Ebook: DNA Repair and Human Disease
- Tags: Human Genetics, Medical Microbiology, Cell Biology
- Series: Medical Intelligence Unit
- Year: 2006
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
Content:
Front Matter....Pages i-xii
Human Premature Aging Disorders and Dysfunction of DNA Repair....Pages 1-19
DNA Repair Aspects for RecQ Helicase Disorders....Pages 20-29
Trichothiodystrophy....Pages 30-46
Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair....Pages 47-60
Radiosensitivity of Cells Derived from Down Syndrome Patients....Pages 61-66
The Fanconi Anemia/BRCA Pathway....Pages 67-81
Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?....Pages 82-97
Mechanisms of DNA Damage and Repair in Alzheimer Disease....Pages 98-113
Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells....Pages 114-127
Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients....Pages 128-146
Back Matter....Pages 147-150
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
Content:
Front Matter....Pages i-xii
Human Premature Aging Disorders and Dysfunction of DNA Repair....Pages 1-19
DNA Repair Aspects for RecQ Helicase Disorders....Pages 20-29
Trichothiodystrophy....Pages 30-46
Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair....Pages 47-60
Radiosensitivity of Cells Derived from Down Syndrome Patients....Pages 61-66
The Fanconi Anemia/BRCA Pathway....Pages 67-81
Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?....Pages 82-97
Mechanisms of DNA Damage and Repair in Alzheimer Disease....Pages 98-113
Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells....Pages 114-127
Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients....Pages 128-146
Back Matter....Pages 147-150
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