Ebook: Advances in Nutrition and Cancer

This volume contains the scientific contributions presented at the International Symposium held in Naples, Italy, in November 1992 at the National Tumor Institute "Fondazione Pascale". The Meeting gathered together experts from different disciplines, all involved in the vital and timely subject of Nutrition and Cancer. About 15 years ago a consensus among cancer epidemiologists began to emerge suggesting that diet might be responsible for 30-60% of the cancers in the developed world. The best estimate, reported in a now classical paper by Richard Doll and Richard Peto (1981), was that by dietary modification, it would be possible to reduce fatal cancers by about 35%. Within about six years there was widespread agreement that the principal changes required were a reduction in consumption of fat, along with an increase in the consumption of fruit, green and yellow vegetables, dietary fiber, and some micronutrients. Attention was also paid to the methods of cooking and preservation of foodstuffs. On the other hand very few, if any, effects were attributed to food additives and to pollution of food by trace pesticides, to which the general public often gives unfounded importance.

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Molecular Bases of Malignant Transformation: Growth Factors and Malignant Transformation; S.A. Aaronson, et al. Tumor Suppressor Genes which Encode Transcriptional Repressors; F.J. Rauscher, III Enzyme Deficiency and Tumor Suppressor Genes; F. Della Ragione, et al. HOX Gene Expression in Human Cancers; P. Barba, et al.EpidemiologicalStudies: Risk Factors and Diet: Nutrition and Cancer; F. Fidanza Diet and Precancerous Lesions; M.J. Hill Dietary Prevention of Chronic Diseases; S. Panico, et al. Dietary Fibers and Cancer; A. Giacosa, etal. Dietary Fiber in the Prevention of Cardiovascular Disease; G.Riccardi, A.V. CiardulloClinical Research and Perspectives: Diet and Large Bowel Cancer J. Faivre, et al. On the Nutritional Etiology of Breast Cancer; F. de Waard Diet and Gastric Cancer; P.I. Reed Diet, Coeliac Disease and Gatrointestinal Neoplasm; G. Mazzacca 4 additional articles. Index.

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Molecular Bases of Malignant Transformation: Growth Factors and Malignant Transformation; S.A. Aaronson, et al. Tumor Suppressor Genes which Encode Transcriptional Repressors; F.J. Rauscher, III Enzyme Deficiency and Tumor Suppressor Genes; F. Della Ragione, et al. HOX Gene Expression in Human Cancers; P. Barba, et al.EpidemiologicalStudies: Risk Factors and Diet: Nutrition and Cancer; F. Fidanza Diet and Precancerous Lesions; M.J. Hill Dietary Prevention of Chronic Diseases; S. Panico, et al. Dietary Fibers and Cancer; A. Giacosa, etal. Dietary Fiber in the Prevention of Cardiovascular Disease; G.Riccardi, A.V. CiardulloClinical Research and Perspectives: Diet and Large Bowel Cancer J. Faivre, et al. On the Nutritional Etiology of Breast Cancer; F. de Waard Diet and Gastric Cancer; P.I. Reed Diet, Coeliac Disease and Gatrointestinal Neoplasm; G. Mazzacca 4 additional articles. Index.
Content:
Front Matter....Pages i-4
Front Matter....Pages 5-5
Growth Factors and Malignant Transformation....Pages 7-22
Tumor Suppressor Genes which Encode Transcriptional Repressors: Studies on the EGR and Wilms’ Tumor (WT1) Gene Products....Pages 23-29
Enzyme Deficiency and Tumor Suppressor Genes: Absence of 5’-Deoxy-5’-Methylthioadenosine Phosphorylase in Human Tumors....Pages 31-43
HOX Gene Expression in Human Cancers....Pages 45-57
Thyroid Specific Expression of the Ki-ras Oncogene in Transgenic Mice....Pages 59-62
Front Matter....Pages 63-63
Nutrition and Cancer: General Considerations....Pages 65-67
Diet and Precancerous Lesions....Pages 69-74
Dietary Prevention of Chronic Diseases: The Potential for Cardiovascular Diseases....Pages 75-83
Dietary Fibres and Cancer....Pages 85-97
Dietary Fiber in the Prevention of Cardiovascular Disease....Pages 99-104
Front Matter....Pages 105-105
Diet and Large Bowel Cancer....Pages 107-118
On the Nutritional Etiology of Breast Cancer....Pages 119-122
Diet and Gastric Cancer....Pages 123-132
Diet, Coeliac Disease and Gastrointestinal Neoplasm....Pages 133-136
Protective Aspects of the Mediterranean Diet....Pages 137-144
The Role of “Bioelectrical Impedance Analysis” in the Evaluation of the Nutritional Status of Cancer Patients....Pages 145-148
High Serum HDL-Cholesterol in Pre- and Post-Menopausal Women with Breast Cancer in Southern Italy....Pages 149-153
Back Matter....Pages 155-169

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Molecular Bases of Malignant Transformation: Growth Factors and Malignant Transformation; S.A. Aaronson, et al. Tumor Suppressor Genes which Encode Transcriptional Repressors; F.J. Rauscher, III Enzyme Deficiency and Tumor Suppressor Genes; F. Della Ragione, et al. HOX Gene Expression in Human Cancers; P. Barba, et al.EpidemiologicalStudies: Risk Factors and Diet: Nutrition and Cancer; F. Fidanza Diet and Precancerous Lesions; M.J. Hill Dietary Prevention of Chronic Diseases; S. Panico, et al. Dietary Fibers and Cancer; A. Giacosa, etal. Dietary Fiber in the Prevention of Cardiovascular Disease; G.Riccardi, A.V. CiardulloClinical Research and Perspectives: Diet and Large Bowel Cancer J. Faivre, et al. On the Nutritional Etiology of Breast Cancer; F. de Waard Diet and Gastric Cancer; P.I. Reed Diet, Coeliac Disease and Gatrointestinal Neoplasm; G. Mazzacca 4 additional articles. Index.
Content:
Front Matter....Pages i-4
Front Matter....Pages 5-5
Growth Factors and Malignant Transformation....Pages 7-22
Tumor Suppressor Genes which Encode Transcriptional Repressors: Studies on the EGR and Wilms’ Tumor (WT1) Gene Products....Pages 23-29
Enzyme Deficiency and Tumor Suppressor Genes: Absence of 5’-Deoxy-5’-Methylthioadenosine Phosphorylase in Human Tumors....Pages 31-43
HOX Gene Expression in Human Cancers....Pages 45-57
Thyroid Specific Expression of the Ki-ras Oncogene in Transgenic Mice....Pages 59-62
Front Matter....Pages 63-63
Nutrition and Cancer: General Considerations....Pages 65-67
Diet and Precancerous Lesions....Pages 69-74
Dietary Prevention of Chronic Diseases: The Potential for Cardiovascular Diseases....Pages 75-83
Dietary Fibres and Cancer....Pages 85-97
Dietary Fiber in the Prevention of Cardiovascular Disease....Pages 99-104
Front Matter....Pages 105-105
Diet and Large Bowel Cancer....Pages 107-118
On the Nutritional Etiology of Breast Cancer....Pages 119-122
Diet and Gastric Cancer....Pages 123-132
Diet, Coeliac Disease and Gastrointestinal Neoplasm....Pages 133-136
Protective Aspects of the Mediterranean Diet....Pages 137-144
The Role of “Bioelectrical Impedance Analysis” in the Evaluation of the Nutritional Status of Cancer Patients....Pages 145-148
High Serum HDL-Cholesterol in Pre- and Post-Menopausal Women with Breast Cancer in Southern Italy....Pages 149-153
Back Matter....Pages 155-169
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