Ebook: Bioarrays: From Basics to Diagnostics
- Tags: Medicinal Chemistry, Biotechnology, Human Genetics, Cell Biology
- Year: 2007
- Publisher: Humana Press
- Edition: 1
- Language: English
- pdf
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
This book provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections that create one well-integrated work – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
This book serves as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
This book provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections that create one well-integrated work – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
This book serves as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
Content:
Front Matter....Pages i-xviii
Front Matter....Pages 1-2
Investigation of Tumor Metastasis by Using cDNA Microarrays....Pages 3-16
From Tissue Samples to Tumor Markers....Pages 17-28
Experimental Design for Gene Expression Analysis....Pages 29-44
From Microarrays to Gene Networks....Pages 45-58
Front Matter....Pages 59-60
Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivity....Pages 61-82
Genomics to Identify Biomarkers of Normal Brain Aging....Pages 83-93
Gene Expression Profiling for Biomarker Discovery....Pages 95-106
Array-Based Comparative Genomic Hybridization....Pages 107-121
Regional Specialization of Endothelial Cells as Revealed by Genomic Analysis....Pages 123-134
Front Matter....Pages 135-136
Identification of Target Antigens in CNS Inflammation by Protein Array Technique....Pages 137-148
Differential Protein Expression, Protein Profiles of Human Gliomas, and Clinical Implications....Pages 149-173
Antibody-Based Microarrays....Pages 175-189
Glycoprofiling by DNA Sequencer-Aided Fluorophore-Assisted Carbohydrate Electrophoresis....Pages 191-200
High-Throughput Carbohydrate Microarray Technology....Pages 201-211
Front Matter....Pages 213-214
Microarrays and Blood Diagnostics....Pages 215-230
“Lab-on-a-Chip” Devices for Cellular Arrays Based on Dielectrophoresis....Pages 231-243
Genetic Disorders and Approaches to Their Prevention....Pages 245-261
Back Matter....Pages 263-269
This book provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections that create one well-integrated work – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
This book serves as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
Content:
Front Matter....Pages i-xviii
Front Matter....Pages 1-2
Investigation of Tumor Metastasis by Using cDNA Microarrays....Pages 3-16
From Tissue Samples to Tumor Markers....Pages 17-28
Experimental Design for Gene Expression Analysis....Pages 29-44
From Microarrays to Gene Networks....Pages 45-58
Front Matter....Pages 59-60
Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivity....Pages 61-82
Genomics to Identify Biomarkers of Normal Brain Aging....Pages 83-93
Gene Expression Profiling for Biomarker Discovery....Pages 95-106
Array-Based Comparative Genomic Hybridization....Pages 107-121
Regional Specialization of Endothelial Cells as Revealed by Genomic Analysis....Pages 123-134
Front Matter....Pages 135-136
Identification of Target Antigens in CNS Inflammation by Protein Array Technique....Pages 137-148
Differential Protein Expression, Protein Profiles of Human Gliomas, and Clinical Implications....Pages 149-173
Antibody-Based Microarrays....Pages 175-189
Glycoprofiling by DNA Sequencer-Aided Fluorophore-Assisted Carbohydrate Electrophoresis....Pages 191-200
High-Throughput Carbohydrate Microarray Technology....Pages 201-211
Front Matter....Pages 213-214
Microarrays and Blood Diagnostics....Pages 215-230
“Lab-on-a-Chip” Devices for Cellular Arrays Based on Dielectrophoresis....Pages 231-243
Genetic Disorders and Approaches to Their Prevention....Pages 245-261
Back Matter....Pages 263-269
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