Ebook: Genomic Instability and Immortality in Cancer

Telomeres and Cell Division in Drosophila melanogaster; G. Cenci, M.Gatti. A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors; J.W. Gray et al. Cell Cycle Control of Genetic Stability; G.M. Wahi et al. Aneupioidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression; W. Ciaretti. p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and Its Role in Cell Cycle Control; M.L. Agarwal et al. Recombining DNA Damage Repair, Basal Transcription and Human Syndromes; J.H.J. Hoeijmakers etal. Telomere Length Regulation by the Pifl DNA Helicase; E.K. Monsonet al. Consequences of Mutations that Alter Telomeres in the Yeast K .lactis; J. McEachern, E.H. Blackburn. Regulation of Telomere Length in Mammalian Cells; B.R. Grimes et al. The DNA Damage Checkpoint; L.Hartwell et al. A Eukaryotic Cell Cycle; K. Nasmyth. The Integration of Signaling Pathways in Mammalian Cells; G.I. Evan et al. Antitumor Drugs and Yeast Cell Cycle Checkpoints; M. Weinberger et al. Mechanisms of Neoplastic Progression in Barrett's Esophagus; M.T.Barrett et al. E2F-1 Degradation by the Ubiquitin Proteasome Pathway; F. Hofmann, D. Livingston. 2 Additional Articles. Index.

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Telomeres and Cell Division in Drosophila melanogaster; G. Cenci, M.Gatti. A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors; J.W. Gray et al. Cell Cycle Control of Genetic Stability; G.M. Wahi et al. Aneupioidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression; W. Ciaretti. p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and Its Role in Cell Cycle Control; M.L. Agarwal et al. Recombining DNA Damage Repair, Basal Transcription and Human Syndromes; J.H.J. Hoeijmakers etal. Telomere Length Regulation by the Pifl DNA Helicase; E.K. Monsonet al. Consequences of Mutations that Alter Telomeres in the Yeast K .lactis; J. McEachern, E.H. Blackburn. Regulation of Telomere Length in Mammalian Cells; B.R. Grimes et al. The DNA Damage Checkpoint; L.Hartwell et al. A Eukaryotic Cell Cycle; K. Nasmyth. The Integration of Signaling Pathways in Mammalian Cells; G.I. Evan et al. Antitumor Drugs and Yeast Cell Cycle Checkpoints; M. Weinberger et al. Mechanisms of Neoplastic Progression in Barrett's Esophagus; M.T.Barrett et al. E2F-1 Degradation by the Ubiquitin Proteasome Pathway; F. Hofmann, D. Livingston. 2 Additional Articles. Index.
Content:
Front Matter....Pages i-x
Telomeres and Cell Division in Drosophila melanogaster ....Pages 1-12
A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors....Pages 13-31
Cell Cycle Control of Genetic Stability....Pages 33-52
Aneuploidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression....Pages 53-68
p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and its Role in Cell Cycle Control....Pages 69-81
Recombining DNA Damage Repair, Basal Transcription, and Human Syndromes....Pages 83-96
Telomere Length Regulation by the Pif1 DNA Helicase....Pages 97-110
Consequences of Mutations that Alter Telomeres in the Yeast K. lactis ....Pages 111-131
Regulation of Telomere Length in Mammalian Cells....Pages 133-147
The DNA Damage Checkpoint....Pages 149-157
A Eukaryotic Cell Cycle....Pages 159-169
The Integration of Signalling Pathways in Mammalian Cells....Pages 171-187
Antitumor Drugs and Yeast Cell Cycle Checkpoints....Pages 189-194
Neoplastic Progression in Barrett’s Esophagus....Pages 195-214
E2F-1 Degradation by the Ubiquitin-Proteasome Pathway....Pages 215-227
Cdk4-Cyclin D1 and Cdk2-Cyclin E/A Phosphorylate Different Sites in the RB Protein....Pages 229-231
Cell Cycle Regulatory Proteins as Targets of Oncogenic Events....Pages 233-245
Back Matter....Pages 247-251

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Telomeres and Cell Division in Drosophila melanogaster; G. Cenci, M.Gatti. A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors; J.W. Gray et al. Cell Cycle Control of Genetic Stability; G.M. Wahi et al. Aneupioidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression; W. Ciaretti. p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and Its Role in Cell Cycle Control; M.L. Agarwal et al. Recombining DNA Damage Repair, Basal Transcription and Human Syndromes; J.H.J. Hoeijmakers etal. Telomere Length Regulation by the Pifl DNA Helicase; E.K. Monsonet al. Consequences of Mutations that Alter Telomeres in the Yeast K .lactis; J. McEachern, E.H. Blackburn. Regulation of Telomere Length in Mammalian Cells; B.R. Grimes et al. The DNA Damage Checkpoint; L.Hartwell et al. A Eukaryotic Cell Cycle; K. Nasmyth. The Integration of Signaling Pathways in Mammalian Cells; G.I. Evan et al. Antitumor Drugs and Yeast Cell Cycle Checkpoints; M. Weinberger et al. Mechanisms of Neoplastic Progression in Barrett's Esophagus; M.T.Barrett et al. E2F-1 Degradation by the Ubiquitin Proteasome Pathway; F. Hofmann, D. Livingston. 2 Additional Articles. Index.
Content:
Front Matter....Pages i-x
Telomeres and Cell Division in Drosophila melanogaster ....Pages 1-12
A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors....Pages 13-31
Cell Cycle Control of Genetic Stability....Pages 33-52
Aneuploidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression....Pages 53-68
p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and its Role in Cell Cycle Control....Pages 69-81
Recombining DNA Damage Repair, Basal Transcription, and Human Syndromes....Pages 83-96
Telomere Length Regulation by the Pif1 DNA Helicase....Pages 97-110
Consequences of Mutations that Alter Telomeres in the Yeast K. lactis ....Pages 111-131
Regulation of Telomere Length in Mammalian Cells....Pages 133-147
The DNA Damage Checkpoint....Pages 149-157
A Eukaryotic Cell Cycle....Pages 159-169
The Integration of Signalling Pathways in Mammalian Cells....Pages 171-187
Antitumor Drugs and Yeast Cell Cycle Checkpoints....Pages 189-194
Neoplastic Progression in Barrett’s Esophagus....Pages 195-214
E2F-1 Degradation by the Ubiquitin-Proteasome Pathway....Pages 215-227
Cdk4-Cyclin D1 and Cdk2-Cyclin E/A Phosphorylate Different Sites in the RB Protein....Pages 229-231
Cell Cycle Regulatory Proteins as Targets of Oncogenic Events....Pages 233-245
Back Matter....Pages 247-251
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