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The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. "Hox Gene Expression" starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes- their evolution, structure, normal and abnormal function. Researchers and graduate students in Biology and Medicine will benefit from this integrated overview of Hox gene activities.




The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.




The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.


Content:
Front Matter....Pages i-xiv
The Homeobox as a Key for Understanding the Principles of the Genetic Control of Development....Pages 1-13
Expression of Hox Genes in the Nervous System of Vertebrates....Pages 14-41
The Hox Gene Network in Vertebrate Limb Development....Pages 42-52
Evolution of Hox Gene Clusters....Pages 53-67
Evolutionary Genomics of Hox Gene Clusters....Pages 68-90
Chromatin and the Control of Hox Gene Expression....Pages 91-101
Homeobox-Containing Genes in Limb Regeneration....Pages 102-110
Hox Genes and Stem Cells....Pages 111-120
Deregulation of the Hox Gene Network and Cancer....Pages 121-133
Back Matter....Pages 134-149


The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.


Content:
Front Matter....Pages i-xiv
The Homeobox as a Key for Understanding the Principles of the Genetic Control of Development....Pages 1-13
Expression of Hox Genes in the Nervous System of Vertebrates....Pages 14-41
The Hox Gene Network in Vertebrate Limb Development....Pages 42-52
Evolution of Hox Gene Clusters....Pages 53-67
Evolutionary Genomics of Hox Gene Clusters....Pages 68-90
Chromatin and the Control of Hox Gene Expression....Pages 91-101
Homeobox-Containing Genes in Limb Regeneration....Pages 102-110
Hox Genes and Stem Cells....Pages 111-120
Deregulation of the Hox Gene Network and Cancer....Pages 121-133
Back Matter....Pages 134-149
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