Ebook: Molecular Biology and its Application to Medical Mycology

Presented here are recent achievements in molecular biology of non-pathogenic yeast and filamenous fungi as well as of human pathogens. Thebook is diveded into 4 sections: - Molecular Biology of Yeast; - Molecular Biology of Filamenous Fungi; - New Tools and Prospectives for Medical Mycology; - Fungal Morphogenesis. It focuses on aspects of medical mycology, namely isolation of specific genes and strategies for developing new targets for antifungal therapy.

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Presented here are recent achievements in molecular biology of non-pathogenic yeast and filamenous fungi as well as of human pathogens. Thebook is diveded into 4 sections: - Molecular Biology of Yeast; - Molecular Biology of Filamenous Fungi; - New Tools and Prospectives for Medical Mycology; - Fungal Morphogenesis. It focuses on aspects of medical mycology, namely isolation of specific genes and strategies for developing new targets for antifungal therapy.
Content:
Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Cell cycle regulation in fission yeast....Pages 3-5
Yeast genes overcoming growth arrest induced by 1, 10-phenantroline....Pages 7-11
The complement C3D-binding receptor (CR2) of Candida albicans: Cloning and sequence analysis of a gene fragment homologous with a human CR2 cDNA clone....Pages 13-22
Biology, physiology, biochemistry and molecular genetics of Trichosporon yeasts....Pages 23-30
Physiological functions of vacuoles in yeast: Mechanism of sequestration of metabolites and proteins into vacuoles....Pages 31-38
Characterization of a Candida albicans-specific DNA fragment....Pages 39-45
Gene regulatory circuits in Saccharomyces cerevisiae as a tool for the identification of heterologous eukaryotic regulatory elements....Pages 47-52
Front Matter....Pages 53-61
Expression of genes for the biosynthesis of penicillin....Pages 63-73
Front Matter....Pages 75-83
Imaging of the yeast killer phenomenon....Pages 85-85
cDNA cloning of Candida albicans aspartic proteinase and its diagnostic application....Pages 87-95
Molecular biotyping of Candida in experimental and clinical studies....Pages 97-104
Homoserine dehydrogenase as a selective target molecule for antifungal action....Pages 105-116
Molecular mechanisms of antifungal activity and fungal resistence: focus on inhibitors of ergosterol biosynthesis....Pages 117-124
Front Matter....Pages 125-138
Molecular studies on azole sensitivity in fungi....Pages 139-139
Antifungal chemotherapy and drug strategies: Projected clinical needs....Pages 141-148
Funding medical mycology: Strategies for attracting the private sector....Pages 149-158
Front Matter....Pages 159-168
Back Matter....Pages 169-177
....Pages 179-197