Ebook: The Promises and Challenges of Regenerative Medicine
- Tags: Cell Biology, Developmental Biology, Neurology, Cardiology
- Series: Ernst Schering Research Foundation Workshop 54
- Year: 2005
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.
The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.
The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.
Content:
Front Matter....Pages I-XI
Melanocyte System for Studying Stem Cell Niche....Pages 1-13
Establishment and Manipulation of Monkey and Human Embryonic Stem Cell Lines for Biomedical Research....Pages 15-26
Human Embryonic Stem Cell Derivation and Directed Differentiation....Pages 27-44
In Search of the Elusive Epidermal Stem Cell....Pages 45-62
Corneal Cells for Regeneration....Pages 63-83
Polycomb Gene Product Bmi-1 Regulates Stem Cell Self-Renewal....Pages 85-100
Directed Differentiation of Neural and Sensory Tissues from Embryonic Stem Cells In Vitro....Pages 101-109
Stem Cell Biology for Vascular Regeneration....Pages 111-129
Back Matter....Pages 131-136
The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.
Content:
Front Matter....Pages I-XI
Melanocyte System for Studying Stem Cell Niche....Pages 1-13
Establishment and Manipulation of Monkey and Human Embryonic Stem Cell Lines for Biomedical Research....Pages 15-26
Human Embryonic Stem Cell Derivation and Directed Differentiation....Pages 27-44
In Search of the Elusive Epidermal Stem Cell....Pages 45-62
Corneal Cells for Regeneration....Pages 63-83
Polycomb Gene Product Bmi-1 Regulates Stem Cell Self-Renewal....Pages 85-100
Directed Differentiation of Neural and Sensory Tissues from Embryonic Stem Cells In Vitro....Pages 101-109
Stem Cell Biology for Vascular Regeneration....Pages 111-129
Back Matter....Pages 131-136
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