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27.01.2024
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Recently, expectations of the potential of regenerative medicine have risen because of the exciting results obtained in various areas of research. This book contains contributions from leading researchers in the field who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main areas -- reproduction and the brain -- described from molecular, cellular, in vivo and clinical perspectives.




Recently, expectations of the potential of regenerative medicine have risen because of the exciting results obtained in various areas of research. This book contains contributions from leading researchers in the field who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main areas -- reproduction and the brain -- described from molecular, cellular, in vivo and clinical perspectives.




Recently, expectations of the potential of regenerative medicine have risen because of the exciting results obtained in various areas of research. This book contains contributions from leading researchers in the field who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main areas -- reproduction and the brain -- described from molecular, cellular, in vivo and clinical perspectives.


Content:
Front Matter....Pages I-XIV
What Is a Stem Cell Niche?....Pages 1-14
New Strategy for Comprehensive Analysis of Gene Functions in Embryonic Stem cells....Pages 15-22
Paternal Dual Barrier by Ifg2-H19 and Dlk1-Gtl2 to Parthenogenesis in Mice....Pages 23-33
Cell-Cell Fusion as a Means to Establish Pluripotency....Pages 35-45
Toward Reprogramming Cells to Pluripotency....Pages 47-67
Molecular Switches and Developmental Potential of Adult Stem Cells....Pages 69-79
Adult Small Intestinal Stem Cells: Identification, Location, Characteristics, and Clinical Applications....Pages 81-98
Tracking Stem Cells In Vivo....Pages 99-109
Establishment of Nuclear Transfer Embryonic Stem Cell Lines from Adult Somatic Cells by Nuclear Transfer and Its Application....Pages 111-123
Derivation of Germ Cells from Embryonic Stem Cells....Pages 125-142
Germline Recruitment in Mice: A Genetic Program for Epigenetic Reprogramming....Pages 143-174
Transplantation of Germ Line Stem Cells for the Study and Manipulation of Spermatogenesis....Pages 175-193
Progenitor Cell-Based Myelination as a Model for Cell-Based Therapy of the Central Nervous System....Pages 195-213
Adult Neural Stem Cells and Central Nervous System Repair....Pages 215-228
Stem Cell Therapy for Parkinson’s Disease....Pages 229-244
Back Matter....Pages 245-249


Recently, expectations of the potential of regenerative medicine have risen because of the exciting results obtained in various areas of research. This book contains contributions from leading researchers in the field who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main areas -- reproduction and the brain -- described from molecular, cellular, in vivo and clinical perspectives.


Content:
Front Matter....Pages I-XIV
What Is a Stem Cell Niche?....Pages 1-14
New Strategy for Comprehensive Analysis of Gene Functions in Embryonic Stem cells....Pages 15-22
Paternal Dual Barrier by Ifg2-H19 and Dlk1-Gtl2 to Parthenogenesis in Mice....Pages 23-33
Cell-Cell Fusion as a Means to Establish Pluripotency....Pages 35-45
Toward Reprogramming Cells to Pluripotency....Pages 47-67
Molecular Switches and Developmental Potential of Adult Stem Cells....Pages 69-79
Adult Small Intestinal Stem Cells: Identification, Location, Characteristics, and Clinical Applications....Pages 81-98
Tracking Stem Cells In Vivo....Pages 99-109
Establishment of Nuclear Transfer Embryonic Stem Cell Lines from Adult Somatic Cells by Nuclear Transfer and Its Application....Pages 111-123
Derivation of Germ Cells from Embryonic Stem Cells....Pages 125-142
Germline Recruitment in Mice: A Genetic Program for Epigenetic Reprogramming....Pages 143-174
Transplantation of Germ Line Stem Cells for the Study and Manipulation of Spermatogenesis....Pages 175-193
Progenitor Cell-Based Myelination as a Model for Cell-Based Therapy of the Central Nervous System....Pages 195-213
Adult Neural Stem Cells and Central Nervous System Repair....Pages 215-228
Stem Cell Therapy for Parkinson’s Disease....Pages 229-244
Back Matter....Pages 245-249
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