Ebook: Experimental and Theoretical Advances in Biological Pattern Formation

This volume contains the proceedings of the NATO ARW on 'Biological Pattern Formation' held at Merton College, University of Oxford, on 27-31 August, 1992. The objective of the workshop was to bring together a select group of theoreticians and experimental biologists to present the latest results in the area of biological pattern formation and to foster interactiqn across dis- plines. The workshop was divided into 5 main areas: (i) limb development, (ii) Dictyostelium discoideum, (iii) Drosophila, (iv) cell movement, (v) g- eral pattern formation. We thank all the participants for their contributions, enthusiasm, and willingness to collaborate. There was a genuine, open, and extremely fru- ful interaction between the experimentalists and theoreticians which made the workshop a success. We also thank The Welcome Trust for providing additional funding. The local organization fell mainly on Denise McKittrick and Beverley Bhaskhare at the Mathematical Institute, Oxford, and Jeanette Hudson and the staff of Merton College. We greatly appreciate their help and patience. We also thank Jonathan Sherratt, Wendy Brandts and Debbie Benson for helping out in the conference and for providing a happy welcome to parti- pants on a typically cold, wet and windy English summer day.

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Content:
Front Matter....Pages i-ix
General Models of Pattern Formation: Some Uses, Problems and Successes....Pages 1-9
Process and Outcome: Evolutionary Analysis of Morphological Patterns....Pages 11-20
Retinoic Acid cannot be the Morphogen in Reaction-Diffusion Models for the Formation of the Chick Wing Bud....Pages 21-28
Pattern Formation in Heterogeneous Domains....Pages 29-32
A Field Model of Symmetry Reversals in the Pattern Regulation of a Cell....Pages 33-36
Patterning in Limbs: The Resolution of Positional Confrontations....Pages 37-44
The Development of a Spatial Pattern in a Model for Cancer Growth....Pages 45-59
Sequential and Synchronous Skin Pattern Formation....Pages 61-64
Control of Gap Junction Permeability can Control Pattern Formation in Limb Development....Pages 65-81
Wave Patterns in One-Dimensional Nonlinear Degenerate Diffusion Equations....Pages 83-86
Trajectories of Swimming Micro-Organisms and Continuum Models of Bioconvection....Pages 87-99
Testing the Theoretical Models for Limb Patterning....Pages 101-103
The Chicken and the Egg....Pages 105-119
Supercomputer Simulation of Turing Structures in Drosophila Morphogenesis....Pages 121-148
The Role of Hox Genes in Axis Specification....Pages 149-159
Looking at Early Development in Xenopus Laevis Using Nmr Micro-Imaging....Pages 161-181
Mechanism of Local Chaos in Active Distributed Media....Pages 183-190
Patterns Formed Through Cell-Cell Interactions: Spontaneous Selection of Dominant Directions....Pages 191-210
Controlling Reaction-Diffusion Pattern with Gradients: Lessons from Drosophila, and Trajectories Through Parameter Space....Pages 211-221
Steady-State Patterns in a Reaction Diffusion System with Mixed Boundary Conditions....Pages 223-230
Pattern Control in Hydra: Basic Experiments and Concepts....Pages 231-235
Predicted and Observed Spatial Prepatterns in (Hair) Wool Follicle Bulbs....Pages 237-253
The Speed of a Brownian Ratchet....Pages 255-266
Oscillations and Waves in a Model of InsP3-Controlled Calcium Dynamics....Pages 267-276
Four Signals to Shape a Slime Mold....Pages 277-300
Modelling Actin Filament Alignment....Pages 301-318
Retinoic Acid: An Autocatalytic Morphogen....Pages 319-323
The Hardware and Software of Morphogenesis: Studies with the Dictyostelium Discoideum Slug, A Simple Tissue....Pages 325-338
Factors Controlling the Directionality of Mesoderm Cell Migration in the Xenopus Gastrula....Pages 339-344
Analysis and Modelling of the Organization of the Mammalian Cerebral Cortex....Pages 345-354
Back Matter....Pages 355-367
....Pages 369-384