Ebook: Endoplasmic Reticulum

In step with the surge of interest in the endoplasmic reticulum, the current volume takes an integrated look at this functionally diverse organelle. Coverage includes protein translocation and export, lipid metabolism, antigen presentation, and many other subjects, gleaned from such diverse fields as cell biology, enzymology and membrane biochemistry, immunology, and signal transduction.

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In step with the surge of interest in the endoplasmic reticulum, the current volume takes an integrated look at this functionally diverse organelle. Coverage includes protein translocation and export, lipid metabolism, antigen presentation, and many other subjects, gleaned from such diverse fields as cell biology, enzymology and membrane biochemistry, immunology, and signal transduction.
Content:
Front Matter....Pages i-xxiii
Mechanisms of Translocation of Proteins across Membranes....Pages 1-15
Components and Mechanisms Involved in Transport of Proteins into the Endoplasmic Reticulum....Pages 17-40
Folding, Assembly, and Posttranslational Modification of Proteins within the Lumen of the Endoplasmic Reticulum....Pages 41-80
Biological Functions and Biosynthesis of Glycolipid-Anchored Membrane Proteins....Pages 81-93
Membrane Cycling between the ER and Golgi Apparatus and Its Role in Biosynthetic Transport....Pages 95-119
The Intermediate Compartment between Endoplasmic Reticulum and Golgi Complex in Mammalian Cells....Pages 121-142
The Endoplasmic Reticulum as a Site of Protein Degradation....Pages 143-168
The Endoplasmic Reticulum Is the Site of Lipoprotein Assembly and Regulation of Secretion....Pages 169-187
Endoplasmic Reticulum and the Control of Ca2+ Homeostasis....Pages 189-207
Antigen Processing and Presentation the Role of the Endoplasmic Reticulum....Pages 209-228
Distribution, Biosynthesis, and Function of Mevalonate Pathway Lipids....Pages 229-272
Phospholipid Translocation in the Endoplasmic Reticulum....Pages 273-285
Cytochrome P-450 in the Endoplasmic Reticulum Biosynthesis, Distribution, Induction, and Degradation....Pages 287-311
NADH-Cytochrome b5 Reductase and Cytochrome b5 the Problem of Posttranslational Targeting to the Endoplasmic Reticulum....Pages 313-341
Motility and Construction of the Endoplasmic Reticulum in Living Cells....Pages 343-352
Back Matter....Pages 353-358

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In step with the surge of interest in the endoplasmic reticulum, the current volume takes an integrated look at this functionally diverse organelle. Coverage includes protein translocation and export, lipid metabolism, antigen presentation, and many other subjects, gleaned from such diverse fields as cell biology, enzymology and membrane biochemistry, immunology, and signal transduction.
Content:
Front Matter....Pages i-xxiii
Mechanisms of Translocation of Proteins across Membranes....Pages 1-15
Components and Mechanisms Involved in Transport of Proteins into the Endoplasmic Reticulum....Pages 17-40
Folding, Assembly, and Posttranslational Modification of Proteins within the Lumen of the Endoplasmic Reticulum....Pages 41-80
Biological Functions and Biosynthesis of Glycolipid-Anchored Membrane Proteins....Pages 81-93
Membrane Cycling between the ER and Golgi Apparatus and Its Role in Biosynthetic Transport....Pages 95-119
The Intermediate Compartment between Endoplasmic Reticulum and Golgi Complex in Mammalian Cells....Pages 121-142
The Endoplasmic Reticulum as a Site of Protein Degradation....Pages 143-168
The Endoplasmic Reticulum Is the Site of Lipoprotein Assembly and Regulation of Secretion....Pages 169-187
Endoplasmic Reticulum and the Control of Ca2+ Homeostasis....Pages 189-207
Antigen Processing and Presentation the Role of the Endoplasmic Reticulum....Pages 209-228
Distribution, Biosynthesis, and Function of Mevalonate Pathway Lipids....Pages 229-272
Phospholipid Translocation in the Endoplasmic Reticulum....Pages 273-285
Cytochrome P-450 in the Endoplasmic Reticulum Biosynthesis, Distribution, Induction, and Degradation....Pages 287-311
NADH-Cytochrome b5 Reductase and Cytochrome b5 the Problem of Posttranslational Targeting to the Endoplasmic Reticulum....Pages 313-341
Motility and Construction of the Endoplasmic Reticulum in Living Cells....Pages 343-352
Back Matter....Pages 353-358
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