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For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.




For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.


For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.
Content:
Front Matter....Pages i-xiii
Antibiotic Policies—A Historical Perspective....Pages 1-14
Guideline Implementation: It is Not Impossible....Pages 15-22
UK Guidelines: Methodology and Standards of Care....Pages 23-35
Pneumonia Guidelines in Practice....Pages 37-66
Collecting, Converting, and Making Sense of Hospital Antimicrobial Consumption Data....Pages 67-74
How Do Measurements of Antibiotic Consumption Relate to Antibiotic Resistance?....Pages 75-103
Quantitative Measurement of Antibiotic Use....Pages 105-118
Benchmarking....Pages 119-131
Experiences with Antimicrobial Utilisation Surveillance and Benchmarking....Pages 133-158
Interventions to Optimise Antibiotic Prescribing in Hospitals: The UK Approach....Pages 159-183
Improving Prescribing in Surgical Prophylaxis....Pages 185-195
Audits for Monitoring the Quality of Antimicrobial Prescriptions....Pages 197-226
Multidisciplinary Antimicrobial Management Teams and the Role of the Pharmacist in Management of Infection....Pages 227-249
Antibiotic Policy—Slovenian Experiences....Pages 251-260
Intensive Care Unit....Pages 261-279
The Real Cost of MRSA....Pages 281-309
Antifungal Agents: Resistance and Rational Use....Pages 311-330
Strategies for the Rational Use of Antivirals....Pages 331-349
Disinfection Policies in Hospitals and the Community....Pages 351-366
The Evolution of Antibiotic Resistance within Patients....Pages 367-385
Impact of Pharmacodynamics on Dosing Schedules: Optimizing Efficacy, Reducing Resistance, and Detection of Emergence of Resistance....Pages 387-407
Types of Surveillance Data and Meaningful Indicators for Reporting Antimicrobial Resistance....Pages 409-420
Data Mining to Discover Emerging Patterns of Antimicrobic Resistance....Pages 421-446
Applications of Time-series Analysis to Antibiotic Resistance and Consumption Data....Pages 447-463
Biocide Use and Antibiotic Resistance....Pages 465-489
Interventions to Improve Antibiotic Prescribing in the Community....Pages 491-530
Education of Patients and Professionals....Pages 531-543
The Influence of National Policies on Antibiotic Prescribing....Pages 545-566
Antibiotic Use in the Community....Pages 567-581
Antibiotic Use in the Community: The French Experience....Pages 583-592
Antibiotic Policies in Developing Countries....Pages 593-616
Antimicrobial Resistance and its Containment in Developing Countries....Pages 617-647
Antibiotic Use in Animals—Policies and Control Measures Around Europe....Pages 649-672
The Pharmaceutical Company Approach to Antibiotic Policies....Pages 673-699
Antibiotic Use—Ecological Issues and Required Actions....Pages 701-715
Back Matter....Pages 717-766


For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.
Content:
Front Matter....Pages i-xiii
Antibiotic Policies—A Historical Perspective....Pages 1-14
Guideline Implementation: It is Not Impossible....Pages 15-22
UK Guidelines: Methodology and Standards of Care....Pages 23-35
Pneumonia Guidelines in Practice....Pages 37-66
Collecting, Converting, and Making Sense of Hospital Antimicrobial Consumption Data....Pages 67-74
How Do Measurements of Antibiotic Consumption Relate to Antibiotic Resistance?....Pages 75-103
Quantitative Measurement of Antibiotic Use....Pages 105-118
Benchmarking....Pages 119-131
Experiences with Antimicrobial Utilisation Surveillance and Benchmarking....Pages 133-158
Interventions to Optimise Antibiotic Prescribing in Hospitals: The UK Approach....Pages 159-183
Improving Prescribing in Surgical Prophylaxis....Pages 185-195
Audits for Monitoring the Quality of Antimicrobial Prescriptions....Pages 197-226
Multidisciplinary Antimicrobial Management Teams and the Role of the Pharmacist in Management of Infection....Pages 227-249
Antibiotic Policy—Slovenian Experiences....Pages 251-260
Intensive Care Unit....Pages 261-279
The Real Cost of MRSA....Pages 281-309
Antifungal Agents: Resistance and Rational Use....Pages 311-330
Strategies for the Rational Use of Antivirals....Pages 331-349
Disinfection Policies in Hospitals and the Community....Pages 351-366
The Evolution of Antibiotic Resistance within Patients....Pages 367-385
Impact of Pharmacodynamics on Dosing Schedules: Optimizing Efficacy, Reducing Resistance, and Detection of Emergence of Resistance....Pages 387-407
Types of Surveillance Data and Meaningful Indicators for Reporting Antimicrobial Resistance....Pages 409-420
Data Mining to Discover Emerging Patterns of Antimicrobic Resistance....Pages 421-446
Applications of Time-series Analysis to Antibiotic Resistance and Consumption Data....Pages 447-463
Biocide Use and Antibiotic Resistance....Pages 465-489
Interventions to Improve Antibiotic Prescribing in the Community....Pages 491-530
Education of Patients and Professionals....Pages 531-543
The Influence of National Policies on Antibiotic Prescribing....Pages 545-566
Antibiotic Use in the Community....Pages 567-581
Antibiotic Use in the Community: The French Experience....Pages 583-592
Antibiotic Policies in Developing Countries....Pages 593-616
Antimicrobial Resistance and its Containment in Developing Countries....Pages 617-647
Antibiotic Use in Animals—Policies and Control Measures Around Europe....Pages 649-672
The Pharmaceutical Company Approach to Antibiotic Policies....Pages 673-699
Antibiotic Use—Ecological Issues and Required Actions....Pages 701-715
Back Matter....Pages 717-766
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