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Membrane interaction is a large research area involving various disciplines. A symposium entitled "Cell and Model Membrane Interactions" which took place in Boston, MA during the 155th American Chemical Society Meeting, April 25, 1990, focused on membrane adhesion and fusion. The topics were explored in studies involving lipids, virus envelopes and cell membranes. Especially discussed, were the roles of polymers, lipids, and proteins on these membrane interactions. Fusion of membrane is an important molecular event which plays a pivotal role in many dynamic cellular processes, such as exocytosis, endocytosis, membrane genesis, viral infection processes, etc. The process includes adhesion of the mem­ branes, fusion, and finally reorganization of the components of the two membranes. The basic notion shared during the symposium was that membrane hydro­ phobicity, especially local membrane hydrophobicity is one of the important factors contributing to membrane fusion. Most of the papers are collected here and they are arranged approximately in the same order as they were presented at the sympo­ sium. These papers are the most up-to-date and representative work at the forefront in each membrane interaction field. I sincerely hope the reader will gain further understanding on membrane interactions especially, membrane and vesicle fusion phenomena through this symposium proceedings volume.








Content:
Front Matter....Pages i-viii
Determination of Lipid Asymmetry and Exchange in Model Membrane Systems....Pages 1-14
Partitioning of Gramicidin A’ Between Coexisting Phases within Phospholipid Bilayers....Pages 15-24
Membrane Contact Induced Between Erythrocytes by Polycations, Lectins and Dextran....Pages 25-45
Pegylation of Membrane Surfaces....Pages 47-62
Influence of Polar Polymers on the Aggregation and Fusion of Membranes....Pages 63-87
Control of Fusion of Biological Membranes by Phospholipid Asymmetry....Pages 89-113
Annexin-Phospholipid Interactions in Membrane Fusion....Pages 115-134
Biological Consequences of Alterations in the Physical Properties of Membranes....Pages 135-147
Evidence for Multiple Steps in Enveloped Virus Binding....Pages 149-162
Inhibition of Sendai Virus Fusion and Phospholipid Vesicle Fusion: Implications for the Pathway of Membrane Fusion....Pages 163-177
Fusion of Influenza, Sendai and Simian Immunodeficiency Viruses with Cell Membranes and Liposomes....Pages 179-197
Red Blood Cell Interaction with a Glass Surface....Pages 199-213
On the Mechanism of Membrane Fusion: Use of Synthetic Surfactant Vesicles as a Novel Model System....Pages 215-228
Kinetics of Intermembrane Interactions Leading to Fusion....Pages 229-247
Short-Range Repulsive Interactions between the Surfaces of Lipid Membranes....Pages 249-265
Physico-Chemical Factors Underlying Membrane Adhesion and Fusion....Pages 267-283
Back Matter....Pages 285-290



Content:
Front Matter....Pages i-viii
Determination of Lipid Asymmetry and Exchange in Model Membrane Systems....Pages 1-14
Partitioning of Gramicidin A’ Between Coexisting Phases within Phospholipid Bilayers....Pages 15-24
Membrane Contact Induced Between Erythrocytes by Polycations, Lectins and Dextran....Pages 25-45
Pegylation of Membrane Surfaces....Pages 47-62
Influence of Polar Polymers on the Aggregation and Fusion of Membranes....Pages 63-87
Control of Fusion of Biological Membranes by Phospholipid Asymmetry....Pages 89-113
Annexin-Phospholipid Interactions in Membrane Fusion....Pages 115-134
Biological Consequences of Alterations in the Physical Properties of Membranes....Pages 135-147
Evidence for Multiple Steps in Enveloped Virus Binding....Pages 149-162
Inhibition of Sendai Virus Fusion and Phospholipid Vesicle Fusion: Implications for the Pathway of Membrane Fusion....Pages 163-177
Fusion of Influenza, Sendai and Simian Immunodeficiency Viruses with Cell Membranes and Liposomes....Pages 179-197
Red Blood Cell Interaction with a Glass Surface....Pages 199-213
On the Mechanism of Membrane Fusion: Use of Synthetic Surfactant Vesicles as a Novel Model System....Pages 215-228
Kinetics of Intermembrane Interactions Leading to Fusion....Pages 229-247
Short-Range Repulsive Interactions between the Surfaces of Lipid Membranes....Pages 249-265
Physico-Chemical Factors Underlying Membrane Adhesion and Fusion....Pages 267-283
Back Matter....Pages 285-290
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