Ebook: Engineering and Manufacturing for Biotechnology

Early integration is the key to success in industrial biotechnology. This is as true when a selected wild-type organism is put to work as when an organism is engineered for a purpose.
The present volume Engineering and Manufacturing for Biotechnology took advantage of the 9th European Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999): in the topics handled and in the expertise of the contributors, the engineering science symposia of this congress offered just what was needed to cover the important topic of integration of process engineering and biological research.
The editors have solicited a number of outstanding contributions to illustrate the intimate interaction between productive organisms and the numerous processing steps running from the initial inoculation to the packaged product. Upstream processing of the feed streams, selection of medium components, product harvesting, downstream processing, and product conditioning are just a few major steps. Each step imposes a number of important choices. Every choice is to be balanced against time to market, profitability, safety, and ecology.

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Early integration is the key to success in industrial biotechnology. This is as true when a selected wild-type organism is put to work as when an organism is engineered for a purpose.
The present volume Engineering and Manufacturing for Biotechnology took advantage of the 9th European Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999): in the topics handled and in the expertise of the contributors, the engineering science symposia of this congress offered just what was needed to cover the important topic of integration of process engineering and biological research.
The editors have solicited a number of outstanding contributions to illustrate the intimate interaction between productive organisms and the numerous processing steps running from the initial inoculation to the packaged product. Upstream processing of the feed streams, selection of medium components, product harvesting, downstream processing, and product conditioning are just a few major steps. Each step imposes a number of important choices. Every choice is to be balanced against time to market, profitability, safety, and ecology.

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Early integration is the key to success in industrial biotechnology. This is as true when a selected wild-type organism is put to work as when an organism is engineered for a purpose.
The present volume Engineering and Manufacturing for Biotechnology took advantage of the 9th European Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999): in the topics handled and in the expertise of the contributors, the engineering science symposia of this congress offered just what was needed to cover the important topic of integration of process engineering and biological research.
The editors have solicited a number of outstanding contributions to illustrate the intimate interaction between productive organisms and the numerous processing steps running from the initial inoculation to the packaged product. Upstream processing of the feed streams, selection of medium components, product harvesting, downstream processing, and product conditioning are just a few major steps. Each step imposes a number of important choices. Every choice is to be balanced against time to market, profitability, safety, and ecology.
Content:
Front Matter....Pages i-18
Front Matter....Pages 19-19
Pretreatment Processes of Molasses for the Utilization in Fermentation Processes....Pages 21-28
Lactic Acdi Fermentation of Hemicellulose Liquors and Their Activated Carbon Pretreatments....Pages 29-38
Enzymic Solubilisation of Proteins from Tropical Tuna Using Alcalase and Some Biological Properties of the Hydrolysates....Pages 39-50
Influence of the Experimental Conditions on the Hydrolysis Process in Fish Hydrolysates....Pages 51-58
Front Matter....Pages 59-59
Mathematical Modelling of Microbial Processes-Motivation and Means....Pages 61-75
Macroscopic Modelling of Bioprocesses with a View to Engineering Applications....Pages 77-109
A Model Discrimination Approach for Data Analysis and Experimental Design....Pages 111-128
Model Based Sequential Experimental Design for Bioprocess Optimisation — an Overview....Pages 129-141
Front Matter....Pages 143-156
Crossflow Ultrafiltration of Bacillus Licheniformis Fermentation Medium to Separate Protease Enzymes....Pages 157-167
Front Matter....Pages 169-169
Evaluating KLa During Fermentation Using Many Methods Simultaneously....Pages 171-179
Respiration Quotient: Estimation During Batch Cultivation in Bicarbonate Buffered Media....Pages 181-181
Fermentation Phase Detection Using Fuzzy Clustering Techniques and Neural Networks for Improved Control....Pages 183-201
Simulation, Design and Model Based Predictive Control of Photobioreactors....Pages 203-216
Front Matter....Pages 217-226
Bioreactors for Space: Biotechnology of the Next Century....Pages 227-238
Front Matter....Pages 239-239
State of the Art Developments in Immobilised Yeast Technology for Brewing....Pages 241-251
Immobilized Yeast Bioreactor Systems for Brewing—Recent Achievements....Pages 253-253
New Matrices and Bioencapsulation Processes....Pages 255-276
Front Matter....Pages 277-292
Industrial Downstream Processing....Pages 293-307
Front Matter....Pages 309-309
Separation of &?-Lactalbumin and &?-Lactoglobulin by Preparative Chromatography Using Simulated Moving Beds....Pages 311-324
High-Speed Pectic Enzyme Fractionation by Immobilised Metal Ion Affinity Membranes....Pages 309-309
Front Matter....Pages 325-337
Economic Benefits of the Application of Biotechnology-Examples....Pages 339-349
Enzyme Stability and Stabilisation: Applications and Case Studies....Pages 351-351
Improvements of Enzyme Stability and Specificity by Genetic Engineering....Pages 353-360
An Approach to Desiccation-Tolerant Bacteria in Starter Culture Production....Pages 361-376
Biotechnological Research and the Dairy Industry:....Pages 377-382
Immobilised Cell Technology in Winery and Fruit Wine Production....Pages 383-398
A New Polysaccharide Derived from Plant Rhizosheree: Production, Purification and Physico-Chemical Properties....Pages 399-412
Initiation, Growth and Immobilisation of Cell Cultures of Taxus spp. for Paclitaxel Production....Pages 413-421
Effective Biofuel Production by an Intelligent Bioreactor....Pages 423-428
Front Matter....Pages 429-448
Translating European Biotech into us Patents Do’s, Don’ts, & Costs....Pages 449-455
Back Matter....Pages 457-457
....Pages 459-486