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Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.

This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.




Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.

This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.




Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.

This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.


Content:
Front Matter....Pages I-XIX
Front Matter....Pages 1-1
Gas Chromatography Mass Spectrometry....Pages 3-20
Current Status and Forward Looking Thoughts on LC/MS Metabolomics....Pages 21-32
Plant Metabolomics Strategies Based upon Quadrupole Time of Flight Mass Spectrometry (QTOF-MS)....Pages 33-48
Capillary HPLC....Pages 49-63
Capillary HPLC Coupled to Electrospray Ionization Quadrupole Time-of-flight Mass Spectrometry....Pages 65-79
NMR Spectroscopy in Plant Metabolomics....Pages 81-91
Hetero-nuclear NMR-based Metabolomics....Pages 93-101
Front Matter....Pages 103-103
Bioinformatics Approaches to Integrate Metabolomics and Other Systems Biology Data....Pages 105-115
Chemometrics in Metabolomics — An Introduction....Pages 117-128
Map Editor for the Atomic Reconstruction of Metabolism (ARM)....Pages 129-139
AraCyc: Overview of an Arabidopsis Metabolism Database and its Applications for Plant Research....Pages 141-154
KaPPA-View: A Tool for Integrating Transcriptomic and Metabolomic Data on Plant Metabolic Pathway Maps....Pages 155-163
KNApSAcK: A Comprehensive Species-Metabolite Relationship Database....Pages 165-181
Front Matter....Pages 183-183
Systems Biology: A Renaissance of the Top-down Approach for Plant Analysis....Pages 185-198
Systems-based Analysis of Plant Metabolism by Integration of Metabolomics with Transcriptomics....Pages 199-209
Targeted Profiling of Fatty Acids and Related Metabolites....Pages 211-228
Metabolic Profiling and Quantification of Carotenoids and Related Isoprenoids in Crop Plants....Pages 229-242
Metabolomics and Gene Identification in Plant Natural Product Pathways....Pages 243-259
Metabolomic Analysis of Catharanthus roseus Using NMR and Principal Component Analysis....Pages 261-276
Metabolomics of Plant Secondary Compounds: Profiling of Catharanthus Cell Cultures....Pages 277-289
Front Matter....Pages 183-183
The Taxus Metabolome and the Elucidation of the Taxol® Biosynthetic Pathway in Cell Suspension Cultures....Pages 291-309
The Use of Non-targeted Metabolomics in Plant Science....Pages 311-325
Plant Metabolite Profiling for Industrial Applications....Pages 327-339
Back Matter....Pages 341-350


Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.

This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.


Content:
Front Matter....Pages I-XIX
Front Matter....Pages 1-1
Gas Chromatography Mass Spectrometry....Pages 3-20
Current Status and Forward Looking Thoughts on LC/MS Metabolomics....Pages 21-32
Plant Metabolomics Strategies Based upon Quadrupole Time of Flight Mass Spectrometry (QTOF-MS)....Pages 33-48
Capillary HPLC....Pages 49-63
Capillary HPLC Coupled to Electrospray Ionization Quadrupole Time-of-flight Mass Spectrometry....Pages 65-79
NMR Spectroscopy in Plant Metabolomics....Pages 81-91
Hetero-nuclear NMR-based Metabolomics....Pages 93-101
Front Matter....Pages 103-103
Bioinformatics Approaches to Integrate Metabolomics and Other Systems Biology Data....Pages 105-115
Chemometrics in Metabolomics — An Introduction....Pages 117-128
Map Editor for the Atomic Reconstruction of Metabolism (ARM)....Pages 129-139
AraCyc: Overview of an Arabidopsis Metabolism Database and its Applications for Plant Research....Pages 141-154
KaPPA-View: A Tool for Integrating Transcriptomic and Metabolomic Data on Plant Metabolic Pathway Maps....Pages 155-163
KNApSAcK: A Comprehensive Species-Metabolite Relationship Database....Pages 165-181
Front Matter....Pages 183-183
Systems Biology: A Renaissance of the Top-down Approach for Plant Analysis....Pages 185-198
Systems-based Analysis of Plant Metabolism by Integration of Metabolomics with Transcriptomics....Pages 199-209
Targeted Profiling of Fatty Acids and Related Metabolites....Pages 211-228
Metabolic Profiling and Quantification of Carotenoids and Related Isoprenoids in Crop Plants....Pages 229-242
Metabolomics and Gene Identification in Plant Natural Product Pathways....Pages 243-259
Metabolomic Analysis of Catharanthus roseus Using NMR and Principal Component Analysis....Pages 261-276
Metabolomics of Plant Secondary Compounds: Profiling of Catharanthus Cell Cultures....Pages 277-289
Front Matter....Pages 183-183
The Taxus Metabolome and the Elucidation of the Taxol® Biosynthetic Pathway in Cell Suspension Cultures....Pages 291-309
The Use of Non-targeted Metabolomics in Plant Science....Pages 311-325
Plant Metabolite Profiling for Industrial Applications....Pages 327-339
Back Matter....Pages 341-350
....
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