and inorganic phases of mineralized tissues, focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. By collecting results from as many different sources as possible, and on the basis of personal experience, an integrative approach to a unified theory of this biological mechanism is given.
The topics falling under the heading biological calcification are exceedingly numerous and varied. They include systems as different as vertebrate skeletons and molluscs, in vitro cultures and unicellular organisms, ectopic calcification and urinary stones. Furthermore, the results are scattered through a huge number of scientific publications.
Although calcification is probably one of the most widespread biological processes, the mechanisms which lead to calcification of biological systems are still unexplained
For the first time, this book offers a critical review of the calcification process, of the organic and inorganic phases of mineralized tissues, focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. By collecting results from as many different sources as possible, and on the basis of personal experience, an integrative approach to a unified theory of this biological mechanism is given.
Content:
Front Matter....Pages I-XXI
Introduction....Pages 1-4
Historical Notes....Pages 5-21
Methodology....Pages 23-66
The Nature and Composition of the Inorganic Phase....Pages 67-103
The Shape of Inorganic Particles....Pages 105-144
The Size of Inorganic Particles....Pages 145-165
Calcifying Matrices: Bone and Tendons....Pages 167-230
Calcifying Matrices: Dentin and Cementum....Pages 231-259
Calcifying Matrices: Cartilage....Pages 261-301
Calcifying Matrices: Enamel....Pages 303-333
Calcifying Matrices: Lower Vertebrates....Pages 335-343
Calcifying Matrices: Invertebrates....Pages 345-366
Calcifying Matrices: Non-skeletal Structures....Pages 367-383
Calcifying Matrices: Pathological Calcifications....Pages 385-415
Calcifying Matrices: Acquired or Experimental Diseases; Heritable Disorders; Genetically Modified Animals....Pages 417-441
The Organic-inorganic Relationships in Calcifying Matrices....Pages 443-489
Main Suggested Calcification Mechanisms: Cells....Pages 491-506
Main Suggested Calcification Mechanisms: Extracellular Matrix....Pages 507-558
Conclusions....Pages 559-568
Back Matter....Pages 569-592
The topics falling under the heading biological calcification are exceedingly numerous and varied. They include systems as different as vertebrate skeletons and molluscs, in vitro cultures and unicellular organisms, ectopic calcification and urinary stones. Furthermore, the results are scattered through a huge number of scientific publications.
Although calcification is probably one of the most widespread biological processes, the mechanisms which lead to calcification of biological systems are still unexplained
For the first time, this book offers a critical review of the calcification process, of the organic and inorganic phases of mineralized tissues, focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. By collecting results from as many different sources as possible, and on the basis of personal experience, an integrative approach to a unified theory of this biological mechanism is given.
Content:
Front Matter....Pages I-XXI
Introduction....Pages 1-4
Historical Notes....Pages 5-21
Methodology....Pages 23-66
The Nature and Composition of the Inorganic Phase....Pages 67-103
The Shape of Inorganic Particles....Pages 105-144
The Size of Inorganic Particles....Pages 145-165
Calcifying Matrices: Bone and Tendons....Pages 167-230
Calcifying Matrices: Dentin and Cementum....Pages 231-259
Calcifying Matrices: Cartilage....Pages 261-301
Calcifying Matrices: Enamel....Pages 303-333
Calcifying Matrices: Lower Vertebrates....Pages 335-343
Calcifying Matrices: Invertebrates....Pages 345-366
Calcifying Matrices: Non-skeletal Structures....Pages 367-383
Calcifying Matrices: Pathological Calcifications....Pages 385-415
Calcifying Matrices: Acquired or Experimental Diseases; Heritable Disorders; Genetically Modified Animals....Pages 417-441
The Organic-inorganic Relationships in Calcifying Matrices....Pages 443-489
Main Suggested Calcification Mechanisms: Cells....Pages 491-506
Main Suggested Calcification Mechanisms: Extracellular Matrix....Pages 507-558
Conclusions....Pages 559-568
Back Matter....Pages 569-592
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