Ebook: G Protein-Coupled Receptors

This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins). Molecular cloning of members of the G protein-coupled receptor superfamily has complemented pharmacological investigations in providing a realization of the structural and functional diversity of these receptors. An increased understanding of the involvement of particular receptor subtypes in normal and pathophysiological processes represents exciting possibilities for the development of highly specific and effective therapeutic agents.

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Content:
Front Matter....Pages i-xiii
Cell Surface Receptors and the G Protein-Coupled Receptor Superfamily....Pages 1-63
Signaling Through G Protein-Coupled Receptors....Pages 65-93
Structural Determinants of Receptor Function....Pages 95-133
G Protein-Coupled Receptors, Pathology and Therapeutic Strategies....Pages 135-169
Future Prospects....Pages 171-175
Back Matter....Pages 177-183

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Content:
Front Matter....Pages i-xiii
Cell Surface Receptors and the G Protein-Coupled Receptor Superfamily....Pages 1-63
Signaling Through G Protein-Coupled Receptors....Pages 65-93
Structural Determinants of Receptor Function....Pages 95-133
G Protein-Coupled Receptors, Pathology and Therapeutic Strategies....Pages 135-169
Future Prospects....Pages 171-175
Back Matter....Pages 177-183
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