Ebook: Improving Genetic Disease Resistance in Farm Animals

This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics". The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.

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Content:
Front Matter....Pages i-viii
Front Matter....Pages 1-1
Introduction....Pages 3-5
Biological Significance of the MHC....Pages 6-12
Front Matter....Pages 13-13
The Characterisation and Function of the Bovine MHC....Pages 15-22
Current Status of SLA Class I And II Serology....Pages 23-32
Ela(Equine Lymphocyte Alloantigens) Serology and Genetics....Pages 33-41
The Chicken MHC and its Importance+ ....Pages 42-62
Some Evidence for The Presence of an MHC Analogue in Fish....Pages 63-71
Front Matter....Pages 73-73
Bola Polymorphism, Biochemical Analysis at the Product Level....Pages 75-80
Comparison of BoLa Class I and Class II Typing Methods and their Application to MHC Function Studies....Pages 81-90
The Molecular Genetics of the Sla Complex....Pages 91-98
Molecular Anatomy of the Chicken Major Histocompatibilty B Complex....Pages 99-103
Front Matter....Pages 105-105
Possible Influence of the Caprine Leucocyte Antigen (CLA) System on Development of Caprine Arthritis Encephalitis (CAE) in Family and Population Studies....Pages 107-114
Statistical Aspects of Cattle MHC (Bola) and Disease Associations Exemplified by an Investigation of Subclinical Mastitis....Pages 115-123
Possible Effects of the Pig SLA Complex on Physiological Performances....Pages 124-133
Ela Disease Associations....Pages 134-142
Front Matter....Pages 143-143
An Immune Competence Profile in Swine....Pages 145-152
The Genetics of Parasite Resistance in Sheep....Pages 153-159
The Biozzi Model Applied to the Chicken....Pages 160-168
Genetic Resistance to Bovine Mastitis....Pages 169-177
Front Matter....Pages 179-179
General Discussion and Conclusions....Pages 181-184

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Content:
Front Matter....Pages i-viii
Front Matter....Pages 1-1
Introduction....Pages 3-5
Biological Significance of the MHC....Pages 6-12
Front Matter....Pages 13-13
The Characterisation and Function of the Bovine MHC....Pages 15-22
Current Status of SLA Class I And II Serology....Pages 23-32
Ela(Equine Lymphocyte Alloantigens) Serology and Genetics....Pages 33-41
The Chicken MHC and its Importance+ ....Pages 42-62
Some Evidence for The Presence of an MHC Analogue in Fish....Pages 63-71
Front Matter....Pages 73-73
Bola Polymorphism, Biochemical Analysis at the Product Level....Pages 75-80
Comparison of BoLa Class I and Class II Typing Methods and their Application to MHC Function Studies....Pages 81-90
The Molecular Genetics of the Sla Complex....Pages 91-98
Molecular Anatomy of the Chicken Major Histocompatibilty B Complex....Pages 99-103
Front Matter....Pages 105-105
Possible Influence of the Caprine Leucocyte Antigen (CLA) System on Development of Caprine Arthritis Encephalitis (CAE) in Family and Population Studies....Pages 107-114
Statistical Aspects of Cattle MHC (Bola) and Disease Associations Exemplified by an Investigation of Subclinical Mastitis....Pages 115-123
Possible Effects of the Pig SLA Complex on Physiological Performances....Pages 124-133
Ela Disease Associations....Pages 134-142
Front Matter....Pages 143-143
An Immune Competence Profile in Swine....Pages 145-152
The Genetics of Parasite Resistance in Sheep....Pages 153-159
The Biozzi Model Applied to the Chicken....Pages 160-168
Genetic Resistance to Bovine Mastitis....Pages 169-177
Front Matter....Pages 179-179
General Discussion and Conclusions....Pages 181-184
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