Ebook: The Papillomaviruses
- Tags: Immunology, Infectious Diseases, Virology, Microbiology, Cancer Research
- Year: 2007
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
The papillomaviruses have emerged as the best understood viruses that cause cancer in humans. This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes. Most importantly, human papillomavirus infection has been shown to be a crucial event in the development of several human cancers, most notably cervical cancer, a leading cause of cancer death in women. The Papillomaviruses is an ideal book for scientists, professionals, clinicians, and graduate students in the fields of immunology, infectious disease, virology, microbiology, cell biology, and cancer biology and research.
The papillomaviruses have emerged as the best understood viruses that cause cancer in humans. This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes. Most importantly, human papillomavirus infection has been shown to be a crucial event in the development of several human cancers, most notably cervical cancer, a leading cause of cancer death in women. The Papillomaviruses is an ideal book for scientists, professionals, clinicians, and graduate students in the fields of immunology, infectious disease, virology, microbiology, cell biology, and cancer biology and research.
The papillomaviruses have emerged as the best understood viruses that cause cancer in humans. This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes. Most importantly, human papillomavirus infection has been shown to be a crucial event in the development of several human cancers, most notably cervical cancer, a leading cause of cancer death in women. The Papillomaviruses is an ideal book for scientists, professionals, clinicians, and graduate students in the fields of immunology, infectious disease, virology, microbiology, cell biology, and cancer biology and research.
Content:
Front Matter....Pages i-xix
Principles of Human Tumor Virology....Pages 1-11
History of Papillomavirus Research....Pages 13-28
Phylogeny and Typing of Papillomaviruses....Pages 29-44
The Differentiation-Dependent Life Cycle of Human Papillomaviruses in Keratinocytes....Pages 45-67
Papillomavirus Structure and Assembly....Pages 69-88
Viral Entry and Receptors....Pages 89-107
Human Papillomavirus Transcription....Pages 109-144
DNA Replication of Papillomaviruses....Pages 145-174
Papillomavirus E5 Proteins....Pages 175-196
Human Papillomavirus E6 and E7 Oncogenes....Pages 197-252
In Vivo Models for the Study of Animal and Human Papillomaviruses....Pages 253-275
The Humoral Immune Response to Human Papillomavirus....Pages 277-312
Cell-Mediated Immune Responses to Human Papillomavirus....Pages 313-335
Papillomavirus Vaccines....Pages 337-369
Clinical Assessment, Therapies, New Tests, and Algorithms....Pages 371-386
Possible Worldwide Impact of Prevention of Human Papillomavirus Infection....Pages 387-413
Back Matter....Pages 415-419
The papillomaviruses have emerged as the best understood viruses that cause cancer in humans. This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes. Most importantly, human papillomavirus infection has been shown to be a crucial event in the development of several human cancers, most notably cervical cancer, a leading cause of cancer death in women. The Papillomaviruses is an ideal book for scientists, professionals, clinicians, and graduate students in the fields of immunology, infectious disease, virology, microbiology, cell biology, and cancer biology and research.
Content:
Front Matter....Pages i-xix
Principles of Human Tumor Virology....Pages 1-11
History of Papillomavirus Research....Pages 13-28
Phylogeny and Typing of Papillomaviruses....Pages 29-44
The Differentiation-Dependent Life Cycle of Human Papillomaviruses in Keratinocytes....Pages 45-67
Papillomavirus Structure and Assembly....Pages 69-88
Viral Entry and Receptors....Pages 89-107
Human Papillomavirus Transcription....Pages 109-144
DNA Replication of Papillomaviruses....Pages 145-174
Papillomavirus E5 Proteins....Pages 175-196
Human Papillomavirus E6 and E7 Oncogenes....Pages 197-252
In Vivo Models for the Study of Animal and Human Papillomaviruses....Pages 253-275
The Humoral Immune Response to Human Papillomavirus....Pages 277-312
Cell-Mediated Immune Responses to Human Papillomavirus....Pages 313-335
Papillomavirus Vaccines....Pages 337-369
Clinical Assessment, Therapies, New Tests, and Algorithms....Pages 371-386
Possible Worldwide Impact of Prevention of Human Papillomavirus Infection....Pages 387-413
Back Matter....Pages 415-419
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