Ebook: Macrophage Biology and Activation

The amazing world of the mononuclear phagocytes keeps expanding at a truly awesome pace. As a result, maintaining currency with the latest developments and controversies that pertain to this cell type is increasingly difficult. The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future. The scope of topics ranges from how these cells develop, through the means that are used to regulate them, to the roles that they have in different tissues and in a variety of infectious diseases.

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The amazing world of the mononuclear phagocytes keeps expanding at a truly awesome pace. As a result, maintaining currency with the latest developments and controversies that pertain to this cell type is increasingly difficult. The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future. The scope of topics ranges from how these cells develop, through the means that are used to regulate them, to the roles that they have in different tissues and in a variety of infectious diseases.

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The amazing world of the mononuclear phagocytes keeps expanding at a truly awesome pace. As a result, maintaining currency with the latest developments and controversies that pertain to this cell type is increasingly difficult. The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future. The scope of topics ranges from how these cells develop, through the means that are used to regulate them, to the roles that they have in different tissues and in a variety of infectious diseases.
Content:
Front Matter....Pages I-IX
Antigen Markers of Macrophage Differentiation in Murine Tissues....Pages 1-37
Macrophages in the Uterus and Placenta....Pages 39-63
Urokinase-Catalyzed Plasminogen Activation at the Monocyte/Macrophage Cell Surface: A Localized and Regulated Proteolytic System....Pages 65-86
Macrophage-Derived Growth Factors....Pages 87-140
The Biology of CSF-1 and Its Receptor....Pages 141-167
Lipopolysaccharide Receptors and Signal Transduction Pathways in Mononuclear Phagocytes....Pages 169-188
The Role of Myristoylated Protein Kinase C Substrates in Intracellular Signaling Pathways in Macrophages....Pages 189-207
Ribosomal RNA Metabolism in Macrophages....Pages 209-237
Mononuclear Phagocytes as Targets, Tissue Reservoirs, and Immunoregulatory Cells in Human Immunodeficiency Virus Disease....Pages 239-263
Interactions Between Macrophages and Legionella pneumophila....Pages 265-282
Chronic Granulomatous Disease: An Update and a Paradigm for the Use of Interferon-? as Adjunct Immunotheraphy in Infectious Diseases....Pages 283-292
Back Matter....Pages 293-299

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The amazing world of the mononuclear phagocytes keeps expanding at a truly awesome pace. As a result, maintaining currency with the latest developments and controversies that pertain to this cell type is increasingly difficult. The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future. The scope of topics ranges from how these cells develop, through the means that are used to regulate them, to the roles that they have in different tissues and in a variety of infectious diseases.
Content:
Front Matter....Pages I-IX
Antigen Markers of Macrophage Differentiation in Murine Tissues....Pages 1-37
Macrophages in the Uterus and Placenta....Pages 39-63
Urokinase-Catalyzed Plasminogen Activation at the Monocyte/Macrophage Cell Surface: A Localized and Regulated Proteolytic System....Pages 65-86
Macrophage-Derived Growth Factors....Pages 87-140
The Biology of CSF-1 and Its Receptor....Pages 141-167
Lipopolysaccharide Receptors and Signal Transduction Pathways in Mononuclear Phagocytes....Pages 169-188
The Role of Myristoylated Protein Kinase C Substrates in Intracellular Signaling Pathways in Macrophages....Pages 189-207
Ribosomal RNA Metabolism in Macrophages....Pages 209-237
Mononuclear Phagocytes as Targets, Tissue Reservoirs, and Immunoregulatory Cells in Human Immunodeficiency Virus Disease....Pages 239-263
Interactions Between Macrophages and Legionella pneumophila....Pages 265-282
Chronic Granulomatous Disease: An Update and a Paradigm for the Use of Interferon-? as Adjunct Immunotheraphy in Infectious Diseases....Pages 283-292
Back Matter....Pages 293-299
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