Ebook: Progress in Vaccinology

This second volume of the new series on vaccinology is devoted broadly to vaccines against communicable diseases. Key issues discuss the practicability and efficacy of universal vaccination and the benefits for public health especially in developing countries. Chapters concerning problems with storage of supplies of vaccines in active form, and new technologies applied to the manufacturing of vaccines are included. Epidemiological studies and prospects as well as various immunological parameters concerning the diagnosis, course and prevention of various viral, bacterial and parasitological diseases such as hepatology, cholera, helminthic infections, lepra and others are comprehensively treated by experts in their respective fields. New approaches in vaccinology such as the use of Vaccinia Virus as vector or the use of liposomes as carrier of vaccines are discussed.

---

This second volume of the new series on vaccinology is devoted broadly to vaccines against communicable diseases. Key issues discuss the practicability and efficacy of universal vaccination and the benefits for public health especially in developing countries. Chapters concerning problems with storage of supplies of vaccines in active form, and new technologies applied to the manufacturing of vaccines are included. Epidemiological studies and prospects as well as various immunological parameters concerning the diagnosis, course and prevention of various viral, bacterial and parasitological diseases such as hepatology, cholera, helminthic infections, lepra and others are comprehensively treated by experts in their respective fields. New approaches in vaccinology such as the use of Vaccinia Virus as vector or the use of liposomes as carrier of vaccines are discussed.
Content:
Front Matter....Pages i-xx
Front Matter....Pages N1-N1
Vaccinology: The Two Revolutions....Pages 1-3
Front Matter....Pages N2-N2
Vaccinology and the Goal of Health for All....Pages 5-14
Toward Universal Immunization: 1990....Pages 15-21
New and Improved Techniques for Vaccine Production....Pages 23-36
Transfer of Vaccine Production to the Developing World: Rabies Vaccine....Pages 37-39
Policy for Developing Countries for Storage, Distribution, and Use of Essential Vaccines for Immunoprophylaxis....Pages 41-46
Front Matter....Pages N3-N3
Immunity in Tuberculosis: Environmental Versus Intrinsic Factors Modulating the Immune Responsiveness to Mycobacteria....Pages 47-60
Geographic Variation in Vaccine Efficacy: The Polio Experience....Pages 61-66
Front Matter....Pages N4-N4
Molecular Immunology of Viral Antigens in Hepatitis B Vaccination....Pages 67-81
Biologic Significance of Pre-S Antigen and Anti-Pre-S Antibodies in Hepatitis B Virus Infection....Pages 83-91
Enterically Transmitted Hepatitis Viruses: Prospects for Control....Pages 93-100
Immunological Characterization of a Viral Agent Involved in Epidemic and Sporadic Non-A Non-B Hepatitis....Pages 101-111
Front Matter....Pages N5-N5
Attenuated Oral Typhoid Vaccine Ty 21a....Pages 113-117
Oral B Subunit-Whole Cell Vaccine Against Cholera: From Basic Research to Successful Field Trial....Pages 119-130
Prospects of Immunization Against Cholera by Adhesive Antigen....Pages 131-136
Rationale for the Development of a Rotavirus Vaccine for Infants and Young Children....Pages 137-150
Mucosal Immunity in the Gastrointestinal Tract in Relation to ETEC Vaccine Development....Pages 151-180
Shigella Vaccines....Pages 181-196
Front Matter....Pages 197-204
Mucosal and Acquired Immunity in Giardiasis and Its Relation to Diarrhea and Malabsorption....Pages 205-215
Immunology of Entamoeba histolytica in Human and Experimental Hosts....Pages N5-N5
Molecular Comparisons Among Entamoeba histolytica Strains Using DNA and Protein Profiles....Pages 217-226
Front Matter....Pages 227-251
Importance of Antibody Class in Helminth Infections....Pages 253-258
Immunodiagnosis of Filariasis....Pages N6-N6
Front Matter....Pages 259-274
Development, Production, and Application of Vaccines in Foot-and-Mouth Disease Control in India....Pages 275-281
Cell Culture Vaccine Against Bovine Tropical Theileriosis....Pages N7-N7
Front Matter....Pages 283-296
Present Approaches to Immunotherapy and Immunoprophylaxis for Leprosy....Pages 297-300
Armadillo-Derived Killed M. leprae: Candidate Vaccine Against Leprosy....Pages N8-N8
Molecular Approaches to Developing a Vaccine for Leprosy....Pages 301-311
Immunodiagnosis of Leprosy....Pages 313-321
Immunodiagnostic Approaches to the Detection of M. leprae Infection in Leprosy....Pages 323-333
Serological Survey of Leprosy Using a Monoclonal Antibody-Based Immunoassay and Phenolic Glycolipid ELISA....Pages 335-346
Front Matter....Pages 347-354
Antisporozoite Malaria Vaccine Development Based on Circumsporozoite Protein....Pages 355-365
Malaria Sporozoite Vaccine Development: Recent Progress....Pages 367-376
Community-Based Integrated Vector Control of Malaria in India....Pages N9-N9
Leishmaniasis and Malaria: New Tools for Epidemiological Analysis....Pages 377-385
Front Matter....Pages 387-392
Vaccinia Virus Expression Vectors....Pages 393-399
Vaccinia Recombinants Expressing Foreign Antigens: Antiviral and Antitumor Immunity....Pages 401-413
Front Matter....Pages N10-N10
Liposomes as Carriers of Vaccines....Pages 415-421
A Short Primer on Vaccine Design: Focus on the Interrelatedness of Antigenic Determinants Addressing Various Lymphocyte Subpopulations....Pages 423-428
Next Steps in the Evolution of Vaccinology....Pages N10-N10
Back Matter....Pages 429-437
....Pages 439-449