Ebook: Uses of Immobilized Biological Compounds

In Uses of Immobilized Biological Compounds the reader will find a comprehensive survey of the field written by acknowledged experts who met in Brixen, Italy, between May 9 and 14, 1993 for a NATO Advanced Research Workshop devoted to the topic. The resulting volume presents a critical review of the latest results in the area and sets guidelines for future research. The 53 reports presented here cover: (A) General Aspects of Immobilizing Biological Compounds; (B) Medical, Clinical and Pharmaceutical Applications; (C) Electrochemical Biosensors; (E) Defense Applications; (F) Immunosensors and Receptors; (G) Food, Environmental, Clinical and Analytical Applications; and (H) Biotechnology and Marketing. In short, all aspects of the area are presented, in a compact format which will appeal to undergraduates, technicians, and professional scientists in the food, clinical, environmental, pharmaceutical and industrial fields.

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Content:
Front Matter....Pages i-xxiii
Immobilization of Biological Species on Bilayer Lipid Membranes....Pages 1-10
Polymeric Environments for Proteins and Whole Cells in Molecular Sensors....Pages 11-21
Use of Red Blood Cells (RBC) as Carriers of Bioactive Compounds....Pages 23-33
Theoretical and Experimental Aspects for Improvement of Electrochemical Biosensors by Various Kinds of Immobilization....Pages 35-45
Development and Characterization of Polymeric Biomaterials for Bioactive Agent Immobilization....Pages 47-56
Two-Dimensional (GLYCO)Protein Crystals as Immobilization Matrix for Functional Molecules....Pages 57-66
Application of Graphite-Epoxy Composites in the Construction of Elctrochemical Sensors and Biosensors....Pages 67-79
Novel Phema Membranes for Potential Bioelectrode use....Pages 81-90
Immobilization of Cell Cycle Specific Drug DFMO for Chemotherapy....Pages 91-99
Use of Immobilized Biological Compounds in Drug Analysis....Pages 101-113
In Vivo Monitoring with Microdialysis Probe....Pages 115-122
Immobilised Catalase and Hydrogen Peroxide — A Novel Contact Lens Disinfection System....Pages 123-130
Ex-Vivo Sensors; Microencapsulation of Enzyme Layer in Biosensors....Pages 131-140
Clinical Application of Biosensing with Amperometric Detection of Ammonia-Nitrogen....Pages 141-150
Therapeutic Potential of Immobilized Enzymes....Pages 151-160
Optimization of Membranes with Glucose Oxidase for Glucose Determination using Oxygen Electrode....Pages 161-170
Multienzyme Biosensors — Coupled Enzyme Reactions and Enzyme Activation....Pages 171-179
Three Different Approaches for Preparing GLOD and GLDH Reactors. Application for the Assay of Glutamates in Real Samples Using a FIA — System....Pages 181-189
Enzyme Immobilization on Chitin and Chitosan for Construction of Enzymatic Sensors....Pages 191-200
Electrochemical Biosensors....Pages 201-210
Novel Approaches to the Development of Mediated Biosensors and Enzyme Assay....Pages 211-230
Poly(Amphiphilic Pyrrole)-Enzyme Electrode: A New Approach for Biosensor Construction....Pages 231-244
Effect of Organic Solvents on the Behaviour of a Glucose Oxidase-Based Biosensor....Pages 245-254
Organic-Phase Biosensors....Pages 255-262
Modified Enzyme Electrodes....Pages 263-269
Can New Biosensors be Deduced from Sensing in Biology ?....Pages 271-280
Microbial Sensors and Microbiosensors....Pages 281-287
Stimulus-Response Measurements on Protein Containing Membranes, Deposited on an ISFET Surface....Pages 289-308
Micro Sensors in Bioelectroanalysis....Pages 309-324
Surface Characteristics of Chemical Sensors....Pages 325-334
Optrodes for Measuring Enzyme Activity and Inhibition....Pages 335-344
Luminescence Detection of Biological Reactions....Pages 345-350
Progress in Fiber-Optic Based Biosensors at the United States Naval Research Laboratory....Pages 351-357
Immobilized Biological Compounds in Defense Applications....Pages 359-368
Biosensors in the Detection of Biological Agents....Pages 369-375
Biosensors for Toxins and Bacteria....Pages 377-385
Reusable Fiber Optic Biosensors for Detection of Drugs and Toxicants....Pages 387-395
The Biosensor Technology Program at the National Institute of Standards and Technology (NIST)....Pages 397-414
FIA Immunoassays with Electrochemical and Optical Detection....Pages 415-419
Immunoassay Devices for Extra-Laboratory Measurements of Toxic Chemicals Based on Capillary Migration and Liposome Amplification....Pages 421-432
Direct Immunoassays: Limitations on the Physical Principles and on the Technology State of the Art....Pages 433-441
Comparison of Different Solid Phases for an Elisa Based Determination of Aflatoxin B....Pages 443-452
Polystyrene and Poly(Styrene/Acrolein) Latexes with Immobilized Proteins as a Basis of the Diagnostic Agglutination Test....Pages 453-462
An Integrated Optical Immunosensor....Pages 463-470
Immobilized Biological Compounds in Food Analysis....Pages 471-476
Immobilized Biomolecules for Detection of Environmental Pollutants....Pages 477-487
Enzyme Inhibition Sensor for Organophosphorus Pesticides Analysis....Pages 489-499
Biosensors for Electrochemical Non Invasive Analysis....Pages 501-514
Flow-Through Biosensors in Clinical Analysis....Pages 515-525
Flow Injection Analysis: A Complementary or Alternative Concept to Biosensors....Pages 527-540
Heat Sensitive Biosensors....Pages 541-548
The Market for Biosensors the Strengths and the Competition....Pages 549-557
Report on Biosensor Technology in Europe....Pages 559-566
Back Matter....Pages 567-577

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Content:
Front Matter....Pages i-xxiii
Immobilization of Biological Species on Bilayer Lipid Membranes....Pages 1-10
Polymeric Environments for Proteins and Whole Cells in Molecular Sensors....Pages 11-21
Use of Red Blood Cells (RBC) as Carriers of Bioactive Compounds....Pages 23-33
Theoretical and Experimental Aspects for Improvement of Electrochemical Biosensors by Various Kinds of Immobilization....Pages 35-45
Development and Characterization of Polymeric Biomaterials for Bioactive Agent Immobilization....Pages 47-56
Two-Dimensional (GLYCO)Protein Crystals as Immobilization Matrix for Functional Molecules....Pages 57-66
Application of Graphite-Epoxy Composites in the Construction of Elctrochemical Sensors and Biosensors....Pages 67-79
Novel Phema Membranes for Potential Bioelectrode use....Pages 81-90
Immobilization of Cell Cycle Specific Drug DFMO for Chemotherapy....Pages 91-99
Use of Immobilized Biological Compounds in Drug Analysis....Pages 101-113
In Vivo Monitoring with Microdialysis Probe....Pages 115-122
Immobilised Catalase and Hydrogen Peroxide — A Novel Contact Lens Disinfection System....Pages 123-130
Ex-Vivo Sensors; Microencapsulation of Enzyme Layer in Biosensors....Pages 131-140
Clinical Application of Biosensing with Amperometric Detection of Ammonia-Nitrogen....Pages 141-150
Therapeutic Potential of Immobilized Enzymes....Pages 151-160
Optimization of Membranes with Glucose Oxidase for Glucose Determination using Oxygen Electrode....Pages 161-170
Multienzyme Biosensors — Coupled Enzyme Reactions and Enzyme Activation....Pages 171-179
Three Different Approaches for Preparing GLOD and GLDH Reactors. Application for the Assay of Glutamates in Real Samples Using a FIA — System....Pages 181-189
Enzyme Immobilization on Chitin and Chitosan for Construction of Enzymatic Sensors....Pages 191-200
Electrochemical Biosensors....Pages 201-210
Novel Approaches to the Development of Mediated Biosensors and Enzyme Assay....Pages 211-230
Poly(Amphiphilic Pyrrole)-Enzyme Electrode: A New Approach for Biosensor Construction....Pages 231-244
Effect of Organic Solvents on the Behaviour of a Glucose Oxidase-Based Biosensor....Pages 245-254
Organic-Phase Biosensors....Pages 255-262
Modified Enzyme Electrodes....Pages 263-269
Can New Biosensors be Deduced from Sensing in Biology ?....Pages 271-280
Microbial Sensors and Microbiosensors....Pages 281-287
Stimulus-Response Measurements on Protein Containing Membranes, Deposited on an ISFET Surface....Pages 289-308
Micro Sensors in Bioelectroanalysis....Pages 309-324
Surface Characteristics of Chemical Sensors....Pages 325-334
Optrodes for Measuring Enzyme Activity and Inhibition....Pages 335-344
Luminescence Detection of Biological Reactions....Pages 345-350
Progress in Fiber-Optic Based Biosensors at the United States Naval Research Laboratory....Pages 351-357
Immobilized Biological Compounds in Defense Applications....Pages 359-368
Biosensors in the Detection of Biological Agents....Pages 369-375
Biosensors for Toxins and Bacteria....Pages 377-385
Reusable Fiber Optic Biosensors for Detection of Drugs and Toxicants....Pages 387-395
The Biosensor Technology Program at the National Institute of Standards and Technology (NIST)....Pages 397-414
FIA Immunoassays with Electrochemical and Optical Detection....Pages 415-419
Immunoassay Devices for Extra-Laboratory Measurements of Toxic Chemicals Based on Capillary Migration and Liposome Amplification....Pages 421-432
Direct Immunoassays: Limitations on the Physical Principles and on the Technology State of the Art....Pages 433-441
Comparison of Different Solid Phases for an Elisa Based Determination of Aflatoxin B....Pages 443-452
Polystyrene and Poly(Styrene/Acrolein) Latexes with Immobilized Proteins as a Basis of the Diagnostic Agglutination Test....Pages 453-462
An Integrated Optical Immunosensor....Pages 463-470
Immobilized Biological Compounds in Food Analysis....Pages 471-476
Immobilized Biomolecules for Detection of Environmental Pollutants....Pages 477-487
Enzyme Inhibition Sensor for Organophosphorus Pesticides Analysis....Pages 489-499
Biosensors for Electrochemical Non Invasive Analysis....Pages 501-514
Flow-Through Biosensors in Clinical Analysis....Pages 515-525
Flow Injection Analysis: A Complementary or Alternative Concept to Biosensors....Pages 527-540
Heat Sensitive Biosensors....Pages 541-548
The Market for Biosensors the Strengths and the Competition....Pages 549-557
Report on Biosensor Technology in Europe....Pages 559-566
Back Matter....Pages 567-577
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