Ebook: Oxygen Transport to Tissue XVIII

The 23rd annual meeting of the International Society on Oxygen Transport to Tissue took place from August 23-27, 1995, at the Station Square Sheraton along the shores of the Monongahela River where it meets with the Allegheny and Ohio Rivers to form the "Point" of the city of Pittsburgh. Pittsburgh was a convenient location for the meeting be­ ing between both the East and West coasts of the United States and between the Asian and European continents. It is easily accessible by air via its large international airport. In ad­ dition, Pittsburgh has just recently undergone a transition from the steel mills and indus­ tries of old to an age of computers and biotechnology as evidenced by the new Biotechnology Center of the University of Pittsburgh where a lunch and tour were pro­ vided for interested participants. On the tour, the participants got to see the mix of projects ranging from molecular biology to clinical projects studying membrane oxygenators, ven­ tricular assist devices, oxygen carriers, and more, representing the forefront of research on oxygen delivery systems to tissue.

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Assessment of Dysoxia. Calcium-Dependent 02 Sensitivity of Cat Carotid Body; D.G. Buerk, et al.Myocardial Hypoxia-Ischemia. Coronary Flow Response After Myocardial Ischemia May Predict Level of Functional Recovery; R.J.F. Houston, et al.Tissue Oxygen Distribution. The S Factor - A New Derived Hemodynamic Oxygenation Parameter - A Useful Tool for Simplified Mathematical Modeling of Global Problems of Oxygen Transport; K. Farrell, T. Wasser.TissueOxygenation in Tumors. Can NMR Diffusion-Weighted Imaging Provide Quantitative Information on Tumor Interstitial pO2? J.F. Dun, et al.Oxygen Supply-Demand. Peripheral Perfusion & Tissue Oxygenation Improvement Induced By Antihypertensive Medication Combined with Lipoidoproteinosis Treatment; G. Cicco, et al.Angiogenesis &Microcirculation. Modification of Low Density Lipoproteins by Erythrocytes and Hemoglobin Under Hypoxic Conditions; C.Balagopalakrishna, et al.Oxygen Carriers. Anticoagulants & TissueOxygenation. Near Infrared Spectroscopy. Nitric Oxide & Free Radicals.Measurement of Tissue Oxygen. 68 Additional Articles. Index.

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Assessment of Dysoxia. Calcium-Dependent 02 Sensitivity of Cat Carotid Body; D.G. Buerk, et al.Myocardial Hypoxia-Ischemia. Coronary Flow Response After Myocardial Ischemia May Predict Level of Functional Recovery; R.J.F. Houston, et al.Tissue Oxygen Distribution. The S Factor - A New Derived Hemodynamic Oxygenation Parameter - A Useful Tool for Simplified Mathematical Modeling of Global Problems of Oxygen Transport; K. Farrell, T. Wasser.TissueOxygenation in Tumors. Can NMR Diffusion-Weighted Imaging Provide Quantitative Information on Tumor Interstitial pO2? J.F. Dun, et al.Oxygen Supply-Demand. Peripheral Perfusion & Tissue Oxygenation Improvement Induced By Antihypertensive Medication Combined with Lipoidoproteinosis Treatment; G. Cicco, et al.Angiogenesis &Microcirculation. Modification of Low Density Lipoproteins by Erythrocytes and Hemoglobin Under Hypoxic Conditions; C.Balagopalakrishna, et al.Oxygen Carriers. Anticoagulants & TissueOxygenation. Near Infrared Spectroscopy. Nitric Oxide & Free Radicals.Measurement of Tissue Oxygen. 68 Additional Articles. Index.
Content:
Front Matter....Pages i-xv
Calcium-Dependent O2 Sensitivity of Cat Carotid Body....Pages 1-5
Perfusion MRI Assessment of Cerebral Blood Flow and CO2 Reactivity after Controlled Cortical Impact in Rats....Pages 7-12
Histological Assessment of Rodent CNS Tissues to EPR Oximetry Probe Material....Pages 13-21
Regional Differences in Metabolism and Intracellular pH in Response to Moderate Hypoxia....Pages 23-31
Effect of Anesthesia on Cerebral Tissue Oxygen and Cardiopulmonary Parameters in Rats....Pages 33-39
Determination of the PCO2-Dependent Component of the H+ Concentration in Venous and Arterial Blood Plasma....Pages 41-53
Activation of Tyrosine Hydroxylase in Striatum of Newborn Piglets in Response to Hypocapnic Ischemia and Recovery....Pages 55-64
Metabolic Mechanisms of Anoxia Tolerance in the Turtle Brain....Pages 65-73
Age-Related Changes in Brain Metabolism and Vulnerability to Anoxia....Pages 75-81
[Base Excess] vs [Strong ION Difference]....Pages 83-89
[Base Excess] And [Strong ION Difference] During O2-CO2 Exchange....Pages 91-95
Response of Cortical Oxygen and Striatal Extracellular Dopamine to Metabolic Acidosis in Newborn Piglets....Pages 97-102
Clinical Value of Transcutaneous PO2 Assessment During Hyperbaric Oxygen Therapy....Pages 103-112
Coronary Flow Response After Myocardial Ischemia May Predict Level of Functional Recovery....Pages 113-120
Myocardial Adaptation to Acute Oxygen Shortage....Pages 121-127
A Method to Determine Red Blood Cell Spacing in Capillaries of Rat Heart....Pages 129-134
Oxygen Transport to Ischemic Cardiac Myocytes....Pages 135-143
The S Factor—A New Derived Hemodynamic Oxygenation Parameter—A Useful Tool for Simplified Mathematical Modeling of Global Problems of Oxygen Transport....Pages 145-148
Evaluation of Myoglobin Function in the Presence of Axial Diffusion....Pages 149-155
Myocardial Oxygen Tension and Capillary Density in the Isolated Perfused Rat Heart During Pharmacological Intervention....Pages 157-169
Influence of Isokinetic and Ergometric Exercises on Oxygen Partial Pressure Measurement in the Human Knee Joint....Pages 171-181
The Equivalent Krogh Cylinder and Axial Oxygen Transport....Pages 183-189
Influence of O2-Hb Kinetics and the Fahraeus Effect on the Arteriolar Role in Gas Exchange....Pages 191-202
Can NMR Diffusion-Weighted Imaging Provide Quantitative Information on Tumor Interstital pO2?....Pages 203-207
Evaluation of the Concept of “Hypoxic Fraction” as a Descriptor of Tumor Oxygenation Status....Pages 209-214
Optical Imaging of Breast Tumor by Means of Continuous Waves....Pages 215-225
Potential for EPR Oximetry to Guide Treatment Planning for Tumors....Pages 227-232
Vascularization, Blood Flow, Oxygenation, Tissue pH, and Bioenergetic Status of Human Breast Cancer....Pages 233-242
Oxygen Tensions in Rodent Tumors after Irradiation with Neutrons....Pages 243-254
Peripheral Perfusion and Tissue Oxygenation Improvement Induced by Antihypertensive Medication Combined with Lipoidoproteinosis Treatment....Pages 255-260
PO2-Dependent Glomerular Ultrafiltration of Middle-Weight Protein is Modified by Protective Amino Acids....Pages 261-266
Fixed Acid Uptake by Visceral Organs During Early Endotoxemia....Pages 267-274
Release of Lactate by the Lung in Acute Lung Injury....Pages 275-279
Endothelial and Sympathetic Regulation of Vascular Tone in Canine Skeletal Muscle....Pages 281-285
Colloidal Gold Particles as a Marker of Plasma Perfusion and Endocytosis in Kidney, Liver, and Spleen....Pages 287-293
Mathematical Modelling of Local Regulation of Blood Flow by Veno-Arterial Diffusion of Vasoactive Metabolites....Pages 295-301
Regional Cerebral Blood Flow after Subarachnoid Hemorrhage (SAH) in the RAT....Pages 303-311
Effect of Hypoxic Hypoxia on Transmural Gut and Subcutaneous Tissue Oxygen Tension....Pages 313-318
Effects of Hemodilution and Oxygen Breathing on Gut Oxygenation in Anesthetized Dogs....Pages 319-322
Equal Oxygen Delivery May Not Result in Equal Oxygen Consumption....Pages 323-329
Modification of Low Density Lipoproteins by Erythrocytes and Hemoglobin Under Hypoxic Conditions....Pages 331-336
Weak Spots Inside the Myocardium of a Langendorff Rat Heart Observed by Nadh Videofluorometry....Pages 337-345
Microvascular Growth in the Chicken Chorio-allantoic Membrane....Pages 347-351
Different Enzyme Activities in Coronary Capillary Endothelial Cells....Pages 353-358
Myocyte Hypertrophy and Capillarization in Spontaneously Hypertensive Stroke-Prone Rats....Pages 359-364
Adequacy of Cerebral Vascular Remodeling Following Three Weeks of Hypobaric Hypoxia....Pages 365-368
Use of a PFC-Based Oxygen Carrier to Lower the Transfusion Trigger in a Canine Model of Hemodilution and Surgical Blood Loss....Pages 369-376
Effect of Perfluorochemical Emulsion on Hemorheology and Shear Induced Blood Trauma....Pages 377-381
Longitudinal Studies on the Interaction of Perfluorochemicals with Liver Cytochromes P-450 by Means of Testing the Rate of Detoxification of Pentobarbital....Pages 383-390
High Oxygen Partial Pressure in Tissue Delivered by Stabilized Microbubbles....Pages 391-394
Effects of Perflubron Emulsion and 100% Oxygen Breathing on Local Tissue PO2 in Brain Cortex of Unanaesthetized Rabbits....Pages 395-401
Chromatographic Process Identification for Protein C Purification Using Frequency Response Analysis....Pages 403-409
Separation of Recombinant Human Protein C from Transgenic Animal Milk Using Immobilized Metal Affinity Chromatography....Pages 411-418
Pulmonary Delivery of Human Protein C and Factor IX....Pages 419-428
Reusable, Real-Time, Immuno-Optical Protein C Biosensor....Pages 429-435
Effect of Exercise and Ischemia on Tissue Oximetry and Cytochrome in Normal Subjects, Patients with Chronic Limb Pain, and Patients with Mitochondrial Mitopathies....Pages 437-444
Measurement of Cerebral Venous Saturation in Adults using Near Infrared Spectroscopy....Pages 445-451
Simultaneous Assessment of Cerebral Oxygenation and Hemodynamics During a Motor Task....Pages 453-460
Length of Resting Period Between Stimulation Cycles Modulates Hemodynamic Response to a Motor Stimulus....Pages 461-469
Applications of NIRS for Measurements of Tissue Oxygenation and Haemodynamics During Surgery....Pages 471-480
How to Evaluate Slow Oxygenation Changes to Estimate Absolute Cerebral Haemoglobin Concentration by Near Infrared Spectrophotometry in Neonates....Pages 481-493
Effect of Antioxidants on Hyperoxia-Induced ICAM-1 Expression in Human Endothelial Cells....Pages 495-501
Nitric Oxide Inhibits Growth of Vascular Smooth Muscle Cells In Vitro by Mechanisms Independent of Guanylate Cyclase....Pages 503-511
Effects of Puncturing on the Measurement of Local Oxygen Pressure Using Polarographic Microelectrodes....Pages 513-518
Comparisons of Measurements of pO2 in Tissue In Vivo by EPR Oximetry and Micro-Electrodes....Pages 519-525
Catchment Depths of Surface Electrodes for H2 and O2 in Tissue....Pages 527-541
Intrarenal pO2 Measured by EPR Oximetry and the Effects of Bacterial Endotoxin....Pages 543-549
Measurements of Oxygen Tension in the Rat Kidney After Contrast Media Using an Oxygen Microelectrode with a Guard Cathode....Pages 551-556
Oxygen Distribution in the Vasculature of Mouse Tissue In Vivo Measured Using a Near Infra Red Phosphor....Pages 557-568
Imaging of Oxygen Distribution in the Surface and Deep Areas of the Kidney....Pages 569-576
Extended Porphyrins....Pages 577-583
Back Matter....Pages 585-590
....Pages 591-595