Ebook: Selective Sweep
- Tags: Cell Biology
- Series: Molecular Biology Intelligence Unit
- Year: 2005
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.
Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.
Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.
Content:
Front Matter....Pages i-viii
Inferring Evolutionary History through Inter- and Intraspecific DNA Sequence Comparison....Pages 1-12
Rapid Evolution of Sex-Related Genes....Pages 13-21
Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila ....Pages 22-33
Detecting Selective Sweeps with Haplotype Tests....Pages 34-54
A Novel Test Statistic for the Identification of Local Selective Sweeps Based on Microsatellite Gene Diversity....Pages 55-64
Detecting Hitchhiking from Patterns of DNA Polymorphism....Pages 65-77
Periodic Selection and Ecological Diversity in Bacteria....Pages 78-93
Distribution and Abundance of Polymorphism in the Malaria Genome....Pages 94-103
Selective Sweeps in Structured Populations—Empirical Evidence and Theoretical Studies....Pages 104-117
Back Matter....Pages 119-121
Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.
Content:
Front Matter....Pages i-viii
Inferring Evolutionary History through Inter- and Intraspecific DNA Sequence Comparison....Pages 1-12
Rapid Evolution of Sex-Related Genes....Pages 13-21
Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila ....Pages 22-33
Detecting Selective Sweeps with Haplotype Tests....Pages 34-54
A Novel Test Statistic for the Identification of Local Selective Sweeps Based on Microsatellite Gene Diversity....Pages 55-64
Detecting Hitchhiking from Patterns of DNA Polymorphism....Pages 65-77
Periodic Selection and Ecological Diversity in Bacteria....Pages 78-93
Distribution and Abundance of Polymorphism in the Malaria Genome....Pages 94-103
Selective Sweeps in Structured Populations—Empirical Evidence and Theoretical Studies....Pages 104-117
Back Matter....Pages 119-121
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