Ebook: Host-Parasite Relationships and the Yersinia Model
- Tags: Medical Microbiology, Zoology, Ecology, Internal Medicine, Allergology, Immunology
- Series: Springer Series in Molecular Biology
- Year: 1986
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects oflife at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macro molecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of informa tion with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective what is known about the field today - and a description of the frontiers of research where our knowledge is increasing steadily.
Content:
Front Matter....Pages I-XI
Front Matter....Pages 1-2
Microorganisms....Pages 3-8
Host-Parasite Relationship....Pages 9-11
Localization of Virulence Determinants....Pages 12-15
Superficial Infection With or Without Toxinogenesis....Pages 16-34
Exudative (Partially Invasive) Infections....Pages 35-49
Invasive (Penetrating) Infections (Except Yersiniosis)....Pages 50-75
Summary....Pages 76-81
Front Matter....Pages 79-80
Recognition by the Immune System....Pages 82-85
The Mechanisms for Maintenance of Self-Integrity....Pages 86-89
Superficial Defense....Pages 90-95
The Role of Body Temperature: Fever and Reduced Iron....Pages 96-105
The Defensive Role of Normal Microbial Flora....Pages 106-114
The Nonspecific Humoral Components....Pages 115-130
Specific Humoral Components: Immunoglobulins....Pages 131-137
Genesis and Distribution of Cellular Components with Defensive Functions....Pages 138-146
Extracellular and Intracellular Destruction of Microorganisms....Pages 147-158
Inflammation, as a Defense Mechanism....Pages 159-163
Genetic Regulation of Defense Mechanisms: Cell-Mediated Immunity in Particular....Pages 164-172
Summary....Pages 173-175
Front Matter....Pages 177-180
Front Matter....Pages 181-184
Other Mechanisms of Yersinia Organism Functioning for Expression of Their Virulence....Pages 177-180
Host Resistances to Yersinia Organisms — Immunology in Yersinia Infection....Pages 185-234
The Phylogenetic Influence of Yersinia Infection on Human Major Histocompatibility Complex (HLA)....Pages 235-256
Summary....Pages 257-291
Back Matter....Pages 292-295
....Pages 296-300