Ebook: Rb and Tumorigenesis
Author: Maurizio Fanciulli Ph.D. (auth.)
- Tags: Cell Biology, Molecular Medicine, Immunology
- Series: Molecular Biology Intelligence Unit
- Year: 2006
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle. This book will interest cell biologists, graduate students and researchers.
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle. This book will interest cell biologists, graduate students and researchers.
Content:
Front Matter....Pages i-ix
RB as a Positive Transcriptional Regulator during Epithelial Differentiation....Pages 1-10
pRb in the Differentiation of Normal and Neoplastic Cells....Pages 11-19
Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein....Pages 20-36
New Insights into Transcriptional Regulation by Rb....Pages 37-45
Regulation of Rb Function by Noncyclin Dependent Kinases....Pages 46-58
Diverse Regulatory Functions of the E2F Family of Transcription Factors....Pages 59-72
Regulation of E2F-Responsive Genes through Histone Modifications....Pages 73-80
Emerging Roles for the Retinoblastoma Gene Family....Pages 81-105
Rb and Cellular Differentiation....Pages 106-117
Back Matter....Pages 119-121
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle. This book will interest cell biologists, graduate students and researchers.
Content:
Front Matter....Pages i-ix
RB as a Positive Transcriptional Regulator during Epithelial Differentiation....Pages 1-10
pRb in the Differentiation of Normal and Neoplastic Cells....Pages 11-19
Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein....Pages 20-36
New Insights into Transcriptional Regulation by Rb....Pages 37-45
Regulation of Rb Function by Noncyclin Dependent Kinases....Pages 46-58
Diverse Regulatory Functions of the E2F Family of Transcription Factors....Pages 59-72
Regulation of E2F-Responsive Genes through Histone Modifications....Pages 73-80
Emerging Roles for the Retinoblastoma Gene Family....Pages 81-105
Rb and Cellular Differentiation....Pages 106-117
Back Matter....Pages 119-121
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