Ebook: Zinc in Human Biology

The present volume is one of a series concerned with topics considered to be of growing interest to those whose ultimate aim is the understanding of the nutrition of man. Volumes on Sweetness, Calcium in Human Biology and Sucrose: Nutritional and Safety Aspects, have already been published, and another, on Dietary Starches and Sugars in Man: A Comparison, is in preparation. Written for workers in the nutritional and allied sciences rather than for the specialist, they aim to fill the gap between the textbook on the one hand and the many publications addressed to the expert on the other. The target readership spans medicine, nutrition and the biological sciences generally and includes those in the food, chemical and allied industries who need to take account of advances in these fields relevant to their products. Funded by industry but with an independent status, the Inter­ national Life Sciences Institute (ILSI) is a non-profit organization founded to deal objectively with the numerous health and safety issues that today concern industry internationally. ILSI sponsors scientific research, organizes conferences and publishes monographs relative to these problems. London Ian Macdonald March 1988 Series Editor Preface This volume has been prepared at a time when interest in both the biological roles of zinc and its nutritional significance is growing rapidly.

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Zinc in Human Biology describes the functions of zinc in the maintenance of health, physiological development and growth. It highlights the importance of factors which govern the utilization of dietary zinc and thus influence susceptibility to zinc deficiency. Of particular note are its critical reviews of controversial reports on the epidemiological significance of zinc. Emphasis is also given to the practical difficulty of achieving an unequivocal diagnosis of zinc deficiency when susceptibility is influenced strongly by environmental and nutritional factors which aggravate or ameliorate clinical responses.

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Zinc in Human Biology describes the functions of zinc in the maintenance of health, physiological development and growth. It highlights the importance of factors which govern the utilization of dietary zinc and thus influence susceptibility to zinc deficiency. Of particular note are its critical reviews of controversial reports on the epidemiological significance of zinc. Emphasis is also given to the practical difficulty of achieving an unequivocal diagnosis of zinc deficiency when susceptibility is influenced strongly by environmental and nutritional factors which aggravate or ameliorate clinical responses.
Content:
Front Matter....Pages i-xix
Physiology of Zinc: General Aspects....Pages 1-14
An Introduction to the Biochemistry of Zinc....Pages 15-31
Intestinal Absorption of Zinc....Pages 33-55
Promoters and Antagonists of Zinc Absorption....Pages 57-78
Systemic Transport of Zinc....Pages 79-93
Systemic Interactions of Zinc....Pages 95-108
Biochemistry of Zinc in Cell Division and Tissue Growth....Pages 109-118
Zinc in Cell Division and Tissue Growth: Physiological Aspects....Pages 119-128
Biochemical Pathologies of Zinc Deficiency....Pages 129-145
Zinc and Iron in Free Radical Pathology and Cellular Control....Pages 147-172
Zinc Status and Food Intake....Pages 173-181
Zinc and Reproduction: Effects of Deficiency on Foetal and Postnatal Development....Pages 183-220
A Note on Zinc and Immunocompetence....Pages 221-223
Zinc and Behaviour....Pages 225-234
Neurobiology of Zinc....Pages 235-247
Zinc in Endocrine Function....Pages 249-258
Severe Zinc Deficiency....Pages 259-279
Mild Zinc Deficiency in Human Subjects....Pages 281-296
Putative Therapeutic Roles for Zinc....Pages 297-321
The Diagnosis of Zinc Deficiency....Pages 323-333
Human Zinc Requirements....Pages 335-350
Dietary Pattern and Zinc Supply....Pages 351-363
Zinc Excess....Pages 365-370
The Biological Significance of Zinc for Man: Problems and Prospects....Pages 371-381
Back Matter....Pages 382-388

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Zinc in Human Biology describes the functions of zinc in the maintenance of health, physiological development and growth. It highlights the importance of factors which govern the utilization of dietary zinc and thus influence susceptibility to zinc deficiency. Of particular note are its critical reviews of controversial reports on the epidemiological significance of zinc. Emphasis is also given to the practical difficulty of achieving an unequivocal diagnosis of zinc deficiency when susceptibility is influenced strongly by environmental and nutritional factors which aggravate or ameliorate clinical responses.
Content:
Front Matter....Pages i-xix
Physiology of Zinc: General Aspects....Pages 1-14
An Introduction to the Biochemistry of Zinc....Pages 15-31
Intestinal Absorption of Zinc....Pages 33-55
Promoters and Antagonists of Zinc Absorption....Pages 57-78
Systemic Transport of Zinc....Pages 79-93
Systemic Interactions of Zinc....Pages 95-108
Biochemistry of Zinc in Cell Division and Tissue Growth....Pages 109-118
Zinc in Cell Division and Tissue Growth: Physiological Aspects....Pages 119-128
Biochemical Pathologies of Zinc Deficiency....Pages 129-145
Zinc and Iron in Free Radical Pathology and Cellular Control....Pages 147-172
Zinc Status and Food Intake....Pages 173-181
Zinc and Reproduction: Effects of Deficiency on Foetal and Postnatal Development....Pages 183-220
A Note on Zinc and Immunocompetence....Pages 221-223
Zinc and Behaviour....Pages 225-234
Neurobiology of Zinc....Pages 235-247
Zinc in Endocrine Function....Pages 249-258
Severe Zinc Deficiency....Pages 259-279
Mild Zinc Deficiency in Human Subjects....Pages 281-296
Putative Therapeutic Roles for Zinc....Pages 297-321
The Diagnosis of Zinc Deficiency....Pages 323-333
Human Zinc Requirements....Pages 335-350
Dietary Pattern and Zinc Supply....Pages 351-363
Zinc Excess....Pages 365-370
The Biological Significance of Zinc for Man: Problems and Prospects....Pages 371-381
Back Matter....Pages 382-388
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