Ebook: Apoptosis in Hormone-Dependent Cancers

It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy. Experts in this area report on the regulation and control of apoptosis in hormone dependent (neoplastic) tissue and the possibility to exploit active cell death for therapeutic application.

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Content:
Front Matter....Pages I-XIV
Hormonal Control of Prostatic Differentiation and Morphogenesis: The Impact of Apoptosis and Steroid Hormone Receptor Expression....Pages 1-33
Apoptosis in Experimental Prostate Cancer....Pages 35-55
Therapeutic Significance of Apoptosis in the Treatment of Androgen-Dependent and Androgen-Independent Prostate Cancer....Pages 57-69
Apoptosis in Relation to Androgen Independence in Experimental and Clinical Prostate Cancer....Pages 71-82
Active Cell Death and Cancer....Pages 83-101
Modulation of Apoptosis by Oncogenes....Pages 103-122
Tenascin and Extracellular Matrix: Possible Biological Implications During Regression and Carcinogenesis of the Prostate....Pages 123-142
Anti-Growth Factor Activity of Antiestrogens in Human Breast Cancer Cells: A Review....Pages 143-160
Differentiation and Apoptosis as a Therapeutic Strategy for Hormone-Dependent Cancers....Pages 161-180
1,25 Dihydroxyvitamin D3: Coordinate Regulator of Active Cell Death and Proliferation in MCF-7 Breast Cancer Cells....Pages 181-200
Vitamin D3 Derivatives and Breast Cancer....Pages 201-224
The Role of Growth Factors and Extracellular Matrix Proteases in Active Cell Death in the Prostate....Pages 225-246
Back Matter....Pages 247-250

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Content:
Front Matter....Pages I-XIV
Hormonal Control of Prostatic Differentiation and Morphogenesis: The Impact of Apoptosis and Steroid Hormone Receptor Expression....Pages 1-33
Apoptosis in Experimental Prostate Cancer....Pages 35-55
Therapeutic Significance of Apoptosis in the Treatment of Androgen-Dependent and Androgen-Independent Prostate Cancer....Pages 57-69
Apoptosis in Relation to Androgen Independence in Experimental and Clinical Prostate Cancer....Pages 71-82
Active Cell Death and Cancer....Pages 83-101
Modulation of Apoptosis by Oncogenes....Pages 103-122
Tenascin and Extracellular Matrix: Possible Biological Implications During Regression and Carcinogenesis of the Prostate....Pages 123-142
Anti-Growth Factor Activity of Antiestrogens in Human Breast Cancer Cells: A Review....Pages 143-160
Differentiation and Apoptosis as a Therapeutic Strategy for Hormone-Dependent Cancers....Pages 161-180
1,25 Dihydroxyvitamin D3: Coordinate Regulator of Active Cell Death and Proliferation in MCF-7 Breast Cancer Cells....Pages 181-200
Vitamin D3 Derivatives and Breast Cancer....Pages 201-224
The Role of Growth Factors and Extracellular Matrix Proteases in Active Cell Death in the Prostate....Pages 225-246
Back Matter....Pages 247-250
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