Ebook: NF-κB/Rel Transcription Factor Family
- Tags: Cell Biology, Immunology, Pharmacology/Toxicology, Microbiology
- Series: Molecular Biology Intelligence Unit
- Year: 2006
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Content:
Front Matter....Pages i-xix
Structural Analysis of NF-?B and I?B Proteins....Pages 1-11
NF-?B Signal Transduction by IKK Complexes....Pages 12-25
Receptors and Adaptors for NF-?B Signaling....Pages 26-40
Cellular Dynamics of NF-?B Associated Proteins....Pages 41-50
NF-?B in Lymphopoiesis....Pages 51-69
NF-?B and Immune Cell Effector Functions....Pages 70-83
Roles of NF-?B in Autoimmunity....Pages 84-90
The Central Role of NF-?B in the Regulation of Immunity to Infection....Pages 91-111
Molecular Basis of Oncogenesis by NF-?B....Pages 112-130
NF-?B in Human Cancers....Pages 131-146
NF-?B in Neurons....Pages 147-161
Inhibitors of NF-?B Activity....Pages 162-178
Back Matter....Pages 179-185
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Content:
Front Matter....Pages i-xix
Structural Analysis of NF-?B and I?B Proteins....Pages 1-11
NF-?B Signal Transduction by IKK Complexes....Pages 12-25
Receptors and Adaptors for NF-?B Signaling....Pages 26-40
Cellular Dynamics of NF-?B Associated Proteins....Pages 41-50
NF-?B in Lymphopoiesis....Pages 51-69
NF-?B and Immune Cell Effector Functions....Pages 70-83
Roles of NF-?B in Autoimmunity....Pages 84-90
The Central Role of NF-?B in the Regulation of Immunity to Infection....Pages 91-111
Molecular Basis of Oncogenesis by NF-?B....Pages 112-130
NF-?B in Human Cancers....Pages 131-146
NF-?B in Neurons....Pages 147-161
Inhibitors of NF-?B Activity....Pages 162-178
Back Matter....Pages 179-185
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