Ebook: Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy

Contents/Information: N.P. Johnson, J.-L. Butour, G. Villani, F.L. Wimmer, M. Defais, V. Pierson, Toulouse, France; V. Brabec, Kralovopolska, CSSR: Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes Pertaining to the Design of Anticancer AgentsB.K. Keppler, M. Henn, U.M. Juhl, M.R. Berger, R. Niebl, Heidelberg; F.E. Wagner, Garching, FRG: New Ruthenium Complexes for the Treatment of CancerG. Mestroni, E. Alessio, Trieste, M. Calligaris, Pavia, Italy; W.M. Attia, Ismailia, Egypt; F. Quadrifoglio, S. Cauci, Udine, Italy; G. Sava, S. Zorzet, S. Pacor, C. Monti-Bragadin, M. Tamaro, L. Dolzani, Trieste, Italy: Chemical, Biological and Antitumor Properties of Ruthenium (II) Complexes with DimethylsulfoxideN. Farrell, Burlington/VT, USA: Metal Complexes as RadiosensitizersS.C. Srivastava, L.F. Mausner, M.J. Clarke, Upton/NY, and Chestnut Hill/MA, USA: Radioruthenium-Labeled Compounds for Diagnostic Tumor ImagingP. Kopf-Maier, Berlin, FRG: The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl ComplexesE.V. Scott, G. Zon, L.G. Marzilli, Atlanta/GA and Foster City/CA, USA: NMR Relaxation Footprinting: The ACr(NH3)6U3+ Cation as a Probe for Drug Binding Sites on OligonucleotidesJ.E. Schurig, H.A. Meinema, K. Timmer, Wallingford/CT, USA; B.H. Long, A.M. Casazza, Zeist, NL: Antitumor Activity of BisABis(Diphenylphosphino)Alkane and AlkeneU Group VIII Metal ComplexesM.E. Heim, H. Flechtner, Mannheim; B.K. Keppler, Heidelberg, FRG: Clinical Studies with Budotitane -A New Non-Platinum Metal Complex for Cancer Therapy

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Contents/Information: N.P. Johnson, J.-L. Butour, G. Villani, F.L. Wimmer, M. Defais, V. Pierson, Toulouse, France; V. Brabec, Kralovopolska, CSSR: Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes Pertaining to the Design of Anticancer AgentsB.K. Keppler, M. Henn, U.M. Juhl, M.R. Berger, R. Niebl, Heidelberg; F.E. Wagner, Garching, FRG: New Ruthenium Complexes for the Treatment of CancerG. Mestroni, E. Alessio, Trieste, M. Calligaris, Pavia, Italy; W.M. Attia, Ismailia, Egypt; F. Quadrifoglio, S. Cauci, Udine, Italy; G. Sava, S. Zorzet, S. Pacor, C. Monti-Bragadin, M. Tamaro, L. Dolzani, Trieste, Italy: Chemical, Biological and Antitumor Properties of Ruthenium (II) Complexes with DimethylsulfoxideN. Farrell, Burlington/VT, USA: Metal Complexes as RadiosensitizersS.C. Srivastava, L.F. Mausner, M.J. Clarke, Upton/NY, and Chestnut Hill/MA, USA: Radioruthenium-Labeled Compounds for Diagnostic Tumor ImagingP. Kopf-Maier, Berlin, FRG: The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl ComplexesE.V. Scott, G. Zon, L.G. Marzilli, Atlanta/GA and Foster City/CA, USA: NMR Relaxation Footprinting: The ACr(NH3)6U3+ Cation as a Probe for Drug Binding Sites on OligonucleotidesJ.E. Schurig, H.A. Meinema, K. Timmer, Wallingford/CT, USA; B.H. Long, A.M. Casazza, Zeist, NL: Antitumor Activity of BisABis(Diphenylphosphino)Alkane and AlkeneU Group VIII Metal ComplexesM.E. Heim, H. Flechtner, Mannheim; B.K. Keppler, Heidelberg, FRG: Clinical Studies with Budotitane -A New Non-Platinum Metal Complex for Cancer Therapy
Content:
Front Matter....Pages i-ix
Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes....Pages 1-24
Ruthenium Chemistry Pertaining to the Design of Anticancer Agents....Pages 25-39
New Ruthenium Complexes for the Treatment of Cancer....Pages 41-69
Chemical, Biological and Antitumor Properties of Ruthenium(II) Complexes with Dimethylsulfoxide....Pages 71-87
Metal Complexes as Radiosensitizers....Pages 89-109
Radioruthenium-Labeled Compounds for Diagnostic Tumor Imaging....Pages 111-149
The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl Complexes....Pages 151-184
NMR Relaxation Footprinting: The [Cr(NH3)6]3+ Cation as a Probe for Drug Binding Sites on Oligonucleotides....Pages 185-204
Antitumor Activity of Bis[Bis(Diphenylphosphino)Alkane and Alkene] Group VIII Metal Complexes....Pages 205-216
Clinical Studies with Budotitane — A New Non-Platinum Metal Complex for Cancer Therapy....Pages 217-223
Back Matter....Pages 225-226

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Contents/Information: N.P. Johnson, J.-L. Butour, G. Villani, F.L. Wimmer, M. Defais, V. Pierson, Toulouse, France; V. Brabec, Kralovopolska, CSSR: Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes Pertaining to the Design of Anticancer AgentsB.K. Keppler, M. Henn, U.M. Juhl, M.R. Berger, R. Niebl, Heidelberg; F.E. Wagner, Garching, FRG: New Ruthenium Complexes for the Treatment of CancerG. Mestroni, E. Alessio, Trieste, M. Calligaris, Pavia, Italy; W.M. Attia, Ismailia, Egypt; F. Quadrifoglio, S. Cauci, Udine, Italy; G. Sava, S. Zorzet, S. Pacor, C. Monti-Bragadin, M. Tamaro, L. Dolzani, Trieste, Italy: Chemical, Biological and Antitumor Properties of Ruthenium (II) Complexes with DimethylsulfoxideN. Farrell, Burlington/VT, USA: Metal Complexes as RadiosensitizersS.C. Srivastava, L.F. Mausner, M.J. Clarke, Upton/NY, and Chestnut Hill/MA, USA: Radioruthenium-Labeled Compounds for Diagnostic Tumor ImagingP. Kopf-Maier, Berlin, FRG: The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl ComplexesE.V. Scott, G. Zon, L.G. Marzilli, Atlanta/GA and Foster City/CA, USA: NMR Relaxation Footprinting: The ACr(NH3)6U3+ Cation as a Probe for Drug Binding Sites on OligonucleotidesJ.E. Schurig, H.A. Meinema, K. Timmer, Wallingford/CT, USA; B.H. Long, A.M. Casazza, Zeist, NL: Antitumor Activity of BisABis(Diphenylphosphino)Alkane and AlkeneU Group VIII Metal ComplexesM.E. Heim, H. Flechtner, Mannheim; B.K. Keppler, Heidelberg, FRG: Clinical Studies with Budotitane -A New Non-Platinum Metal Complex for Cancer Therapy
Content:
Front Matter....Pages i-ix
Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes....Pages 1-24
Ruthenium Chemistry Pertaining to the Design of Anticancer Agents....Pages 25-39
New Ruthenium Complexes for the Treatment of Cancer....Pages 41-69
Chemical, Biological and Antitumor Properties of Ruthenium(II) Complexes with Dimethylsulfoxide....Pages 71-87
Metal Complexes as Radiosensitizers....Pages 89-109
Radioruthenium-Labeled Compounds for Diagnostic Tumor Imaging....Pages 111-149
The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl Complexes....Pages 151-184
NMR Relaxation Footprinting: The [Cr(NH3)6]3+ Cation as a Probe for Drug Binding Sites on Oligonucleotides....Pages 185-204
Antitumor Activity of Bis[Bis(Diphenylphosphino)Alkane and Alkene] Group VIII Metal Complexes....Pages 205-216
Clinical Studies with Budotitane — A New Non-Platinum Metal Complex for Cancer Therapy....Pages 217-223
Back Matter....Pages 225-226
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