Ebook: Hypoxia: Into the Next Millennium

Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.

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Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.

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Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.
Content:
Front Matter....Pages i-xvi
Herb Hultgren in Peru: What Causes High Altitude Pulmonary Edema?....Pages 1-22
High Altitude Cerebral Edema and Acute Mountain Sickness....Pages 23-45
Lung Disease at High Altitude....Pages 47-56
Commuting to High Altitude....Pages 57-64
The Pregnant Altitude Visitor....Pages 65-77
High Altitude Pulmonary Edema....Pages 79-79
Pulmonary Hemodynamics: Implications for High Altitude Pulmonary Edema (HAPE)....Pages 81-91
High-Altitude Pulmonary Edema: From Exaggerated Pulmonary Hypertension to a Defect in Transepithelial Sodium Transport....Pages 93-107
Frontiers in Neuroscience....Pages 109-110
What is the Blood-Brain Barrier? A Molecular Perspective....Pages 111-122
Mediators of Cerebral Edema....Pages 123-141
The Hypoxic Brain....Pages 143-143
High Altitude Headache....Pages 145-153
The Hypoxic Brain....Pages 155-169
Food for Thought: Altitude versus Normal Brain Function....Pages 171-183
Are Arterial, Muscle and Working Limb Lactate Exchange Data Obtained on Men at Altitude Consistent with the Hypothesis of an Intracellular Lactate Shuttle?....Pages 185-204
Role of Pyruvate Dehydrogenase in Lactate Production in Exercising Human Skeletal Muscle....Pages 205-218
Cross-Species Studies of Glycolytic Function....Pages 219-229
Hypoxia Induces Cell-Specific Changes in Gene Expression in Vascular Wall Cells: Implications for Pulmonary Hypertension....Pages 231-258
Oxygen and Placental Vascular Development....Pages 259-275
Vascular Growth in Hypoxic Skeletal Muscle....Pages 277-286
Recent Advances in Human Physiology at Extreme Altitude....Pages 287-296
Operation Everest III (COMEX ‘97)....Pages 297-317
Dynamic Cerebral Autoregulation at High Altitude....Pages 319-322
Kangchenjunga 1998....Pages 323-334
Why Does the Exercise Cardiac Output Fall During Altitude Residence and Is It Important?....Pages 335-350
International Consensus Group on Chronic Mountain Sickness....Pages 351-353
A Tribute to Niels Lassen....Pages 355-358
Abstracts from the 11th International Hypoxia Symposium....Pages 359-444
Back Matter....Pages 445-456

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Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.
Content:
Front Matter....Pages i-xvi
Herb Hultgren in Peru: What Causes High Altitude Pulmonary Edema?....Pages 1-22
High Altitude Cerebral Edema and Acute Mountain Sickness....Pages 23-45
Lung Disease at High Altitude....Pages 47-56
Commuting to High Altitude....Pages 57-64
The Pregnant Altitude Visitor....Pages 65-77
High Altitude Pulmonary Edema....Pages 79-79
Pulmonary Hemodynamics: Implications for High Altitude Pulmonary Edema (HAPE)....Pages 81-91
High-Altitude Pulmonary Edema: From Exaggerated Pulmonary Hypertension to a Defect in Transepithelial Sodium Transport....Pages 93-107
Frontiers in Neuroscience....Pages 109-110
What is the Blood-Brain Barrier? A Molecular Perspective....Pages 111-122
Mediators of Cerebral Edema....Pages 123-141
The Hypoxic Brain....Pages 143-143
High Altitude Headache....Pages 145-153
The Hypoxic Brain....Pages 155-169
Food for Thought: Altitude versus Normal Brain Function....Pages 171-183
Are Arterial, Muscle and Working Limb Lactate Exchange Data Obtained on Men at Altitude Consistent with the Hypothesis of an Intracellular Lactate Shuttle?....Pages 185-204
Role of Pyruvate Dehydrogenase in Lactate Production in Exercising Human Skeletal Muscle....Pages 205-218
Cross-Species Studies of Glycolytic Function....Pages 219-229
Hypoxia Induces Cell-Specific Changes in Gene Expression in Vascular Wall Cells: Implications for Pulmonary Hypertension....Pages 231-258
Oxygen and Placental Vascular Development....Pages 259-275
Vascular Growth in Hypoxic Skeletal Muscle....Pages 277-286
Recent Advances in Human Physiology at Extreme Altitude....Pages 287-296
Operation Everest III (COMEX ‘97)....Pages 297-317
Dynamic Cerebral Autoregulation at High Altitude....Pages 319-322
Kangchenjunga 1998....Pages 323-334
Why Does the Exercise Cardiac Output Fall During Altitude Residence and Is It Important?....Pages 335-350
International Consensus Group on Chronic Mountain Sickness....Pages 351-353
A Tribute to Niels Lassen....Pages 355-358
Abstracts from the 11th International Hypoxia Symposium....Pages 359-444
Back Matter....Pages 445-456
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