Ebook: Disease-modifying Therapy in Vasculitides

Especially the past two decades have seen renewed interest in the vasculitides. In this volume an international expert group presents the current state of knowledge and concentrates on principles of immune modulating therapy. Drawing from their work in rheumatology, nephrology, internal medicine, connective tissue disease and clinical immunology, they present new concepts in classificiation, diagnosis and pathophysiology of the vasculitides. Evidence from experimental and clinical trials is reviewed, as well as the outlook for further research.

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Content:
Front Matter....Pages i-ix
Systemic vasculitides, an introduction....Pages 1-19
Standard therapeutic regimens for vasculitis....Pages 21-40
Tumor necrosis factor (TNF) inhibition in the treatment of vasculitis....Pages 41-63
Methotrexate as an alternative to classic immunosuppressive therapies....Pages 65-80
Intravenous immunoglobulin as immuno-modifying treatment....Pages 81-111
T-cell directed treatment: anti-thymocyte globulin....Pages 113-123
New immunosuppressants: mycophenolate mofetil and 15-deoxyspergualin....Pages 125-146
Interferon-? for the treatment of virus-related systemic vasculitides....Pages 147-157
Autologous stem cell therapy for systemic vasculitis....Pages 159-180
Prevention of relapsing disease in anti-neutrophil cytoplasmic antibody related necrotizing small-vessel vasculitis: the role for autoantibody guided and anti-bacterial treatment....Pages 181-199
Back Matter....Pages 201-206

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Content:
Front Matter....Pages i-ix
Systemic vasculitides, an introduction....Pages 1-19
Standard therapeutic regimens for vasculitis....Pages 21-40
Tumor necrosis factor (TNF) inhibition in the treatment of vasculitis....Pages 41-63
Methotrexate as an alternative to classic immunosuppressive therapies....Pages 65-80
Intravenous immunoglobulin as immuno-modifying treatment....Pages 81-111
T-cell directed treatment: anti-thymocyte globulin....Pages 113-123
New immunosuppressants: mycophenolate mofetil and 15-deoxyspergualin....Pages 125-146
Interferon-? for the treatment of virus-related systemic vasculitides....Pages 147-157
Autologous stem cell therapy for systemic vasculitis....Pages 159-180
Prevention of relapsing disease in anti-neutrophil cytoplasmic antibody related necrotizing small-vessel vasculitis: the role for autoantibody guided and anti-bacterial treatment....Pages 181-199
Back Matter....Pages 201-206
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