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Members of the phylum Echinodermata are among the most familiar marine invertebrates. Forms such as the sea star have become virtually a symbol of sea life. Used in ancient oriental medicine as a source of bioactive compounds, sea cucumbers, sea stars and sea urchins are now used for the extraction and purification of cytotoxic, haemolytic, antiviral, antifungal, antifouling, antimicrobial and even anti-tumoural activities. In addition, of the five extant classes, sea urchins and sea cucumbers are important economic resources for current fishery and aquaculture. Molecular and cell biological techniques described in this book are, on the one hand, indicative of the improvements made over the years and, on the other, stress the need of their further exploitation for the sustainable production of bioactive compounds and their application in biomedicine.




Members of the phylum Echinodermata are among the most familiar marine invertebrates. Forms such as the sea star have become virtually a symbol of sea life. Used in ancient oriental medicine as a source of bioactive compounds, sea cucumbers, sea stars and sea urchins are now used for the extraction and purification of cytotoxic, haemolytic, antiviral, antifungal, antifouling, antimicrobial and even anti-tumoural activities. In addition, of the five extant classes, sea urchins and sea cucumbers are important economic resources for current fishery and aquaculture. Molecular and cell biological techniques described in this book are, on the one hand, indicative of the improvements made over the years and, on the other, stress the need of their further exploitation for the sustainable production of bioactive compounds and their application in biomedicine.




Members of the phylum Echinodermata are among the most familiar marine invertebrates. Forms such as the sea star have become virtually a symbol of sea life. Used in ancient oriental medicine as a source of bioactive compounds, sea cucumbers, sea stars and sea urchins are now used for the extraction and purification of cytotoxic, haemolytic, antiviral, antifungal, antifouling, antimicrobial and even anti-tumoural activities. In addition, of the five extant classes, sea urchins and sea cucumbers are important economic resources for current fishery and aquaculture. Molecular and cell biological techniques described in this book are, on the one hand, indicative of the improvements made over the years and, on the other, stress the need of their further exploitation for the sustainable production of bioactive compounds and their application in biomedicine.


Content:
Front Matter....Pages I-XXIII
Are Echinoderms of Interest to Biotechnology?....Pages 1-6
Cell Adhesion and Communication: A Lesson from Echinoderm Embryos for the Exploitation of New Therapeutic Tools....Pages 7-44
Cell Signalling During Sea Urchin Development: A Model for Assessing Toxicity of Environmental Contaminants....Pages 45-70
Echinoderm Reactive Oxygen Species (ROS) Production Measured by Peroxidase, Luminol-Enhanced Chemiluminescence (PLCL) as an Immunotoxicological Tool....Pages 71-83
Monitoring Chemical and Physical Stress Using Sea Urchin Immune Cells....Pages 85-110
DNA Damage and Developmental Defects After Exposure to UV and Heavy Metals in Sea Urchin Cells and Embryos Compared to Other Invertebrates....Pages 111-137
Echinoderms: Their Culture and Bioactive Compounds....Pages 139-165
Regenerative Response and Endocrine Disrupters in Crinoid Echinoderms: An Old Experimental Model, a New Ecotoxicological Test....Pages 167-200
Echinoderm Adhesive Secretions: From Experimental Characterization to Biotechnological Applications....Pages 201-220
Mutable Collagenous Tissue: Overview and Biotechnological Perspective....Pages 221-250
Bioresources from Echinoderms....Pages 251-266
Back Matter....Pages 267-277


Members of the phylum Echinodermata are among the most familiar marine invertebrates. Forms such as the sea star have become virtually a symbol of sea life. Used in ancient oriental medicine as a source of bioactive compounds, sea cucumbers, sea stars and sea urchins are now used for the extraction and purification of cytotoxic, haemolytic, antiviral, antifungal, antifouling, antimicrobial and even anti-tumoural activities. In addition, of the five extant classes, sea urchins and sea cucumbers are important economic resources for current fishery and aquaculture. Molecular and cell biological techniques described in this book are, on the one hand, indicative of the improvements made over the years and, on the other, stress the need of their further exploitation for the sustainable production of bioactive compounds and their application in biomedicine.


Content:
Front Matter....Pages I-XXIII
Are Echinoderms of Interest to Biotechnology?....Pages 1-6
Cell Adhesion and Communication: A Lesson from Echinoderm Embryos for the Exploitation of New Therapeutic Tools....Pages 7-44
Cell Signalling During Sea Urchin Development: A Model for Assessing Toxicity of Environmental Contaminants....Pages 45-70
Echinoderm Reactive Oxygen Species (ROS) Production Measured by Peroxidase, Luminol-Enhanced Chemiluminescence (PLCL) as an Immunotoxicological Tool....Pages 71-83
Monitoring Chemical and Physical Stress Using Sea Urchin Immune Cells....Pages 85-110
DNA Damage and Developmental Defects After Exposure to UV and Heavy Metals in Sea Urchin Cells and Embryos Compared to Other Invertebrates....Pages 111-137
Echinoderms: Their Culture and Bioactive Compounds....Pages 139-165
Regenerative Response and Endocrine Disrupters in Crinoid Echinoderms: An Old Experimental Model, a New Ecotoxicological Test....Pages 167-200
Echinoderm Adhesive Secretions: From Experimental Characterization to Biotechnological Applications....Pages 201-220
Mutable Collagenous Tissue: Overview and Biotechnological Perspective....Pages 221-250
Bioresources from Echinoderms....Pages 251-266
Back Matter....Pages 267-277
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