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This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Healthand Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.


This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Healthand Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.
Content:
Front Matter....Pages i-2
Front Matter....Pages 3-3
Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat....Pages 5-11
Effect of short-term treatment with a monoclonal antibody to P-selectin on balloon catheter-induced: Intimal hyperplasia, re-endothelialization, and attenuation of endothelial-dependent relaxation....Pages 13-20
Differential regulation of G-protein expression by vasoactive peptides....Pages 21-27
Endothelin contraction in pig coronary artery: Receptor types and Ca2+-mobilization....Pages 29-33
Activation of the neutrophil and loss of plasma glutathione during Mg-deficiency — modulation by nitric oxide synthase inhibition....Pages 35-39
Velocity of translation of single actin filaments (AF) by myosin heads from antigen-sensitized airway smooth muscle....Pages 41-46
Smooth muscle contractility and protein tyrosine phosphorylation....Pages 47-51
Coronary artery smooth muscle in culture: Migration of heterogeneous cell populations from vessel wall....Pages 53-59
An overview of the influence of ACE inhibitors on fetal-placental circulation and perinatal development....Pages 61-71
Front Matter....Pages 73-73
Differential nature of cross-talk among three G-coupled receptors regulating adenylyl cyclase in rat cardiomyocytes chronically exposed to receptor agonists....Pages 75-82
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle....Pages 83-88
Expression of fibroblast growth factor receptor-1 in rat heart H9c2 myoblasts increases cell proliferation....Pages 89-97
Identification of an HMG-like protein involved in regulation of Na+/H+ exchanger expression....Pages 99-106
Cytochemical and immunocytochemical localization of Na,K-ATPase ? subunit isoenzymes in the rat heart....Pages 107-112
Estradiol modulates the sodium pump in the heart sarcolemma....Pages 113-118
Thyroid hormones differentially affect sarcoplasmic reticulum function in rat atria and ventricles....Pages 119-126
Dietary and physiological studies to investigate the relationship between calcium and magnesium signalling in the mammalian myocardium....Pages 127-134
Biological significance of phosphorylation and myristoylation in the regulation of cardiac muscle proteins....Pages 135-143
Contributions of increased efficiency and capacity of protein synthesis to rapid cardiac growth....Pages 145-151
Cell-cycle dependent anti-FGF-2 staining of chicken cardiac myocytes: Movement from chromosomal to cleavage furrow- and midbody-associated sites....Pages 153-161
Front Matter....Pages 73-73
An endogenous positive inotropic factor (EPIF) from porcine heart: Its effects on sarcoplasmic reticular (SR) Ca2+ metabolism....Pages 163-168
Front Matter....Pages 169-169
Prostaglandins attenuate cardiac contractile dysfunction produced by free radical generation but not by hydrogen peroxide....Pages 171-178
Changes in fatty acid compositions of myocardial lipids in rats with heart failure following myocardial infarction....Pages 179-189
Mechanisms that may be involved in calcium tolerance of the diabetic heart....Pages 191-198
Increases of T-type Ca2+ current in heart cells of the cardiomyopathic hamster....Pages 199-204
Myocardial functional preservation during ischemia: Influence of beta blocking agents....Pages 205-210
Phosphorylation by protein kinase C and the responsiveness of Mg2+-ATPase to Ca2+ of myofibrils isolated from stunned and non-stunned porcine myocardium....Pages 211-218
Is there a link between impaired glucose metabolism and protein kinase C activity in the diabetic heart?....Pages 219-225
A new technique of coronary artery ligation: Experimental myocardial infarction in rats in vivo with reduced mortality....Pages 227-233
Adriamycin depresses in vivo and in vitro phos-phatidylethanolamine N-Methylation in rat heart sarcolemma....Pages 235-240
A calcium stimulated cysteine protease involved in isoproterenol induced cardiac hypertrophy....Pages 241-248
Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster....Pages 249-256
Na+-H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemia reperfusion; 31P NMR studies....Pages 257-264
Increased gene expression of plasminogen activators and inhibitors in left ventricular hypertrophy....Pages 265-271
Cardiac hypertrophy: Old concepts, new perspectives....Pages 273-279
Characteristics of the myocardial PM-FABP: Effect of diabetes mellitus....Pages 281-286
Cardiomyopathies and mitochondrial DNA mutations....Pages 287-290
Cardiac depression and cellular injury in hemorrhagic shock and reinfusion: Role of free radicals....Pages 291-301
Ischemic preconditioning is not additive to preservation with hypothermia or crystalloid cardioplegia in the globally ischemic rat heart....Pages 303-313
Front Matter....Pages 315-315
Regulation of Ca2+ homeostasis by glucose metabolism in rat brain....Pages 317-326
Front Matter....Pages 315-315
Age- and sex-related differences in nuclear lipid content and nucleoside triphosphatase activity in the JCR:LA-cp corpulent rat....Pages 327-335
Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion....Pages 337-347
Back Matter....Pages 349-353


This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Healthand Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.
Content:
Front Matter....Pages i-2
Front Matter....Pages 3-3
Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat....Pages 5-11
Effect of short-term treatment with a monoclonal antibody to P-selectin on balloon catheter-induced: Intimal hyperplasia, re-endothelialization, and attenuation of endothelial-dependent relaxation....Pages 13-20
Differential regulation of G-protein expression by vasoactive peptides....Pages 21-27
Endothelin contraction in pig coronary artery: Receptor types and Ca2+-mobilization....Pages 29-33
Activation of the neutrophil and loss of plasma glutathione during Mg-deficiency — modulation by nitric oxide synthase inhibition....Pages 35-39
Velocity of translation of single actin filaments (AF) by myosin heads from antigen-sensitized airway smooth muscle....Pages 41-46
Smooth muscle contractility and protein tyrosine phosphorylation....Pages 47-51
Coronary artery smooth muscle in culture: Migration of heterogeneous cell populations from vessel wall....Pages 53-59
An overview of the influence of ACE inhibitors on fetal-placental circulation and perinatal development....Pages 61-71
Front Matter....Pages 73-73
Differential nature of cross-talk among three G-coupled receptors regulating adenylyl cyclase in rat cardiomyocytes chronically exposed to receptor agonists....Pages 75-82
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle....Pages 83-88
Expression of fibroblast growth factor receptor-1 in rat heart H9c2 myoblasts increases cell proliferation....Pages 89-97
Identification of an HMG-like protein involved in regulation of Na+/H+ exchanger expression....Pages 99-106
Cytochemical and immunocytochemical localization of Na,K-ATPase ? subunit isoenzymes in the rat heart....Pages 107-112
Estradiol modulates the sodium pump in the heart sarcolemma....Pages 113-118
Thyroid hormones differentially affect sarcoplasmic reticulum function in rat atria and ventricles....Pages 119-126
Dietary and physiological studies to investigate the relationship between calcium and magnesium signalling in the mammalian myocardium....Pages 127-134
Biological significance of phosphorylation and myristoylation in the regulation of cardiac muscle proteins....Pages 135-143
Contributions of increased efficiency and capacity of protein synthesis to rapid cardiac growth....Pages 145-151
Cell-cycle dependent anti-FGF-2 staining of chicken cardiac myocytes: Movement from chromosomal to cleavage furrow- and midbody-associated sites....Pages 153-161
Front Matter....Pages 73-73
An endogenous positive inotropic factor (EPIF) from porcine heart: Its effects on sarcoplasmic reticular (SR) Ca2+ metabolism....Pages 163-168
Front Matter....Pages 169-169
Prostaglandins attenuate cardiac contractile dysfunction produced by free radical generation but not by hydrogen peroxide....Pages 171-178
Changes in fatty acid compositions of myocardial lipids in rats with heart failure following myocardial infarction....Pages 179-189
Mechanisms that may be involved in calcium tolerance of the diabetic heart....Pages 191-198
Increases of T-type Ca2+ current in heart cells of the cardiomyopathic hamster....Pages 199-204
Myocardial functional preservation during ischemia: Influence of beta blocking agents....Pages 205-210
Phosphorylation by protein kinase C and the responsiveness of Mg2+-ATPase to Ca2+ of myofibrils isolated from stunned and non-stunned porcine myocardium....Pages 211-218
Is there a link between impaired glucose metabolism and protein kinase C activity in the diabetic heart?....Pages 219-225
A new technique of coronary artery ligation: Experimental myocardial infarction in rats in vivo with reduced mortality....Pages 227-233
Adriamycin depresses in vivo and in vitro phos-phatidylethanolamine N-Methylation in rat heart sarcolemma....Pages 235-240
A calcium stimulated cysteine protease involved in isoproterenol induced cardiac hypertrophy....Pages 241-248
Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster....Pages 249-256
Na+-H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemia reperfusion; 31P NMR studies....Pages 257-264
Increased gene expression of plasminogen activators and inhibitors in left ventricular hypertrophy....Pages 265-271
Cardiac hypertrophy: Old concepts, new perspectives....Pages 273-279
Characteristics of the myocardial PM-FABP: Effect of diabetes mellitus....Pages 281-286
Cardiomyopathies and mitochondrial DNA mutations....Pages 287-290
Cardiac depression and cellular injury in hemorrhagic shock and reinfusion: Role of free radicals....Pages 291-301
Ischemic preconditioning is not additive to preservation with hypothermia or crystalloid cardioplegia in the globally ischemic rat heart....Pages 303-313
Front Matter....Pages 315-315
Regulation of Ca2+ homeostasis by glucose metabolism in rat brain....Pages 317-326
Front Matter....Pages 315-315
Age- and sex-related differences in nuclear lipid content and nucleoside triphosphatase activity in the JCR:LA-cp corpulent rat....Pages 327-335
Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion....Pages 337-347
Back Matter....Pages 349-353
....
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