Ebook: Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth

The objective of this workshop was to examine the nature of plasma membrane electron transport and how this electron transport contributes to growth of cells. The workshop came at a time when the study of the plasma membrane oxidoreductase activity was beginning to attract more widespread attention from researchers working with both plants and animals. The rapid response of c fos and c myc Proto-oncogene to stimulation of plasma membrane redox activity by external oxidants under­ scores a potential role of plasma membrane oxidoreductases in growth control. Other experiments with isolated endosomes in­ dicate emerging roles in endocytosis and lytic processes. Primary attention was focused on trans plasma membrane electron transport which brings about the oxidation of cytosolic, NADH, NADPH or other substrates by electron flow across the plasma membrane to external oxidants including ferric iron, semide­ hydroascorbate or oxygen. A major theme in the workshop was the relation of this electron flow to pH changes of the cytoplasm or the transfer of protons to the external medium. The presence and role of other oxidoreductases in the plasma membrane was documented, especially in regard to peroxide production. In plant cells this may contribute to cellular defense against invading para­ sites. A corresponding function in animals has been long known and extensively discussed but was beyond the scope of this workshop.

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Content:
Front Matter....Pages i-xv
Introductory Remarks....Pages 1-5
Modulation of Redox Reactions Involved in DNA Synthesis by Oxygen and Artificial Electron Acceptors....Pages 7-16
Redox Agents which Modulate the Growth of Melanoma Cells: Evaluation of Mechanisms....Pages 17-26
Possible Role of Transplasma Membrane Ferricyanide Reductase in Mitogenic Activation of Rat Liver Cells....Pages 27-36
The Requirement for Transmembranal Electron Flow for Cell Proliferation....Pages 37-44
Roles for Plasma Membrane Redox Systems in Cell Growth....Pages 45-55
Redox Components in the Plant Plasma Membrane....Pages 57-69
Reduction-Oxidation Activities of Plant Plasmamembranes....Pages 71-80
Purification of NADH-Ferricyanide and NADH-Duroquinone Reductases from Maize (Zea mays L.) Root Plasma Membranes....Pages 81-88
The Turbo Reductase in Plant Plasma Membranes....Pages 89-93
Specific Interaction of the Herbicide Sethoxydim with the Plasmalemma Redox System of Plant Cells....Pages 95-104
NADH or NADPH ?....Pages 105-114
Mechanism and Control of Iron Uptake by Erythroid and Non-Erythroid Cells....Pages 115-116
The Release of Iron from a Subfraction of Rat Liver Highly Enriched in Endosomal Organelles Requires Both a Functional H+-ATPase and NADH....Pages 117-126
Uptake of Iron from Ferric Iron Compounds by Isolated Hepatocytes....Pages 127-133
Hepatocyte Iron Uptake - A Plasma Membrane Process or an Endosomal Process ?....Pages 135-137
Reductive Release of Iron From Transferrin and Receptor Mediated Recycling....Pages 139-151
Transplasma Membrane Electron Transport Functions as a Ferric Reductase....Pages 153-161
Modulation of Transferrin Receptor Gene Expression by Peptide Growth Factors and Role of the Receptor in Human Fibroblasts....Pages 163-171
Basic and Clinical Studies of Transferrin-Adriamycin Conjugates: Mechanisms for a New Approach to Drug Targeting....Pages 173-180
Control of Transplasma Membrane Diferric Transferrin Reductase by Antitumor Drugs....Pages 181-190
A General Introduction to the Link between Redox Reactions and Proton Gradients....Pages 191-197
Regulation of Proton Diffusion Pathways in Chloroplast Thylakoids by Ca++ Gating....Pages 199-208
Mechanisms of Ion Transport in Plants: K+ as an Example....Pages 209-217
Electron Transport at the Plasma Membrane and ATP-Driven H+ Extrusion in Elodea densa Leaves....Pages 219-232
The Relationships Between Ferricyanide Reduction and Associated Proton Efflux in Mechanically Isolated Photosynthetically Competent Mesophyll Cells....Pages 233-241
Ferricyanide Changes the Transport Properties of Lamprothamnium Papulosum Plasmalemma....Pages 243-252
b-Type Cytochromes, Light- and NADH-Dependent Oxido-Reductase Activities in Plant Plasma Membranes....Pages 253-262
Kinetics of Redox State as Related to Plant Growth and Development....Pages 263-271
Regulation of Transplasmalemma Electron Transport by Calcium and Light in Oat Mesophyll Cells....Pages 273-282
Thioredoxin and Glutaredoxin: Functions in Growth-Dependent DNA Synthesis and Cellular Regulation Via Thiol Redox Control....Pages 283-285
Cytochrome b561 and the Maintenance of Redox Poise in Secretory Vesicles....Pages 287-293
The Retinoic Acid-Induced Cascade of Events Leading to Granulocyte Differentiation in HL60 through a Postulated GTP-Regulated Inducing Molecule....Pages 295-302
Changes in Plasmalemma Functions Induced by Phytopathogenic Bacteria....Pages 303-312
On the Occurrence of Oxidoreductases in the Apoplast of Leguminosae and Gramineae and their Significance in the Study of Plasmamembrane-Bound Redox Activities....Pages 313-321
Relationship between NAD+/NADH Levels and Animal Cell Growth....Pages 323-332
Redox Control of Glutathione and Thioredoxin Reductases....Pages 333-337
Cardiac Ca2+ Channels and Sarcolemma Redox....Pages 339-347
Role of Na+/H+-Antiporter in Growth Stimulation by Ha-ras....Pages 349-358
Protein Kinase C: Plasma Membrane to Nucleus....Pages 359-368
Plasma Membrane Cytochrome Components: Midpoint Redoxpotentials, Light- and NADH Mediated Reductions....Pages 369-381
Localisation of Donor and Acceptor Sites of NAD(P)H Dehydrogenase(S) Using “Inside-Out” and “Right-Side-Out” Plant Plasma Membrane Vesicles, and Characterization of Plasma Membrane-Bound b-Cytochromes....Pages 383-393
NADH-Ferricyanide Oxidoreductase Activity in Maize Root Cell Plasma Membrane....Pages 395-396
The Effect of Sethoxydim on the NAD(P)H Oxidation Associated with Isolated Plasmalemma Vesicles....Pages 397-398
The Resolution of Two Phases of Ferricyanide Reduction in Cultured Carrot Cells....Pages 399-399
Modification of Plasma Membrane DT-Diaphorase Activity Upon Transformation: A Comparison between Astrocytes in Primary Culture and C6 Glioblastoma Cells....Pages 400-400
Transplasma — Membrane Redox System in Erythrocyte Ghosts....Pages 401-401
Stimulation of NADH-Cytochrome C Oxidoreductase of Endoplasmic Reticulum Transitional Elements by Retinol....Pages 402-402
NADH-Dehydrogenases in Synaptic Plasma Membranes....Pages 403-403
Are Plasmalemma Redox Protons Involved in Growth Control by Plant Cells?....Pages 404-405
Is the Proton Extrusion Coupled to Ferricyanide Reduction Mediated by the H + -ATPase ?....Pages 406-407
Relationship of Plasma Membrane Redox Activity to Proton Transport in Roots of Iron-Deficient Cucumber....Pages 408-408
Intracellular pH Modifications Linked to the Activity of the Ferricyanide Driven Activity of the Plasmalemma Redox System in Elodea densa Leaves, Acer pseudoplatanus and Catharanthus roseus Cells....Pages 409-409
Preliminary Evidence for a Regulation of the Plasma Membrane Redox Chain by the Activity of the ATP-Driven H+ Pump in Elodea Densa Leaves....Pages 410-411
Relationship between Auxin-Dependent Proton Extrusion and Plasmalemma Redox System in Maize Coleoptile Segments....Pages 412-412
Possible Exploitation of an H+ Related Mechanism in the Treatment of Breast and Colon Tumors: A New Approach to the Adjuvant Treatment of Cancer....Pages 413-413
Control of Sodium/Proton Exchange by Plasma Membrane Electron Transport....Pages 414-414
Nitrate Uptake by Intact Sunflower Plants....Pages 415-418
Metabolic Changes Associated with Ferricyanide Reduction by Elodea Leaves....Pages 419-420
Stimulation of C-fos and C-myc Proto-Oncogene Expression by Ferricyanide, an Extracellular Electron Acceptor....Pages 421-421
Effeects of PMA on Protein Kinase C in Perfused Rat Heart....Pages 422-422
Anion Superoxide and Hydrogen Peroxide Formation Elicited by NAD(P)H Oxidation in Radish Plasmalemma Vesicles....Pages 423-423
Ascorbate Free Radical Involvement in Elongation-Related Growth Processes in Onion Roots....Pages 424-425
Role of Cell Surface on NADH-MDHA-Oxidoreductase: Lectin Inhibition....Pages 426-426
Iron Reduction by Sunflower Roots under Iron Stress....Pages 427-427
Iron-Stress in Tomato (Lycopersicum esculentum cv. Rutgers) Results in Increased Iron Reduction on the Root Plasma Membrane....Pages 428-428
Back Matter....Pages 429-429
....Pages 430-430