Ebook: Human Mitochondrial DNA and the Evolution of Homo sapiens
- Tags: Human Genetics, Cell Biology, Evolutionary Biology, Anthropology, Biochemistry general
- Series: Nucleic Acids and Molecular Biology 18
- Year: 2006
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.
Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.
Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.
Content:
Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Mitochondrial DNA in Homo Sapiens ....Pages 3-15
The Transmission and Segregation of Mitochondrial DNA in Homo Sapiens ....Pages 17-29
Numts Revisited....Pages 31-46
Estimation of Mutation Rates and Coalescence Times: Some Caveats....Pages 47-90
Postmortem Damage of Mitochondrial DNA....Pages 91-115
Lab-Specific Mutation Processes....Pages 117-146
Front Matter....Pages 147-147
The World mtDNA Phylogeny....Pages 149-179
The Pioneer Settlement of Modern Humans in Asia....Pages 181-199
Ancient DNA and the Neanderthals....Pages 201-224
A Model for the Dispersal of Modern Humans out of Africa....Pages 225-265
Back Matter....Pages 267-271
Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.
Content:
Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Mitochondrial DNA in Homo Sapiens ....Pages 3-15
The Transmission and Segregation of Mitochondrial DNA in Homo Sapiens ....Pages 17-29
Numts Revisited....Pages 31-46
Estimation of Mutation Rates and Coalescence Times: Some Caveats....Pages 47-90
Postmortem Damage of Mitochondrial DNA....Pages 91-115
Lab-Specific Mutation Processes....Pages 117-146
Front Matter....Pages 147-147
The World mtDNA Phylogeny....Pages 149-179
The Pioneer Settlement of Modern Humans in Asia....Pages 181-199
Ancient DNA and the Neanderthals....Pages 201-224
A Model for the Dispersal of Modern Humans out of Africa....Pages 225-265
Back Matter....Pages 267-271
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