Ebook: Chromosomal Proteins and Gene Expression

This book stems from an Advanced Study Institute on Chromo­ somal Proteins and Gene Expression that was held in Sitges, Spain, on September 17-26, 1984. It would be misleading to call this volume a conference proceedings, however. The ASI was not a conference, but a course with diverse activities, only one of which was a set of major presentations by the lecturers. Indeed, the concept of lecturer was intentionally obscured as we all learned from each other through shorter presentations by other participants and through seminars, poster sessions, and small group discussions. Furthermore, many participants found that exchanging ideas outside organized sessions was among the most rewarding aspects of the course. Some even claimed to have profitably probed the intricacies of nucleosome structure and transcriptional regulation while basking in the sun on the beachl Obviously, it is difficult to catch the flavor of such varied proceedings in a book. (I cannot confirm the incident on the beach, never having found time to set foot there. Such is the fate of the director of a meeting. ) The ASI was judged a success -- and enthusiastically so -­ by most participants. Not only did we deepen our understanding of our scientific field, we made new friends and learned about scientific and nonscientific aspects of life in other countries and about issues that transcend international boundaries in our complex world. We hope that this volume will be as successful as the course was.

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Content:
Front Matter....Pages i-viii
Nucleosome Structure....Pages 1-16
Resynthesis of Histone Peptide Bonds on a DNA Matrix....Pages 17-25
How Does H1 Function in Chromatin?....Pages 27-36
Structural Studies on the Second Order of Chromatin Organization....Pages 37-53
Mitotic Chromosome Structure: An Update, December 1984....Pages 55-75
DNase I Hypersensitive Sites: A Structural Feature of Chromatin Associated with Gene Expression....Pages 77-101
Promoter Elements of Eukaryotic Protein-Coding Genes....Pages 103-119
Regulatory Elements in Steroid Hormone Inducible Genes: Structure and Evolution of DNA Sequences Recognized by Steroid Hormone Receptors....Pages 121-141
Structure and Regulation of the Human Metallothionein Gene Family....Pages 143-152
Expression and Chromatin Structure of the Alpha-Fetoprotein and Albumin Genes During Normal Development and Neoplasia....Pages 153-170
Transcriptional and Post-Transcriptional Control of Histone Gene Expression....Pages 171-176
Gene Expression and Interferon....Pages 177-188
Z-DNA and its Binding Proteins....Pages 189-201
Biochemistry and Molecular Biology of DNA Replication in Yeast....Pages 203-220
The Structures and Functions of the Low Molecular Weight HMG Proteins....Pages 221-238
Post-Translational Modification of the Low Molecular Weight HMG Chromosomal Proteins....Pages 239-247
Structure and Function in the HMG-1 Family of Chromosomal Proteins....Pages 249-261
Stacking Interactions: The Key Mechanism for Binding of Proteins to Single-Stranded Regions of Native and Damaged Nucleic Acids?....Pages 263-286
Organization and Evolution of the Protamine Genes of Salmonid Fishes....Pages 287-314
Chromatin Proteins and Chromatin Structure in Spermatogenesis....Pages 315-332
Back Matter....Pages 353-360
Diversity of Sperm Basic Chromosomal Proteins in the Vertebrates: A Phylogenetic Point of View....Pages 333-352

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Content:
Front Matter....Pages i-viii
Nucleosome Structure....Pages 1-16
Resynthesis of Histone Peptide Bonds on a DNA Matrix....Pages 17-25
How Does H1 Function in Chromatin?....Pages 27-36
Structural Studies on the Second Order of Chromatin Organization....Pages 37-53
Mitotic Chromosome Structure: An Update, December 1984....Pages 55-75
DNase I Hypersensitive Sites: A Structural Feature of Chromatin Associated with Gene Expression....Pages 77-101
Promoter Elements of Eukaryotic Protein-Coding Genes....Pages 103-119
Regulatory Elements in Steroid Hormone Inducible Genes: Structure and Evolution of DNA Sequences Recognized by Steroid Hormone Receptors....Pages 121-141
Structure and Regulation of the Human Metallothionein Gene Family....Pages 143-152
Expression and Chromatin Structure of the Alpha-Fetoprotein and Albumin Genes During Normal Development and Neoplasia....Pages 153-170
Transcriptional and Post-Transcriptional Control of Histone Gene Expression....Pages 171-176
Gene Expression and Interferon....Pages 177-188
Z-DNA and its Binding Proteins....Pages 189-201
Biochemistry and Molecular Biology of DNA Replication in Yeast....Pages 203-220
The Structures and Functions of the Low Molecular Weight HMG Proteins....Pages 221-238
Post-Translational Modification of the Low Molecular Weight HMG Chromosomal Proteins....Pages 239-247
Structure and Function in the HMG-1 Family of Chromosomal Proteins....Pages 249-261
Stacking Interactions: The Key Mechanism for Binding of Proteins to Single-Stranded Regions of Native and Damaged Nucleic Acids?....Pages 263-286
Organization and Evolution of the Protamine Genes of Salmonid Fishes....Pages 287-314
Chromatin Proteins and Chromatin Structure in Spermatogenesis....Pages 315-332
Back Matter....Pages 353-360
Diversity of Sperm Basic Chromosomal Proteins in the Vertebrates: A Phylogenetic Point of View....Pages 333-352
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